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Dexrazoxane is both an antimitotic agent with immunosuppressive properties and a cardioprotective agent.
Synonyms: ICRF-187;ADR-529;Zinecard. Foreign brand names: Cardioxane Savene.
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Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
CAS No. : | 24584-09-6 |
Formula : | C11H16N4O4 |
M.W : | 268.27 |
SMILES Code : | C[C@@H](CN1CC(=O)NC(=O)C1)N1CC(=O)NC(=O)C1 |
Synonyms : |
ICRF-187;ADR-529;Zinecard. Foreign brand names: Cardioxane Savene.
|
MDL No. : | MFCD00866449 |
InChI Key : | BMKDZUISNHGIBY-ZETCQYMHSA-N |
Pubchem ID : | 71384 |
GHS Pictogram: | ![]() |
Signal Word: | Warning |
Hazard Statements: | H315-H319-H335 |
Precautionary Statements: | P261-P305+P351+P338 |
Target |
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Clinical Trial:
NCT Number | Conditions | Phases | Recruitment | Completion Date | Locations |
NCT02786719 | Neuroblastoma | Not Applicable | Recruiting | June 2019 | United States, California ... More >> Rady Children's Hospital Recruiting San Diego, California, United States, 92123 Contact: Laura Conner 858-966-5983 LConner@rchsd.org Principal Investigator: Peter Zage, MD United States, Texas Texas Children's Hospital Recruiting Houston, Texas, United States, 77030 Contact: Sarah Whittle, MD, BA 832-822-4242 sbwhittl@txch.org Less << |
NCT00077285 | Sarcoma | Phase 2 | Active, not recruiting | October 2019 | United States, New York ... More >> Memorial Sloan-Kettering Cancer Center New York, New York, United States, 10065 Less << |
NCT00400946 | Drug/Agent Toxicity by Tissue/... More >>Organ Leukemia Less << | Phase 3 | Active, not recruiting | June 2019 | United States, Massachusetts ... More >> Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute Boston, Massachusetts, United States, 02115 United States, New York Albert Einstein Cancer Center at Albert Einstein College of Medicine Bronx, New York, United States, 10461 Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center New York, New York, United States, 10032 James P. Wilmot Cancer Center at University of Rochester Medical Center Rochester, New York, United States, 14642 United States, Rhode Island Hasbro Children's Hospital Providence, Rhode Island, United States, 02903 United States, Virginia INOVA Fairfax Hospital Fairfax, Virginia, United States, 22031 Canada, Ontario McMaster Children's Hospital at Hamilton Health Sciences Hamilton, Ontario, Canada, L8N 3Z5 Canada, Quebec Hopital Sainte Justine Montreal, Quebec, Canada, H3T 1C5 Centre de Recherche du Centre Hospitalier de l'Universite Laval Sainte Foy, Quebec, Canada, GIV 4G2 Puerto Rico San Jorge Children's Hospital Santurce, Puerto Rico, 00912 Less << |
NCT03063983 | Osteosarcoma | Phase 2 | Recruiting | January 31, 2022 | Brazil ... More >> Grupo de Apoio ao Adolescente e a Criança com Câncer Recruiting Sao Paulo, Brazil, 04039001 Contact: Antonio S Petrilli +55 (11) 5080-8400 sergiopetrilli@graacc.org.br Contact: Andreza A Senerchia +55 (11) 5080-8400 andrezasenerchia@graacc.org.br Less << |
NCT00019864 | Cardiac Toxicity ... More >> Sarcoma Less << | Phase 2 | Terminated | - | United States, Maryland ... More >> Warren Grant Magnuson Clinical Center - NCI Clinical Trials Referral Office Bethesda, Maryland, United States, 20892-1182 United States, Oklahoma Oklahoma University Cancer Institute Oklahoma City, Oklahoma, United States, 73104 United States, Texas Cook Children's Medical Center - Fort Worth Fort Worth, Texas, United States, 76104 Texas Children's Cancer Center and Hematology Service at Texas Children's Hospital Houston, Texas, United States, 77030-2399 Less << |
NCT00334867 | Sarcoma | Phase 3 | Withdrawn(withdrawn) | - | - |
