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Chemical Structure| 129298-91-5 Chemical Structure| 129298-91-5
Chemical Structure| 129298-91-5

*Storage: Inert atmosphere,Store in freezer, under -20°C.

TNP-470

CAS No.: 129298-91-5

TNP-470, a synthetic analogue of fumagillin and an antiangiogenic compound, is inhibitor of methionine aminopeptidase-2 (MetAP-2) and can inhibit angiogenesis.

Synonyms: AGM-1470;O-(Chloroacetyl-carbamoyl) Fumagillol;NSC 642492

4.5 *For Research Use Only !

Cat. No.: A438276 Purity: 98%

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Product Details of [ TNP-470 ]

CAS No. :129298-91-5
Formula : C19H28ClNO6
M.W : 401.88
SMILES Code : C[C@@]1([C@@]2([C@@]3(CO3)CC[C@H]([C@H]2OC)OC(NC(CCl)=O)=O)[H])[C@H](O1)C/C=C(C)\C
Synonyms :
AGM-1470;O-(Chloroacetyl-carbamoyl) Fumagillol;NSC 642492
MDL No. :MFCD00870281

Safety of [ TNP-470 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.49mL

0.50mL

0.25mL

12.44mL

2.49mL

1.24mL

24.88mL

4.98mL

2.49mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2
 

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