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Chemical Structure| 1004527-71-2 Chemical Structure| 1004527-71-2

Structure of 1004527-71-2

Chemical Structure| 1004527-71-2

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Product Details of [ 1004527-71-2 ]

CAS No. :1004527-71-2
Formula : C10H16N2S
M.W : 196.31
SMILES Code : CC1=C(C)SC(C2CCNCC2)=N1
MDL No. :MFCD09891549

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Application In Synthesis of [ 1004527-71-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1004527-71-2 ]

[ 1004527-71-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 214834-18-1 ]
  • [ 814-75-5 ]
  • [ 1004527-71-2 ]
YieldReaction ConditionsOperation in experiment
13% With ethanol; at 200℃; for 0.0166667h;Microwave irradiation; -Bromobutan-2-one (124 mg, 0.8 mmol) and tert-butyl 4- carbamothioylpiperidine-1-carboxylate (200 mg, 0.8 mmol) in ethanol (1 iuL) were heated to 2000C for 1 minute under microwave irradiation. The black residue was purified by chromatography (DCM/MeOH/NH4OH 85/15/0.1) to yield 4,5- dimethyl-2- (piperidin-4-yl) thiazole as a brown solid (32 rag, 13%) : 1H NMR (400 MHz, DMSCHd6) δ 1.76-1.88 (m, 2H), 2.08-2.14 (m, 2H), 2.21 (s, 3H), 2.30 (s, 3H), 2.97-3.05 (m, 2H), 3.18- 3.24 (m, IH) , 3.30-3.35 (m, 2H); m/z (APCI pos) 197.1 (100%) [M+H] .
 

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