Home PROTAC Molecule p38/PROTAC
The family of mitogen-activated protein kinases (MAPK) comprises p38 MAP kinases, c-Jun N-terminal kinases (JNKs), and extracellular signal-regulated kinases (ERKs). These kinases play pivotal roles in various diseases such as inflammatory, autoimmune, neurodegenerative, metabolic diseases, and cancer. Recent advancements in the realm of MAPK inhibitors include selective inhibition targeting specific isoforms or downstream targets of MAPKs, along with approaches involving the degradation of target proteins.
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