630-580-1088 sales@ambeed.com
Structure Search

List Search MOL Search Structure Search

0
Chemistry
Boronic acids/esters >>1,3,2-DioxaborinaneAliphatic BoronsAromatic BoronsBCATBoric AcidsMIDA BoronatesOther BoronatesOther BoronsOxaborolesCatalysis Chemistry >>Achiral Crown LigandsC-H ActivationCarbon-Donor LigandsChiral Carbon LigandsChiral Crown LigandsChiral Olefin LigandsCross-CouplingCross-Coupling Using Transition Metal CatalystsDACH or Trost LigandsChemical Biology >>Conjugation Chemistry
GlycoscienceLinkers and CrosslinkersNucleic Acid ChemistryPEGylationPeptide ChemistryPhotolabile Protecting GroupHeterocyclic Building Blocks >>AcridinesAliphatic HeterocyclesAromatic HeterocyclesAzetidinesBenzimidazolesBenzisoxazolesBenzodioxansBenzofuransBenzothiazolesInorganic reagents >>Inorganic ReagentOrganic Building Blocks >>Acid AnhydridesAcyl ChloridesAlcohols
AldehydesAliphatic Chain HydrocarbonsAliphatic Cyclic HydrocarbonsAlkenesAlkylsAlkynesOrganometallic Reagents >>Grignard ReagentsOrganoarsenicOrganobismuthOrganoboronOrganogermaniumOrganolithiumOrganomercuryOrganosiliconOrganotinSpecialty Synthesis >>Enzyme-Mediated SynthesisFluorous SynthesisIonic LiquidsSolid Supported SynthesisStains and Dyes >>
Acid DyesAzoic DyesBasic DyesDirect DyesDisperse DyesDye IntermediatesMordant DyesOil DyesOther Stains and DyesSynthetic Reagents >>Acids and BasesC-C Bond FormationC-X Bond Formation (Halogen)C-X Bond Formation (Non-Halogen)Chelation and Complexation CompoundsCondensation AgentsCouplingDehydrating ReagentsFluorination Reagent
Pharmaceutical Intermediates
Analgesics >>BenzhydrocodoneBicifadineCapsaicinCelecoxibDebio-0827DexamethasoneElagolix SodiumEsketamine HydrochlorideIbuprofen SodiumAnesthetics >>CiprofolEsketamine HydrochlorideFospropofol Fospropofol DisodiumLevobupivacaine RemimazolamRemimazolam BesilateRemimazolam BesylateRopivacaineAnti-Addiction Agents >>Kakonein
Lofexidine HydrochlorideVarenicline Anti-inflammatory Agents >>ApremilastAsunaprevirATB-346 RelatedBalsalazide BaricitinibBencycloquidium BromideBudesonideCefiderocol Sulfate TosylateCeftaroline Fosamil AcetateAntibacterials >>AFN-1252 RelatedAlatrofloxacin Bedaquiline FumarateBesifloxacin BrilacidinCaspofungin AcetateCefiderocol Sulfate TosylateCefilavancinCeftaroline Fosamil
Anticonvulsants >>BrivaracetamCannabidiolEscitalopram OxalateEslicarbazepine Acetate RelatedFosphenytoinGabapentin EnacarbilJNJ-10234094LacosamideLevetiracetam RelatedAntidementia Agents >>Azeliragon RelatedDavunetideDonepezil HydrochlorideDonepezil RelatedEnsaculinFlorbetaben Flortaucipir F 18Flutemetamol IdalopirdineAntidepressants >>4-Chlorokynurenine
AgomelatineAgomelatine RelatedAllopregnanolone RelatedAmibegronAmitifadineAripiprazole RelatedBasimglurantBefloxatoneAntiemetics >>AprepitantAprepitant RelatedDolasetron RelatedDolasetron Mesylate HydrateFosaprepitant DimeglumineFosaprepitant RelatedOlanzapinePalonosetron RelatedPalonosetron HydrochlorideAntifungals >>Anidulafungin RelatedCabotegravirMore >>
