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Chemical Structure| 104197-15-1 Chemical Structure| 104197-15-1

Structure of 104197-15-1

Chemical Structure| 104197-15-1

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Product Details of [ 104197-15-1 ]

CAS No. :104197-15-1
Formula : C8H5F2NO
M.W : 169.13
SMILES Code : N#CC1=CC(F)=C(OC)C(F)=C1
MDL No. :MFCD04115912
InChI Key :FTPRNOSXVHXNSB-UHFFFAOYSA-N
Pubchem ID :10583253

Safety of [ 104197-15-1 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302+H312-H315-H319-H331-H335
Precautionary Statements:P261-P280-P305+P351+P338-P311
Class:6.1
UN#:3439
Packing Group:

Application In Synthesis of [ 104197-15-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 104197-15-1 ]

[ 104197-15-1 ] Synthesis Path-Downstream   1~2

  • 2
  • [ 544-92-3 ]
  • [ 104197-14-0 ]
  • [ 104197-15-1 ]
YieldReaction ConditionsOperation in experiment
In N,N-dimethyl-formamide; at 120℃; for 48h; (iii) 3 ,5-Difluoro-4-methoxybenzonitrileA mixture of 4-bromo-2,6-difluororhohenyl methyl ether (11.5 g, 0.0516 mol; see step (ii) above) and CuCN (6.92 g, 0.0774 mol) in dry DMF (15 mL) was stirred at 120C for two days under nitrogen atmosphere. The reaction mixture was cooled to room temperature, diluted with water and extracted with ethyl acetate. The organic layer was washed with water and brine and dried over sodium sulfate. Solvent evaporation under reduced pressure followed by column chromatography over silica gel, using 2% ethyl acetate in petroleum ether as eluent, yielded 2.7 g of the sub-title compound as a pale yellow solid.
 

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