NCT00581360 | Adenoid Cystic Carcinoma | Phase 2 | Completed | - | United States, Ohio ... More >> UPMC Cancer Center - Teramana Cancer Center - Steubenville Steubenville, Ohio, United States, 43952 United States, Pennsylvania UPMC Cancer Center - Beaver Beaver, Pennsylvania, United States, 15009 UPMC Cancer Center - Clairton Clairton, Pennsylvania, United States, 15025 UPMC Cancer Center - Arnold Palmer Pavilion - Greensburg Greensburg, Pennsylvania, United States, 15601 UPMC Cancer Center - Oakbrook Commons - Greensburg Greensburg, Pennsylvania, United States, 15601 UPMC Cancer Center - Indiana Indiana, Pennsylvania, United States, 15701 UPMC Cancer Center - John P. Murtha Pavilion - Johnstown Johnstown, Pennsylvania, United States, 15901 UPMC Cancer Center - McKeesport McKeesport, Pennsylvania, United States, 15132 UPMC Cancer Center -Haymaker Rd. Monroeville, Pennsylvania, United States, 15146 UPMC Cancer Center -Mosside Blvd. Monroeville, Pennsylvania, United States, 15146 UPMC Cancer Center - Sewickley Medical Oncology/Hematology Group Moon Township, Pennsylvania, United States, 15108 UPMC Cancer Center -Mt. Pleasant Mt. Pleasant, Pennsylvania, United States, 15666 UPMC Cancer Center -New Castle New Castle, Pennsylvania, United States, 16105 UPMC Cancer Center -Delafield Rd. Pittsburgh, Pennsylvania, United States, 15215 UPMC Cancer Center - Mercy Pittsburgh, Pennsylvania, United States, 15219 University of Pittsburgh Cancer Institute-Hillman Cancer Center Pittsburgh, Pennsylvania, United States, 15232 UPMC Cancer Center - Passavant Pittsburgh, Pennsylvania, United States, 15237 UPMC Cancer Center -Drake Pittsburgh, Pennsylvania, United States, 15241 UPMC Cancer Center - Uniontown Uniontown, Pennsylvania, United States, 15401 UPMC Cancer Center - Washington Washington, Pennsylvania, United States, 15301 UPMC Cancer Center -Wexford Wexford, Pennsylvania, United States, 15090 Less << |
NCT03007147 | B Acute Lymphoblastic Leukemia... More >> BCR-ABL1 Fusion Protein Expression Minimal Residual Disease Philadelphia Chromosome Positive T Acute Lymphoblastic Leukemia Untreated Adult Acute Lymphoblastic Leukemia Untreated Childhood Acute Lymphoblastic Leukemia Less << | Phase 3 | Recruiting | June 30, 2026 | - |
NCT03126916 | Childhood Ganglioneuroblastoma... More >> Childhood Neuroblastoma INRG Stage L2 INRG Stage M INRG Stage MS NMYC Gene Amplification Recurrent Neuroblastoma Less << | Phase 3 | Recruiting | June 30, 2026 | - |
NCT00581360 | - | Completed | - | - | |
NCT01864109 | Newly Diagnosed Ewing Sarcoma | Phase 2 | Recruiting | May 2020 | United States, New Jersey ... More >> Memoral Sloan Kettering Cancer Center Recruiting Basking Ridge, New Jersey, United States, 07920 Contact: Paul Meyers, MD 212-639-5952 Memorial Sloan Kettering Monmouth Recruiting Middletown, New Jersey, United States, 07748 Contact: Paul Meyers, MD 212-639-5952 United States, New York Memorial Sloan Kettering Commack Recruiting Commack, New York, United States, 11725 Contact: Paul Meyers, MD 212-639-5952 Memorial Sloan Kettering Westchester Recruiting Harrison, New York, United States, 10604 Contact: Paul Meyers, MD 212-639-5952 Memorial Sloan Kettering Cancer Center Recruiting New York, New York, United States, 10065 Contact: Paul Meyers, MD 212-639-5952 Contact: Emily Slotkin, MD 212-639-8856 Principal Investigator: Paul Meyers, MD Memorial Sloan Kettering Rockville Centre Recruiting Rockville Centre, New York, United States, 11570 Contact: Paul Meyers, MD 212-639-5952 Less << |
NCT00004853 | Ewing's Sarcoma ... More >> Rhabdomyosarcoma MPNST Synovial Sarcoma High-risk Sarcoma Less << | Phase 1 | Completed | - | United States, Maryland ... More >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Less << |
NCT03166813 | Cardiotoxicity | Not Applicable | Recruiting | December 31, 2020 | Hong Kong ... More >> Queen Mary Hospital Recruiting Hong Kong, Hong Kong Contact: Yiu-fai Cheung, MD 852-22554091 xfcheung@hkucc.hku.hk Principal Investigator: Yiu-fai Cheung, MD Sub-Investigator: Daniel KL Cheuk, MBBS Sub-Investigator: Vivian WY Li, PhD Less << |
NCT00084838 | - | Completed | - | - | |
