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Chemical Structure| 93427-13-5 Chemical Structure| 93427-13-5
Chemical Structure| 93427-13-5

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2-(3,5-Dichlorophenyl)ethanol

CAS No.: 93427-13-5

4.5 *For Research Use Only !

Cat. No.: A493378 Purity: 95+%

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Product Details of [ 93427-13-5 ]

CAS No. :93427-13-5
Formula : C8H8Cl2O
M.W : 191.05
SMILES Code : ClC1=CC(Cl)=CC(CCO)=C1
MDL No. :MFCD06201039
InChI Key :HTPYSVJHLUKSRE-UHFFFAOYSA-N
Pubchem ID :2758138

Safety of [ 93427-13-5 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P261-P280-P305+P351+P338-P304+P340

Application In Synthesis [ 93427-13-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 93427-13-5 ]

[ 93427-13-5 ] Synthesis Path-Downstream   1~11

  • 1
  • [ 93427-13-5 ]
  • [ 93427-16-8 ]
  • 3
  • [ 93427-13-5 ]
  • [ 70555-56-5 ]
  • 4
  • [ 93427-13-5 ]
  • [ 2155-42-2 ]
  • 5
  • [ 93427-13-5 ]
  • [ 70555-58-7 ]
  • 7
  • [ 93427-13-5 ]
  • [ 93427-14-6 ]
YieldReaction ConditionsOperation in experiment
94% With 1H-imidazole; bromine; triphenylphosphine; In dichloromethane; at 20.0℃; for 0.5h; Step 1. Preparation of bromide 2[129] Bromine (0.80 mL, 15.5 mmol) was added to a solution of triphenylphosphine (4.12 g, 15.7 mmol) and imidazole (1.07 g, 15.7 mmol) in CH2CI2 (52 mL) at O C and the mixture was allowed to warm to room temperature. A solution of <strong>[93427-13-5]2-(3,5-dichlorophenyl)ethanol</strong> (1, 2.5 g, 13.1 mmol) in CH2CI2 (13 mL) was added via cannula. After 30 min at room temperature, the mixture was filtered through celite, washing with excess CH2CI2. The filtrate was concentrated in vacuo. The crude residue was purified by chromatography on 120 g silica (hexanes → 20% EtOAc/hexanes, gradient) to afford 3.13 g (94%) of bromide 2.
  • 8
  • [ 93427-13-5 ]
  • [ 73874-95-0 ]
  • [ 1613514-01-4 ]
YieldReaction ConditionsOperation in experiment
Example 59 3,5-Dichlorophenethyl 4-(4-(1H-1,2,3-triazol-4-yl)butanamido)piperidine-1-carboxylate The title compound was prepared from commercially available tert-butyl piperidin-4-ylcarbamate and <strong>[93427-13-5]2-(3,5-dichlorophenyl)ethanol</strong> analogously to Example 51 steps 2-4; LC-MS: Rt 1.24 mins; MS m/z 454.3, 456.3 [M+H]+; Method 2minLowpHv03
  • 9
  • [ 93427-13-5 ]
  • C8H5Cl2FO3S [ No CAS ]
  • 11
  • [ 93427-13-5 ]
  • [ 76-05-1 ]
  • 2,2,2-trifluoroethanoic acid-3,5-dichlorophenylethyl ester [ No CAS ]
 

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