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Chemical Structure| 1226759-47-2 Chemical Structure| 1226759-47-2
Chemical Structure| 1226759-47-2

LCL521 2HCl

CAS No.: 1226759-47-2

LCL521 2HCl, an inhibitor of acid ceramidase, shows anticancer actions of lysosomally targeted.

Synonyms: LCL521 dihydrochloride

4.5 *For Research Use Only !

Cat. No.: A328422 Purity: 99%

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Product Details of [ LCL521 2HCl ]

CAS No. :1226759-47-2
Formula : C31H54Cl2N4O7
M.W : 665.69
SMILES Code : CCCCCCCCCCCCCC(N[C@H](COC(CN(C)C)=O)[C@H](OC(CN(C)C)=O)C1=CC=C([N+]([O-])=O)C=C1)=O.[H]Cl.[H]Cl
Synonyms :
LCL521 dihydrochloride
MDL No. :MFCD31692338

Safety of [ LCL521 2HCl ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

ALK Isoform Comparison

Name Lipase Purity
XEN445 +++

endothelial lipase, IC50: 0.237 μM

99%
JZL184 ++++

MAGL, IC50: 8 nM

98%
Tanshinone IIA 97%
Orlistat 98%
Atglistatin ++

ATGL, IC50: 0.7 μM

99%

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.50mL

0.30mL

0.15mL

7.51mL

1.50mL

0.75mL

15.02mL

3.00mL

1.50mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2
The prepared working fluid is recommended to be prepared now and used up as soon as possible in a short period of time. The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1

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