NCT00400946 | - | Active, not recruiting | - | - | |
NCT03164057 | Acute Myeloid Leukemia ... More >> Myelodysplastic Syndromes Less << | Phase 2 | Recruiting | June 2027 | United States, California ... More >> City of Hope Comprehensive Cancer Center Recruiting Duarte, California, United States, 91010 Contact: Weili Sun, MD,PhD 800-826-4673 weilisun@coh.org Principal Investigator: Weili Sun, MD,PhD Children's Hospital of Central California Recruiting Madera, California, United States, 93636 Contact: Faisal Razzaqi, MD 866-353-5437 frazzaqi@valleychildrens.org Principal Investigator: Faisal Razzaqi, MD Children's Hospital of Orange County Recruiting Orange, California, United States, 92968 Contact: Jamie Frediani, MD 714-509-4348 jfrediani@choc.org Principal Investigator: Jamie Frediani, MD Lucile Packard Children's Hospital Stanford University Recruiting Palo Alto, California, United States, 94304 Contact: Norman J. Lacayo, MD 650-497-8953 lacayon@stanford.edu Principal Investigator: Norman J. Lacayo, MD Rady Children's Hospital and Health Center Recruiting San Diego, California, United States, 92123 Contact: Deborah Schiff, MD 858-966-5983 dschiff@chsd.org Principal Investigator: Deborah Schiff, MD United States, Tennessee St. Jude Children's Research Hospital Recruiting Memphis, Tennessee, United States, 38105 Contact: Tanja A. Gruber, MD, PhD 866-278-5833 tanja.gruber@stjude.org Contact: Referral Office 866-278-5833 referralinfo@stjude.org Principal Investigator: Tanja A. Gruber, MD, PhD United States, Texas Cook Children's Medical Center Recruiting Fort Worth, Texas, United States, 76104 Contact: Kenneth M. Heym, MD 682-885-4007 kenneth.heym@cookchildrens.org Principal Investigator: Kenneth M. Heym, MD Less << |
NCT03020030 | Acute Lymphoblastic Leukemia, ... More >>Pediatric Less << | Phase 3 | Recruiting | December 2026 | United States, Massachusetts ... More >> Boston Children's Hospital Recruiting Boston, Massachusetts, United States, 02115 Contact: Lewis Silverman, MD 617-632-6191 lewis_silverman@dfci.harvard.edu Principal Investigator: Lewis Silverman, MD Dana-Farber Cancer Institute Recruiting Boston, Massachusetts, United States, 02215 Contact: Lewis Silverman, MD 617-632-6191 lewis_silverman@dfci.harvard.edu Principal Investigator: Lewis Silverman, MD United States, New York Montefiore Medical Center Recruiting Bronx, New York, United States, 104617 Contact: Lisa Gennarini, MD lfigueir@montefiore.org Roswell Park Cancer Institute Recruiting Buffalo, New York, United States, 14263 Contact: Kara Kelly, MD Kara.Kelly@RoswellPark.org Columbia University Medical Center, Morgan Stanley Children's Hospital of New York-Presbyterian Recruiting New York, New York, United States, 10032 Contact: Justine Kahn, MD jk2034@cumc.columbia.edu Principal Investigator: Justine Kahn, MD United States, Rhode Island Hasbro Children's Hospital / Rhode Island Hospital Recruiting Providence, Rhode Island, United States, 02903 Contact: Jennifer Welch, MD jwelch@lifespan.org Canada, Quebec Hospital Sainte Justine, University of Montreal Recruiting Montreal, Quebec, Canada Contact: Jean-Marie LeClerc, MD jean-marie.leclerc@umontreal.ca Principal Investigator: Jean-Marie LeClerc, MD Centre Hospitalier U. de Quebec Recruiting Quebec City, Quebec, Canada Contact: Bruno Michon, MD bruno.michon@mail.chuq.qc.ca Principal Investigator: Bruno Michon, MD Less << |
NCT00980460 | Alpha Fetoprotein Increased ... More >> PRETEXT Stage 1 Hepatoblastoma PRETEXT Stage 2 Hepatoblastoma PRETEXT Stage 3 Hepatoblastoma PRETEXT Stage 4 Hepatoblastoma Less << | Phase 3 | Active, not recruiting | December 31, 2018 | - |
NCT02953184 | Antineoplastic Combined Chemot... More >>herapy Protocols Less << | Phase 2 | Recruiting | November 2020 | China, Jilin ... More >> First Hospital of Jilin University Recruiting Changchun, Jilin, China, 130021 Contact: Aiping Shi, Doctor 0086-13364308696 13364308696@163.com Contact: Zhimin Fan, Doctor 0086-13756661286 fanzhimn@163.com Sub-Investigator: Di Wu, Doctor Sub-Investigator: Hongyao Jia, Master Sub-Investigator: Xin Guan, Master Principal Investigator: Zhimin Fan, Doctor Principal Investigator: Haibo Wang, Doctor Sub-Investigator: Gang Nie, Doctor Less << |
