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Naftifine HCl is a broad-spectrum allylamine antifungal agent primarily used for treating fungal infections like athlete’s foot, jock itch, and ringworm.
Synonyms: Naftifine (hydrochloride);AW 105-843;Naftifine HCl
4.5
*For Research Use Only !
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Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
CAS No. : | 65473-14-5 |
Formula : | C21H22ClN |
M.W : | 323.86 |
SMILES Code : | CN(C/C=C/C1=CC=CC=C1)CC2=CC=CC3=CC=CC=C23.[H]Cl |
Synonyms : |
Naftifine (hydrochloride);AW 105-843;Naftifine HCl
|
MDL No. : | MFCD00059047 |
GHS Pictogram: | ![]() |
Signal Word: | Warning |
Hazard Statements: | H302-H315-H319-H335 |
Precautionary Statements: | P261-P305+P351+P338 |
Clinical Trial:
NCT Number | Conditions | Phases | Recruitment | Completion Date | Locations |
NCT00750139 | Tinea Pedis A... More >>thlete's Foot Less << | Phase 3 | Completed | - | United States, Alabama ... More >> Radiant Research Birmingham, Alabama, United States, 35209 United States, California Dr. Felix Sigal Los Angeles, California, United States, 90010-3209 University of California San Francisco, Dept of Dermatology San Francisco, California, United States, 94115 United States, Florida FXM Research Miami, Florida, United States, 33175 FXM Research Miramar, Florida, United States, 33027 United States, Illinois Glazer Dermatology Buffalo Grove, Illinois, United States, 60089 United States, Louisiana Tulane University Health Services New Orleans, Louisiana, United States, 70112 United States, Michigan Silverton Skin Institute Grand Blanc, Michigan, United States, 48439 United States, North Carolina Zoe Draelos, MD High Point, North Carolina, United States, 27262 United States, Ohio Haber Dermatology Euclid, Ohio, United States, 44118 United States, Oregon Oregon Dermatology and Research Center Portland, Oregon, United States, 97210 United States, Pennsylvania Paddington Testing Company Philadelphia, Pennsylvania, United States, 19103 Temple University School of Podiatric Medicine Philadelphia, Pennsylvania, United States, 19107 United States, South Carolina Coastal Carolina Research Center Mt. Pleasant, South Carolina, United States, 29464 United States, Texas J & S Studies College Station, Texas, United States, 77845 Research Across America Dallas, Texas, United States, 75234 Research Across America Plano, Texas, United States, 75093 Less << |
NCT00253305 | Onychomycosis | Phase 2 | Completed | - | United States, Alabama ... More >> University of Alabama at Birmingham Birmingham, Alabama, United States, 35233 United States, Arizona Genova Clinical Research, Inc. Tucson, Arizona, United States, 85741 United States, Florida Greater Miami Skin and Laser Center Miami Beach, Florida, United States, 33140 United States, Missouri Washington University St. Louis, Missouri, United States, 63110 United States, Oregon Northwest Cutaneous research Portland, Oregon, United States, 97210 Less << |
NCT02658292 | Tinea Capitis | Phase 2 | Withdrawn | - | - |
NCT01289015 | - | Completed | - | - | |
NCT01712360 | Tinea Pedis T... More >>inea Cruris Less << | Phase 4 | Completed | - | United States, Texas ... More >> Merz Investigative Site #001272 Austin, Texas, United States, 78759 Merz Investigative Site #001261 College Station, Texas, United States, 77802 Dominican Republic Merz Investigative Site #180001 Santo Domingo, Dominican Republic Honduras Merz Investigative Site #504001 San Pedro Sula, Honduras Less << |
NCT01290341 | Tinea Pedis | Phase 3 | Completed | - | - |
NCT01290341 | - | Completed | - | - | |
NCT01712360 | - | Completed | - | - | |
