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Chemical Structure| 1107618-97-2 Chemical Structure| 1107618-97-2

Structure of 1107618-97-2

Chemical Structure| 1107618-97-2

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Product Details of [ 1107618-97-2 ]

CAS No. :1107618-97-2
Formula : C20H17F2N3O3
M.W : 385.36
SMILES Code : O=[N+](C1=CC=CN=C1N2CCC(CC2)=CC#CC3=CC(F)=C(OC)C(F)=C3)[O-]

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Application In Synthesis of [ 1107618-97-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1107618-97-2 ]

[ 1107618-97-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1107620-19-8 ]
  • [ 104197-14-0 ]
  • [ 1107618-97-2 ]
YieldReaction ConditionsOperation in experiment
With triethylamine;copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); In tetrahydrofuran; at 80℃; for 2h; A mixture of Compound 1c (50 mg, 0.206 mmol), <strong>[104197-14-0]4-bromo-2,6-difluoroanisole</strong> (45.9 mL, 0.206 mmol), bis(triphenylphosphine)palladium(II)dichloride (7.23 mg, 0.012 mmol), CuI (3.92 mg, 0.206 mmol) in anhydrous and degassed triethylamine (3 mL) was heated at 80 C. under a nitrogen atmosphere for 2 h in a sealed vessel. The reaction mixture was cooled, filtered on Celite, poured into water and extracted with EtOAc. The combined organic layers were washed with brine, dried on Na2SO4 and evaporated to dryness in vacuo to afford a residue, which was purified by flash chromatography (EtOAc-Petroleum Ether 10:90) affording the title product (22 mg).MS: [M+H]+=386.52
 

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