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Chemical Structure| 100501-57-3 Chemical Structure| 100501-57-3

Structure of 100501-57-3

Chemical Structure| 100501-57-3
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Product Details of [ 100501-57-3 ]

CAS No. :100501-57-3
Formula : C12H19N3O2
M.W : 237.30
SMILES Code : CN1N=C2C(CN(C(OC(C)(C)C)=O)CC2)=C1
MDL No. :MFCD11044746

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Application In Synthesis of [ 100501-57-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 100501-57-3 ]

[ 100501-57-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 230301-11-8 ]
  • [ 74-88-4 ]
  • [ 100501-57-3 ]
  • tert-butyl 1-methyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate [ No CAS ]
YieldReaction ConditionsOperation in experiment
To a stuffed solution of tert-butyl 6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)- carboxylate (4 g, 17.9 mmol) in THF (100 mL) was added NaH (859 mg, 35.8 mmol) at 0 C. The mixture was stuffed at 0 C for 2h, then Mel (5g , 35.8mmol) was added dropwise at 0 C. The mixture was stuffed at 0 C for 3h, and then the 50 mL of H20 was added dropwise to the mixture. The resulting mixture was extracted with DCM (1 OOmLx3) and the combined organic layer was concentrated under reduce pressure to give the crude mixture of products as yellow solid (4 g, crude), which was used in next step without further purification. LCMS (mlz): 238.3 [M+H] .
 

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