Inhibitors/Agonists
ADC >>ADC AntibodyADC LinkerADC Linker with PayloadADC ToxinAntibody-Drug Conjugates (ADCs)Drug-Linker Conjugates for ADCAngiogenesis >>ALKBcr-AblBTKEGFRFAKFGFRFLT3HER2HIFAnti-infection >>3CLproAntibacterialAntibioticAntifungal
AntiparasiticAntiprotozoalAntiviralArenavirusBVDVApoptosis >>Apoptosis InducerBcl-2Bcl-6BRKc-Mycc-RETC/EBPCARDCaspaseAutophagy >>Atg4ATG4BATTECsAUTACsAutophagyBeclin1
FKBPLC3LRRK2Biochemical Reagent >>Cell Cycle >>AntifolateAPCAurora KinaseBUBCasein KinaseCdc25CDKChkCRISPR/Cas9Cytoskeleton >>ActinArp2/3 ComplexCYTHCytoplasmic DyneinDynaminFAKMore >>
Material Science
Aggregation-Induced Emission >>Other AIE BlocksTetraphenylethylene SeriesCOFs Linkers >>Aldehyde COFs LinkersAlkynyl COFs LinkersAmine COFs LinkersBoric COFs LinkersCyano COFs LinkersMultifunctional COFs linkersOther COFs linkersTriptycene SeriesElectronic Materials >>Battery MaterialsDye-Sensitized Solar Cell (DSSC) MaterialsElectronic MaterialLiquid Crystal (LC) MaterialsMolecular ConductorsOrganic Light-Emitting Diode (OLED) MaterialsOrganic Solar Cell (OPV) MaterialsOrganic Transistor (OFET) MaterialsPerovskite Solar Cell (PSC) MaterialsMagnetic Materials >>Magnetic Ionic LiquidsMagnetic MaterialMagnetic Metal Complexes
Organic Radicals Material Chemical Compounds >>Ligands for Functional Metal ComplexesLiquid Crystal (LC) Building BlocksPhthalocyanine Building BlocksPolymer and Macromolecule Semiconductor Building BlocksSmall Molecule Semiconductor Building BlocksSolubility Enhancing Reagents Supramolecular Host Materials MOF Ligands >>Carboxylic Acid MOF LigandsCarboxylic Acid Nitrogen-Containing Mixed MOF LigandsNitrogen-Containing MOF LigandsOther MOF LigandsNanomaterials >>Carbon NanomaterialsCeramic MembranesDendrimersGold NanoparticlesIron Oxide NanoparticlesMaterials by ApplicationMesoporous MaterialsMetals and Metal AlloysNano Minerals: NanoclaysOLED Materials >>Dopant
HostHTMOLED IntermediatesOther OLED related materialsOptical Materials >>Coumarin DyesCyanine and Squarylium DyesDCM DyesDipyrromethene DyesFluorescence MaterialsFluorescent ProbesHeat and Pressure Sensitive DyesNear-Infrared (NIR) DyesOrganic Non-Linear Optical (NLO) MaterialsOrganic Pigments >>Organic PigmentOther Materials >>Material OtherPolymer Science >>MonomersPolymer AdditivesPolymerization ReagentsPolymersResins
Contact Us
Home Cart 0 Sign in  
X
Chemistry
Heterocyclic Building Blocks
Pyrazoles
Tetrahydropyran Derivatives
3-Bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole
Chemistry
Heterocyclic Building Blocks
Organic Building Blocks
Pyrazoles
Tetrahydropyrans Bromides
Tetrahydropyran Derivatives
1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole

