Home Chemistry Organic Building Blocks Chlorides 2,4-Dichloro-1-Nitrobenzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —Cl,—NO2).
Electrophilic Substitution Reactions: Chlorobenzene's electron-rich aromatic ring can undergo substitution reactions where a hydrogen atom is replaced by a chlorine atom. For instance, it can undergo nitration, sulfonation, and Friedel-Crafts alkylation/acylation reactions.
Sulfonation: Nitrobenzene can be sulfonated to introduce a sulfonic acid group (-SO3H) onto the benzene ring. Sulfonation is carried out using concentrated sulfuric acid, which leads to the substitution of one of the hydrogen atoms on the ring.
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