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Chemical Structure| 149003-01-0 Chemical Structure| 149003-01-0
Chemical Structure| 149003-01-0

*Storage: Inert atmosphere,2-8°C.

Dexrazoxane HCl

CAS No.: 149003-01-0

Synonyms: ICRF-187 hydrochloride;ADR-529 hydrochloride;ICRF-187 HCl

4.5 *For Research Use Only !

Cat. No.: A1677080 Purity: 98%

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Product Details of [ Dexrazoxane HCl ]

CAS No. :149003-01-0
Formula : C11H17ClN4O4
M.W : 304.73
SMILES Code : C[C@H](N(C1)CC(NC1=O)=O)CN(C2)CC(NC2=O)=O.[H]Cl
Synonyms :
ICRF-187 hydrochloride;ADR-529 hydrochloride;ICRF-187 HCl
MDL No. :MFCD00912156
InChI Key :BIFMNMPSIYHKDN-FJXQXJEOSA-N
Pubchem ID :6918223

Safety of [ Dexrazoxane HCl ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.28mL

0.66mL

0.33mL

16.41mL

3.28mL

1.64mL

32.82mL

6.56mL

3.28mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline
Solubility: ≥ 3 mg/mL (8.79 mM); Clear solution
Protocol 2
Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)
Solubility: ≥ 3 mg/mL (8.79 mM); Clear solution
The prepared working fluid is recommended to be prepared now and used up as soon as possible in a short period of time. The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Add each solvent one by one:  PBS
Solubility: 130 mg/mL (381.02 mM); Clear solution; Need ultrasonic
 

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