NCT02227290 | Tinea Corporis | Phase 4 | Completed | - | United States, Arizona ... More >> Merz Investigative Site#001316 Tucson, Arizona, United States, 85712 United States, California Investigative Site# 0010320 Encino, California, United States, 91436 Merz Investigative Site#001313 Fremont, California, United States, 94538 Merz Investigative Site#001301 San Diego, California, United States, 92102 United States, Florida Merz Investigative Site#001312 Miami, Florida, United States, 33144 Merz Investigative Site#001311 Miami, Florida, United States, 33175 Merz Investigative Site #001310 Miramar, Florida, United States, 33027 United States, Missouri Merz Investigative Site#001307 Saint Joseph, Missouri, United States, 64506 United States, Nebraska Merz Investigative Site#001309 Omaha, Nebraska, United States, 68114 United States, Nevada Merz Investigative Site#001314 Henderson, Nevada, United States, 89074 United States, North Carolina Merz Investigative Site#001126 Raleigh, North Carolina, United States, 27612 Merz Investigative Site#001293 Winston Salem, North Carolina, United States, 27104 United States, Oregon Investigative Site# 0010319 Gresham, Oregon, United States, 97030 United States, Tennessee Merz Investigative Site#001097 Nashville, Tennessee, United States, 37215 Dominican Republic Merz Investigative Site#180002 San Cristobal, Dominican Republic Merz Investigative Site# 180001 Santo Domingo, Dominican Republic Honduras Merz Investigative Site#504001 San Pedro Sula, Honduras Panama Merz Investigative Site#507001 Panama City, Panama Puerto Rico Merz Investigative Site#001279 Cidra, Puerto Rico, 00739 Less << |
NCT01580891 | Tinea Pedis | Phase 1 | Completed | - | - |
NCT01885156 | Tinea Cruris ... More >>Jock Itch Less << | Phase 3 | Completed | - | Belize ... More >> Merz Investigational Site # 501001 Belize City, Belize Merz Investigational Site # 501002 Belize City, Belize Dominican Republic Merz Investigative Site # 180002 San Cristobal, Dominican Republic Merz Investigative Site # 180001 Santo Domingo, Dominican Republic Honduras Merz Investigative Site # 504001 San Pedro Sula, Honduras Less << |
NCT02466867 | Tinea Corporis | Phase 4 | Completed | - | United States, Texas ... More >> Merz Investigative Site#001261 College Station, Texas, United States, 77845 Dominican Republic Merz Investigative Site#180001 Santo Domingo, Dominican Republic Honduras Merz Investigative Site #504001 San Pedro Sula, Honduras Less << |
NCT01289015 | Tinea Pedis | Phase 3 | Completed | - | - |
NCT02132260 | Tinea Pedis | Phase 1 | Completed | - | - |
NCT00750139 | - | Completed | - | - | |
NCT02633813 | Tinea Pedis | Phase 3 | Completed | - | United States, Florida ... More >> Moore Clinical Research Inc Brandon, Florida, United States, 33511 Savin Medical Group Research Miami, Florida, United States, 33014 International Dermatology Research, Inc, Miami, Florida, United States, 33144 FXM Research Corp Miami, Florida, United States, 33175 FXM Research Miramar Miramar, Florida, United States, 33027 South Tampa, MOORE Clinical Research, Inc. Tampa, Florida, United States, 33609 North Tampa MOORE Clinical Research, Inc. Tampa, Florida, United States, 33618 United States, Missouri Medi Search Saint Joseph, Missouri, United States, 64506 United States, Texas Bellaire Dermatology Associates Bellaire, Texas, United States, 77401 Research Across America Dallas, Texas, United States, 75234 Family Practise Mesquite, Texas, United States, 75149 Research Across America Plano, Texas, United States, 75093 Dominican Republic Instituto Dermatológico y Cirugía de Piel Santo Domingo, San Cristóbal, Dominican Republic, 91000 Instituto Dermatológico Barrio Maria Auxiliadora, Santo Domingo, Dominican Republic, 10305 Less << |
NCT02335255 | Tinea Pedis | Phase 1 | Completed | - | - |
Bio Calculators | ||||
Preparing Stock Solutions | ![]() | 1mg | 5mg | 10mg |