NCT00084838 | Central Nervous System Tumor, ... More >>Pediatric Less << | Phase 2 | Completed | - | United States, California ... More >> Stanford Cancer Center Stanford, California, United States, 94305-5826 United States, Connecticut Yale Cancer Center New Haven, Connecticut, United States, 06520-8028 United States, Georgia AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Scottish Rite Campus Atlanta, Georgia, United States, 30342 United States, Illinois Children's Memorial Hospital - Chicago Chicago, Illinois, United States, 60614 United States, Maryland Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore, Maryland, United States, 21231-2410 United States, Massachusetts Children's Hospital Boston Boston, Massachusetts, United States, 02115 Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute Boston, Massachusetts, United States, 02115 United States, Minnesota Children's Hospitals and Clinics of Minnesota - Minneapolis Minneapolis, Minnesota, United States, 55404 United States, Nevada Sunrise Hospital and Medical Center Las Vegas, Nevada, United States, 89109 United States, Ohio Cleveland Clinic Taussig Cancer Center Cleveland, Ohio, United States, 44195 United States, Pennsylvania Children's Hospital of Philadelphia Philadelphia, Pennsylvania, United States, 19104 United States, Texas Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas Dallas, Texas, United States, 75390 Less << |
NCT00165087 | Acute Lymphoblastic Leukemia | Phase 3 | Terminated(Terminated by IRB f... More >>or continuing review) Less << | - | United States, Louisiana ... More >> Ochsner Clinic New Orleans, Louisiana, United States, 70121 United States, Maine Maine Medical Center Lewiston, Maine, United States, 04240 United States, Massachusetts Children's Hospital Boston Boston, Massachusetts, United States, 02115 Dana-Farber Cancer Institute Boston, Massachusetts, United States, 02115 United States, New York Mt. Sinai Medical Center New York, New York, United States, 10029 University of Rochester Rochester, New York, United States, 14627 Canada, Ontario McMaster University Hamilton, Ontario, Canada Canada, Quebec Laval University Montreal, Quebec, Canada Sainte Justine Hosptial Montreal, Quebec, Canada Puerto Rico San Jorge Children's Hospital Santurce, Puerto Rico, 00912 Less << |
NCT01871766 | Rhabdomyosarcoma | Phase 2 | Recruiting | June 2024 | United States, Florida ... More >> University of Florida Proton Therapy Institute Active, not recruiting Jacksonville, Florida, United States, 32206 Nemours Children's Clinic Active, not recruiting Jacksonville, Florida, United States, 32207 United States, Tennessee St. Jude Children's Research Hospital Recruiting Memphis, Tennessee, United States, 38105 Contact: Matthew J. Krasin, MD 866-278-5833 referralInfo@stjude.org Principal Investigator: Matthew J. Krasin, MD United States, Texas Cook Children's Medical Center Recruiting Fort Worth, Texas, United States, 76104 Contact: Karen Albritton, MD 682-885-2103 karen.albritton@cookchildrens.org Principal Investigator: Karen Albritton, MD Less << |
NCT00742924 | Sarcoma | Phase 1 | Completed | - | - |
NCT00410488 | Sarcoma Nause... More >>a Vomiting Less << | Not Applicable | Completed | - | United States, Texas ... More >> UT MD Anderson Cancer Center Houston, Texas, United States, 77030 Less << |
NCT00410488 | - | Completed | - | - | |
NCT00673179 | Osteosarcoma | Not Applicable | Terminated(Low accrual.) | - | United States, Texas ... More >> UT MD Anderson Cancer Center Houston, Texas, United States, 77030 Less << |
NCT00673179 | - | Terminated(Low accrual.) | - | - | |
NCT00098839 | Recurrent Childhood Acute Lymp... More >>hoblastic Leukemia Less << | Phase 1 Phase 2 | Completed | - | - |
