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Chemical Structure| 110706-48-4 Chemical Structure| 110706-48-4

Structure of 110706-48-4

Chemical Structure| 110706-48-4

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Product Details of [ 110706-48-4 ]

CAS No. :110706-48-4
Formula : C8H9ClO2
M.W : 172.61
SMILES Code : ClC1C=CC=C(CO)C=1CO
MDL No. :N/A

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Application In Synthesis of [ 110706-48-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 110706-48-4 ]

[ 110706-48-4 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 117-21-5 ]
  • [ 52010-22-7 ]
  • [ 70097-45-9 ]
  • [ 110706-48-4 ]
  • 2
  • [ 117-21-5 ]
  • [ 110706-48-4 ]
YieldReaction ConditionsOperation in experiment
With sodium hydroxide; In tetrahydrofuran; diethyl ether; water; EXAMPLE X2 1,2-Bishydroxymethyl-3-chlorobenzene To a suspension of 5 g of lithium aluminium hydride in 50 ml of dry diethyl ether was added dropwise with stirring a solution of 10 g (54.8 mmole) of <strong>[117-21-5]3-chlorophthalic anhydride</strong> in 120 ml of dry tetrahydrofuran. After heating under reflux for 6 hours, the mixture was cooled and treated carefully with 5 ml of water, 5 ml of 10% sodium hydroxide solution and 10 ml of water. The solution was filtered, the filtrate was dried over magnesium sulphate, filtered and evaporated to yield the title compound as a colourless waxy solid. 1 H nmr δ(CDCl3) 7.5-7.0 (3H,m); 4.79 (2H,s); 4.60 (2H,s); 4.4-3.9 (2H, broad m, exchanges with D2 O).
  • 3
  • [ 89-20-3 ]
  • [ 110706-49-5 ]
  • [ 110706-48-4 ]
YieldReaction ConditionsOperation in experiment
EXAMPLE X5 1,2-Bishydroxymethyl-4-chlorobenzene The title compound was prepared from 25 g (124.6 mmole) of <strong>[89-20-3]4-chlorophthalic acid</strong> by an analogous procedure to that described in Example X2. 1 H-nmr delta (CDCl3): 7.4-7.1(3H,m); 4.57(2H,broad m, exchanges with D2 O); 4.50(4H,s).
 

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