1 mM 5 mM 10 mM | 3.09mL 0.62mL 0.31mL | 15.44mL 3.09mL 1.54mL | 30.88mL 6.18mL 3.09mL |
Tags: 65473-14-5 synthesis path| 65473-14-5 SDS| 65473-14-5 COA| 65473-14-5 purity| 65473-14-5 application| 65473-14-5 NMR| 65473-14-5 COA| 65473-14-5 structure
Precautionary Statements-General | |
Code | Phrase |
P101 | If medical advice is needed,have product container or label at hand. |
P102 | Keep out of reach of children. |
P103 | Read label before use |
Prevention | |
Code | Phrase |
P201 | Obtain special instructions before use. |
P202 | Do not handle until all safety precautions have been read and understood. |
P210 | Keep away from heat/sparks/open flames/hot surfaces. - No smoking. |
P211 | Do not spray on an open flame or other ignition source. |
P220 | Keep/Store away from clothing/combustible materials. |
P221 | Take any precaution to avoid mixing with combustibles |
P222 | Do not allow contact with air. |
P223 | Keep away from any possible contact with water, because of violent reaction and possible flash fire. |
P230 | Keep wetted |
P231 | Handle under inert gas. |
P232 | Protect from moisture. |
P233 | Keep container tightly closed. |
P234 | Keep only in original container. |
P235 | Keep cool |
P240 | Ground/bond container and receiving equipment. |
P241 | Use explosion-proof electrical/ventilating/lighting/equipment. |
P242 | Use only non-sparking tools. |
P243 | Take precautionary measures against static discharge. |
P244 | Keep reduction valves free from grease and oil. |
P250 | Do not subject to grinding/shock/friction. |
P251 | Pressurized container: Do not pierce or burn, even after use. |
P260 | Do not breathe dust/fume/gas/mist/vapours/spray. |
P261 | Avoid breathing dust/fume/gas/mist/vapours/spray. |
P262 | Do not get in eyes, on skin, or on clothing. |
P263 | Avoid contact during pregnancy/while nursing. |
P264 | Wash hands thoroughly after handling. |
P265 | Wash skin thouroughly after handling. |
P270 | Do not eat, drink or smoke when using this product. |
P271 | Use only outdoors or in a well-ventilated area. |
P272 | Contaminated work clothing should not be allowed out of the workplace. |
P273 | Avoid release to the environment. |
P280 | Wear protective gloves/protective clothing/eye protection/face protection. |
P281 | Use personal protective equipment as required. |
P282 | Wear cold insulating gloves/face shield/eye protection. |
P283 | Wear fire/flame resistant/retardant clothing. |
P284 | Wear respiratory protection. |
P285 | In case of inadequate ventilation wear respiratory protection. |
P231 + P232 | Handle under inert gas. Protect from moisture. |
P235 + P410 | Keep cool. Protect from sunlight. |
Response | |
Code | Phrase |
P301 | IF SWALLOWED: |
P304 | IF INHALED: |
P305 | IF IN EYES: |
P306 | IF ON CLOTHING: |
P307 | IF exposed: |
P308 | IF exposed or concerned: |
P309 | IF exposed or if you feel unwell: |
P310 | Immediately call a POISON CENTER or doctor/physician. |
P311 | Call a POISON CENTER or doctor/physician. |
P312 | Call a POISON CENTER or doctor/physician if you feel unwell. |
P313 | Get medical advice/attention. |
P314 | Get medical advice/attention if you feel unwell. |
P315 | Get immediate medical advice/attention. |
P320 | |
P302 + P352 | IF ON SKIN: wash with plenty of soap and water. |
P321 | |
P322 | |
P330 | Rinse mouth. |
P331 | Do NOT induce vomiting. |
P332 | IF SKIN irritation occurs: |
P333 | If skin irritation or rash occurs: |
P334 | Immerse in cool water/wrap n wet bandages. |
P335 | Brush off loose particles from skin. |
P336 | Thaw frosted parts with lukewarm water. Do not rub affected area. |
P337 | If eye irritation persists: |
P338 | Remove contact lenses, if present and easy to do. Continue rinsing. |