[ CAS No. 1044270-96-3 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
3d Animation Molecule Structure of 1044270-96-3
Chemical Structure| 1044270-96-3
Chemical Structure| 1044270-96-3
Structure of 1044270-96-3 * Storage: {[proInfo.prStorage]}

Please Login or Create an Account to: See VIP prices and availability

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

For Research Only 120K+ Compounds Competitive Price 1-2 Day Shipping

Quality Control of [ 1044270-96-3 ]

COA NMR CNMR HPLC LC-MS

Related Doc. of [ 1044270-96-3 ]

SDS Specification
Alternatived Products of [ 1044270-96-3 ]
Product Citations

Product Details of [ 1044270-96-3 ]

CAS No. :1044270-96-3 MDL No. :MFCD16659986
Formula : C8H11BrN2O Boiling Point : -
Linear Structure Formula :- InChI Key :DFCAINPSKAFWCM-UHFFFAOYSA-N
M.W : 231.09 Pubchem ID :57576537
Synonyms :

Safety of [ 1044270-96-3 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H302-H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 1044270-96-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1044270-96-3 ]

[ 1044270-96-3 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 110-87-2 ]
  • [ 1187582-58-6 ]
  • [ 1044270-96-3 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1.1: toluene-4-sulfonic acid / toluene / 3 h / 87 - 95 °C 2.1: diisopropylamine; TurboGrignard / tetrahydrofuran / 19 - 27 °C 2.2: 0.5 h / 5 - 10 °C
Reference： [1]Current Patent Assignee: FMC CORP - WO2021/76838, 2021, A1
  • 2
  • [ 449758-17-2 ]
  • [ 1187582-58-6 ]
  • [ 1044270-96-3 ]
YieldReaction ConditionsOperation in experiment
Stage #1: 1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole With TurboGrignard; diisopropylamine In tetrahydrofuran at 19 - 27℃; Stage #2: With 1,2-dibromo-1,1,2,2-tetrachloroethane In tetrahydrofuran at 5 - 10℃; for 0.5h; 3; 4 Example 3. Halogenation. 5 mL of zPr2NH and 120 mL of 1.3 M zPrMgCl/LiCl in THF was added to a solution of 19.4 g of l-(tetrahydro-2H-pyran-2-yl)-lH-pyrazole in 225 mL THF over 1 hour at room temperature. The temperature was maintained at a temperature from 19 °C to 27 °C during addition. The resulting mixture was stirred overnight at room temperature. After cooling to 5 °C, a solution of 1,2-dibromotetrachloroethane (51 g in 100 mL THF) was added over 30 min, during which the temperature was maintained below 10 °C. After warming to room temperature, saturated NH4CI (aq) was added. The organic layer was separated and concentrated to afford a dark oil comprising 5-bromo-l-(tetrahydro-2H-pyran-2-yl)-lH-pyrazole and 3-bromo-l- (tetrahydro-2H-pyran-2-yl)-lH-pyrazole.
Reference： [1]Current Patent Assignee: FMC CORP - WO2021/76838, 2021, A1 Location in patent: Paragraph 0285-0288

Tags: 1044270-96-3 synthesis path| 1044270-96-3 SDS| 1044270-96-3 COA| 1044270-96-3 purity| 1044270-96-3 application| 1044270-96-3 NMR| 1044270-96-3 COA| 1044270-96-3 structure

Recommend Products
Same Skeleton Products
Related Products
Isomers
Categories
Chemistry
Heterocyclic Building Blocks
Pyrazoles
1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole
Chemistry
Heterocyclic Building Blocks
Tetrahydropyrans
Tetrahydropyran Derivatives
Chemistry
Organic Building Blocks
Bromides

Technical Information

• Acid-Catalyzed α -Halogenation of Ketones • Addition of a Hydrogen Halide to an Internal Alkyne • Alcohols from Haloalkanes by Acetate Substitution-Hydrolysis • Alcohols React with PX3 • Alkyl Halide Occurrence • Alkylation of an Alkynyl Anion • An Alkane are Prepared from an Haloalkane • Convert Haloalkanes into Alcohols by SN2 • Friedel-Crafts Alkylation of Benzene with Haloalkanes • General Reactivity • Grignard Reaction • Halogenation of Alkenes • Hiyama Cross-Coupling Reaction • Kinetics of Alkyl Halides • Kumada Cross-Coupling Reaction • Methylation of Ammonia • Methylation of Ammonia • Reactions of Alkyl Halides with Reducing Metals • Reactions of Amines • Reactions of Dihalides • Stille Coupling • Substitution and Elimination Reactions of Alkyl Halides • Suzuki Coupling • Williamson Ether Syntheses
Historical Records

Related Functional Groups of
[ 1044270-96-3 ]

Bromides

Chemical Structure| 1187582-58-6

[ 1187582-58-6 ]

5-Bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole

Similarity: 0.92

Chemical Structure| 82099-98-7

[ 82099-98-7 ]

4-Bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole

Similarity: 0.84

Chemical Structure| 1416712-59-8

[ 1416712-59-8 ]

3-Bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazolo[4,3-c]pyridine

Similarity: 0.84

Chemical Structure| 1638764-64-3

[ 1638764-64-3 ]

5-Bromo-4-methyl-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole

Similarity: 0.83

Chemical Structure| 1788054-90-9

[ 1788054-90-9 ]

3-Bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-5-amine

Similarity: 0.83

Related Parent Nucleus of
[ 1044270-96-3 ]

Pyrazoles

Chemical Structure| 1187582-58-6

[ 1187582-58-6 ]

5-Bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole

Similarity: 0.92

Chemical Structure| 449758-17-2

[ 449758-17-2 ]

1-(2-Tetrahydropyranyl)-1H-pyrazole

Similarity: 0.85

Chemical Structure| 82099-98-7

[ 82099-98-7 ]

4-Bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole

Similarity: 0.84

Chemical Structure| 1638764-64-3

[ 1638764-64-3 ]

5-Bromo-4-methyl-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole

Similarity: 0.83

Tetrahydropyrans

Chemical Structure| 1187582-58-6

[ 1187582-58-6 ]

5-Bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole

Similarity: 0.92

Chemical Structure| 82099-98-7

[ 82099-98-7 ]

4-Bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole

Similarity: 0.84

Chemical Structure| 1416712-59-8

[ 1416712-59-8 ]

3-Bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazolo[4,3-c]pyridine

Similarity: 0.84

Chemical Structure| 1638764-64-3

[ 1638764-64-3 ]

5-Bromo-4-methyl-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole

Similarity: 0.83

Chemical Structure| 1788054-90-9

[ 1788054-90-9 ]

3-Bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-5-amine

Similarity: 0.83

; ;