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Chemical Structure| 10549-27-6 Chemical Structure| 10549-27-6

Structure of 10549-27-6

Chemical Structure| 10549-27-6

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Product Details of [ 10549-27-6 ]

CAS No. :10549-27-6
Formula : C16H13Br
M.W : 285.18
SMILES Code : BrC1=CC(CCC2=CC=CC(CC3)=C42)=C4C3=C1
MDL No. :N/A

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Application In Synthesis of [ 10549-27-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 10549-27-6 ]

[ 10549-27-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 781-17-9 ]
  • [ 10549-27-6 ]
YieldReaction ConditionsOperation in experiment
41% With bromine;iron(III) chloride; In water; at 20℃; for 16h; Into an autoclave, 195 g of pyrene (available from HIROSHIMA WAKO Co., Ltd.), 1 liter of decaline (available from HIROSHIMA WAKO Co., Ltd.) and 78 g of 5% palladium carbon (available from HIROSHIMA WAKO Co., Ltd.) were placed, and the reaction was allowed to proceed at 160C for 21 hours under a hydrogen pressure of 70 kg/cm2. After the reaction was completed, the catalyst was separated by filtration and washed with 3 liters of chloroform. Then, chloroform was removed under a reduced pressured, and the remaining decaline solution was cooled with ice. The formed crystals were separated by filtration, washed with ethanol and dried, thereby obtaining 130 g of crystals. The obtained crystals in an amount of 126 g was suspended in 6.3 liters of purified water, and 2 g of ferric chloride monohydrate (available from HIROSHIMA WAKO Co., Ltd.) was added to the suspension. Then, an aqueous solution obtained from 30 milliliter of bromine and 3 liters of purified water was added dropwise at the room temperature over 4 hours. The reaction was then allowed to proceed at the room temperature for 12 hours. The formed crystals were separated by filtration, washed with water and ethanol and dissolved into 3 liters of chloroform. The resultant solution was washed with an aqueous solution of sodium hydrogencarbonate and water and dried with anhydrous magnesium sulfate, and the solvent was then removed. To the obtained residue, 1.5 liters of hexane was added. The formed crystals were separated by filtration, and 71.5 g of the crystals were obtained. Since m/z=286 and 284 in the field desorption mass analysis (FD-MS) of the obtained compound, which corresponded to C10H12Br=285, the compound was identified to be 4,5,9,10-tetrahydro-2-bromopyrene (the yield: 41%).
 

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