P340 | Remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P341 | If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P342 | If experiencing respiratory symptoms: |
P350 | Gently wash with plenty of soap and water. |
P351 | Rinse cautiously with water for several minutes. |
P352 | Wash with plenty of soap and water. |
P353 | Rinse skin with water/shower. |
P360 | Rinse immediately contaminated clothing and skin with plenty of water before removing clothes. |
P361 | Remove/Take off immediately all contaminated clothing. |
P362 | Take off contaminated clothing and wash before reuse. |
P363 | Wash contaminated clothing before reuse. |
P370 | In case of fire: |
P371 | In case of major fire and large quantities: |
P372 | Explosion risk in case of fire. |
P373 | DO NOT fight fire when fire reaches explosives. |
P374 | Fight fire with normal precautions from a reasonable distance. |
P376 | Stop leak if safe to do so. Oxidising gases (section 2.4) 1 |
P377 | Leaking gas fire: Do not extinguish, unless leak can be stopped safely. |
P378 | |
P380 | Evacuate area. |
P381 | Eliminate all ignition sources if safe to do so. |
P390 | Absorb spillage to prevent material damage. |
P391 | Collect spillage. Hazardous to the aquatic environment |
P301 + P310 | IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
P301 + P312 | IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
P301 + P330 + P331 | IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. |
P302 + P334 | IF ON SKIN: Immerse in cool water/wrap in wet bandages. |
P302 + P350 | IF ON SKIN: Gently wash with plenty of soap and water. |
P303 + P361 + P353 | IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. |
P304 + P312 | IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell. |
P304 + P340 | IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. |
P304 + P341 | IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P305 + P351 + P338 | IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
P306 + P360 | IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes. |
P307 + P311 | IF exposed: call a POISON CENTER or doctor/physician. |
P308 + P313 | IF exposed or concerned: Get medical advice/attention. |
P309 + P311 | IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician. |
P332 + P313 | IF SKIN irritation occurs: Get medical advice/attention. |
P333 + P313 | IF SKIN irritation or rash occurs: Get medical advice/attention. |
P335 + P334 | Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages. |
P337 + P313 | IF eye irritation persists: Get medical advice/attention. |
P342 + P311 | IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. |
P370 + P376 | In case of fire: Stop leak if safe to Do so. |
P370 + P378 | In case of fire: |
P370 + P380 | In case of fire: Evacuate area. |
P370 + P380 + P375 | In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion. |
P371 + P380 + P375 | In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion. |
Storage | |
Code | Phrase |
P401 | |
P402 | Store in a dry place. |
P403 | Store in a well-ventilated place. |
P404 | Store in a closed container. |
P405 | Store locked up. |
P406 | Store in corrosive resistant/ container with a resistant inner liner. |
P407 | Maintain air gap between stacks/pallets. |
P410 | Protect from sunlight. |
P411 | |
P412 | Do not expose to temperatures exceeding 50 oC/ 122 oF. |
P413 | |
P420 | Store away from other materials. |
P422 | |
P402 + P404 | Store in a dry place. Store in a closed container. |
P403 + P233 | Store in a well-ventilated place. Keep container tightly closed. |
P403 + P235 | Store in a well-ventilated place. Keep cool. |
P410 + P403 | Protect from sunlight. Store in a well-ventilated place. |
P410 + P412 | Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF. |
P411 + P235 | Keep cool. |
