Home Chemistry Organic Building Blocks Chlorides 1-Chloro-4-(Trifluoromethoxy)Benzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —Cl,—OCF3).
Sandmeyer Reaction: Chlorobenzene can be converted to other aryl halides through the Sandmeyer reaction, involving replacement of the chlorine atom with other halogens.
Nucleophilic Aromatic Substitution (NAS): In some cases, under appropriate conditions, nucleophiles can attack the benzene ring, leading to nucleophilic aromatic substitution reactions. The trifluoromethoxy group can influence the reactivity of the ring.
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2-Bromo-1-chloro-4-(trifluoromethoxy)benzene
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4-Chloro-2-nitro-1-(trifluoromethoxy)benzene
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(2-Chloro-5-(trifluoromethoxy)phenyl)boronic acid
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1-Chloro-2-nitro-4-(trifluoromethoxy)benzene
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5-Chloro-2-(trifluoromethoxy)benzaldehyde
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