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Chemical Structure| 17746-05-3 Chemical Structure| 17746-05-3
Chemical Structure| 17746-05-3

*Storage: Sealed in dry,Store in freezer, under -20°C.

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Undecanoyl Chloride

CAS No.: 17746-05-3

4.5 *For Research Use Only !

Cat. No.: A729736 Purity: 98%

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Product Details of [ 17746-05-3 ]

CAS No. :17746-05-3
Formula : C11H21ClO
M.W : 204.74
SMILES Code : CCCCCCCCCCC(Cl)=O
MDL No. :MFCD00000739
InChI Key :JUKPJGZUFHCZQI-UHFFFAOYSA-N
Pubchem ID :87287

Safety of [ 17746-05-3 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H314
Precautionary Statements:P280-P305+P351+P338-P310
Class:8
UN#:3265
Packing Group:

Application In Synthesis [ 17746-05-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 17746-05-3 ]
  • Downstream synthetic route of [ 17746-05-3 ]

[ 17746-05-3 ] Synthesis Path-Upstream   1~1

  • 1
  • [ 17746-05-3 ]
  • [ 58-22-0 ]
  • [ 5949-44-0 ]
YieldReaction ConditionsOperation in experiment
96% With pyridine In N,N-dimethyl-formamide at 0 - 20℃; for 1 h; Inert atmosphere First, under nitrogen, 5g of testosterone and 25ml of N,N-dimethylformamide (DMF, solvent), as well as 5ml pyridine (pyridine, base) are well-mixed, and then, at 0-10 deg.C was added 4.6ml undecanoyl chloride, and react at room temperature for 1 hour. After completion of the reaction, 5ml of water was added and stirred for 1 hour and the precipitated product was filtered, and then rinsed under aqueous acetone and the product dried in vacuo at room temperature after to obtain 7.6g of testosterone undecyl acid, yield 96percent, HPLC: 98.26percent. And then the, re-crystallization step is undecyl Testosterone 120g 480ml of acetone was added and stirred until the whole solution, followed by addition of 180ml of water and stirred for 0.5 hours, filtered and washed with an aqueous solution of acetone and run through again after crystallization resulting undecyl acid testosterone S crystalline (Form S),
References: [1] Patent: CN105732754, 2016, A, . Location in patent: Paragraph 0024; 0025; 0026; 0027; 0028.
 

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