Disposal | |
Code | Phrase |
P501 | Dispose of contents/container to ... |
P502 | Refer to manufacturer/supplier for information on recovery/recycling |
Physical hazards | |
Code | Phrase |
H200 | Unstable explosive |
H201 | Explosive; mass explosion hazard |
H202 | Explosive; severe projection hazard |
H203 | Explosive; fire, blast or projection hazard |
H204 | Fire or projection hazard |
H205 | May mass explode in fire |
H220 | Extremely flammable gas |
H221 | Flammable gas |
H222 | Extremely flammable aerosol |
H223 | Flammable aerosol |
H224 | Extremely flammable liquid and vapour |
H225 | Highly flammable liquid and vapour |
H226 | Flammable liquid and vapour |
H227 | Combustible liquid |
H228 | Flammable solid |
H229 | Pressurized container: may burst if heated |
H230 | May react explosively even in the absence of air |
H231 | May react explosively even in the absence of air at elevated pressure and/or temperature |
H240 | Heating may cause an explosion |
H241 | Heating may cause a fire or explosion |
H242 | Heating may cause a fire |
H250 | Catches fire spontaneously if exposed to air |
H251 | Self-heating; may catch fire |
H252 | Self-heating in large quantities; may catch fire |
H260 | In contact with water releases flammable gases which may ignite spontaneously |
H261 | In contact with water releases flammable gas |
H270 | May cause or intensify fire; oxidizer |
H271 | May cause fire or explosion; strong oxidizer |
H272 | May intensify fire; oxidizer |
H280 | Contains gas under pressure; may explode if heated |
H281 | Contains refrigerated gas; may cause cryogenic burns or injury |
H290 | May be corrosive to metals |
Health hazards | |
Code | Phrase |
H300 | Fatal if swallowed |
H301 | Toxic if swallowed |
H302 | Harmful if swallowed |
H303 | May be harmful if swallowed |
H304 | May be fatal if swallowed and enters airways |
H305 | May be harmful if swallowed and enters airways |
H310 | Fatal in contact with skin |
H311 | Toxic in contact with skin |
H312 | Harmful in contact with skin |
H313 | May be harmful in contact with skin |
H314 | Causes severe skin burns and eye damage |
H315 | Causes skin irritation |
H316 | Causes mild skin irritation |
H317 | May cause an allergic skin reaction |
H318 | Causes serious eye damage |
H319 | Causes serious eye irritation |
H320 | Causes eye irritation |
H330 | Fatal if inhaled |
H331 | Toxic if inhaled |
H332 | Harmful if inhaled |
H333 | May be harmful if inhaled |
H334 | May cause allergy or asthma symptoms or breathing difficulties if inhaled |
H335 | May cause respiratory irritation |
H336 | May cause drowsiness or dizziness |
H340 | May cause genetic defects |
H341 | Suspected of causing genetic defects |
H350 | May cause cancer |
H351 | Suspected of causing cancer |
H360 | May damage fertility or the unborn child |
H361 | Suspected of damaging fertility or the unborn child |
H361d | Suspected of damaging the unborn child |
H362 | May cause harm to breast-fed children |
H370 | Causes damage to organs |
H371 | May cause damage to organs |
H372 | Causes damage to organs through prolonged or repeated exposure |
H373 | May cause damage to organs through prolonged or repeated exposure |
Environmental hazards | |
Code | Phrase |
H400 | Very toxic to aquatic life |
H401 | Toxic to aquatic life |
H402 | Harmful to aquatic life |
H410 | Very toxic to aquatic life with long-lasting effects |
H411 | Toxic to aquatic life with long-lasting effects |
H412 | Harmful to aquatic life with long-lasting effects |
H413 | May cause long-lasting harmful effects to aquatic life |
H420 | Harms public health and the environment by destroying ozone in the upper atmosphere |
Sorry,this product has been discontinued.
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