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Chemical Structure| 1017264-51-5 Chemical Structure| 1017264-51-5

Structure of 1017264-51-5

Chemical Structure| 1017264-51-5

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Product Details of [ 1017264-51-5 ]

CAS No. :1017264-51-5
Formula : C9H11NO2S
M.W : 197.25
SMILES Code : O=S(C1=CC=CC(C2CC2)=C1)(N)=O
MDL No. :MFCD32632615

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Application In Synthesis of [ 1017264-51-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1017264-51-5 ]

[ 1017264-51-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1798-85-2 ]
  • [ 1017264-51-5 ]
YieldReaction ConditionsOperation in experiment
To a solution of 0.985 g <strong>[1798-85-2]1-bromo-3-cyclopropyl-benzene</strong> in 5 ml tetrahydrofuran was drop wise added at -78 C. 2.81 ml of a 1.6M solution of n-butyllithium in hexane. The mixture was stirred at -78 C. for 1.5 h. To the resulting suspension was added drop wise an excess (ca 1.5 ml) of sulfur dioxide (condensed with a dry ice cooling trap) and the mixture was allowed to taw to room temperature. The resulting suspension was stirred at room temperature for 45 min. The solid was collected by filtration washed with heptane and dried under high vacuum to constant weight to yield 0.67 g of a light yellow solid. This material was dissolved in 5.0 ml water and 0.467 g sodium acetate and 0.604 g hydroxylamine-O-sulfonic acid was added. The reaction mixture was stirred for 30 min at ambient temperature whereby a precipitate formed. The solid was collected and washed with water and dried to constant weight to yield 0.44 g of the title compound as a light yellow solid melting at 71.5-72.9 C.
 

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