NCT00001335 | Ewing's Sarcoma ... More >> Neuroblastoma Rhabdomyosarcoma Less << | Phase 2 | Completed | - | United States, Maryland ... More >> National Cancer Institute (NCI) Bethesda, Maryland, United States, 20892 Less << |
NCT00165178 | Acute Lymphoblastic Leukemia | Phase 3 | Completed | - | United States, Massachusetts ... More >> Dana-Farber Cancer Institute Boston, Massachusetts, United States, 02115 Less << |
NCT00098839 | - | Completed | - | - | |
NCT01258634 | Osteosarcoma ... More >>Lung Metastases Less << | Phase 1 | Terminated(PI no longer affili... More >>ated with institution; only 2 subjects enrolled) Less << | - | United States, Illinois ... More >> University of Chicago Department of Pediatrics Hematology/Oncology Chicago, Illinois, United States, 60637 Less << |
NCT01606878 | Recurrent Childhood Anaplastic... More >> Large Cell Lymphoma Recurrent Neuroblastoma Unspecified Childhood Solid Tumor, Protocol Specific Less << | Phase 1 | Active, not recruiting | - | - |
NCT03698227 | Advanced Soft Tissue Sarcoma | Phase 2 | Not yet recruiting | December 31, 2019 | Germany ... More >> Helios Klinikum Bad Saarow Not yet recruiting Bad Saarow, Germany, 15526 Contact: Daniel Pink, MD Less << |
NCT00003667 | Sarcoma | Phase 2 | Completed | - | United States, New York ... More >> Memorial Sloan-Kettering Cancer Center New York, New York, United States, 10021 United States, Texas University of Texas - MD Anderson Cancer Center Houston, Texas, United States, 77030 Less << |
NCT01523977 | Acute Lymphoblastic Leukemia | Phase 1 | Active, not recruiting | November 2018 | United States, California ... More >> UCSF San Francisco, California, United States, 94143 United States, Colorado Children's Hospital Colorado Aurora, Colorado, United States, 80045 United States, Georgia Children's Healthcare of Atlanta Atlanta, Georgia, United States, 30322 United States, Illinois Ann & Robert H. Lurie Children's Hospital of Chicago Chicago, Illinois, United States, 60611 United States, Massachusetts Boston Children's Hospital Boston, Massachusetts, United States, 02115 Dana-Farber Cancer Institute Boston, Massachusetts, United States, 02215 United States, New York Columbia University Medical Center New York, New York, United States, 12549 United States, Washington Seattle Children's Hospital Seattle, Washington, United States, 98105 Less << |
NCT01230983 | Cardiac Toxicity ... More >> Leukemia Lymphoma Less << | Phase 3 | Completed | - | - |
NCT00544778 | Sarcoma | Phase 2 | Terminated(The study was termi... More >>nated prematurely due to withdrawal of support by the sponsor.) Less << | - | - |
NCT01696669 | Ewing's Sarcoma | Phase 2 | Completed | - | Spain ... More >> Hospital Clínic de Barcelona Barcelona, Spain Hospital de la Santa Creu i Sant Pau Barcelona, Spain Hospital Vall d'Hebron Barcelona, Spain Hospital Sant Joan de Déu Esplugues de Llobregat, Spain Institut Català d'Oncologia l'Hospitalet Hospitalet de Llobregat, Spain Hospital Universitario de Canarias La Laguna, Spain Hospital Ramón y Cajal Madrid, Spain, 28034 Hospital Son Espases Palma de Mallorca, Spain Hospital Universitario Miguel Servet Zaragoza, Spain Less << |
NCT00039481 | Cardiac Toxicity ... More >> Unspecified Childhood Solid Tumor, Protocol Specific Less << | Phase 1 | Completed | - | United States, California ... More >> Children's Oncology Group Arcadia, California, United States, 91006-3776 Less << |
NCT00005578 | Cardiac Toxicity ... More >> Lymphoma Less << | Phase 3 | Completed | - | - |
NCT00011414 | Wilms' Tumor ... More >>Sarcoma Adenaocortical Carcinoma Refractory Cancer Coldrhood Cancer Less << | Phase 1 | Completed | - | United States, Maryland ... More >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Less << |
NCT00002827 | Cardiac Toxicity ... More >> Lymphoma Less << | Phase 3 | Completed | - | - |
NCT00003937 | Cardiac Toxicity ... More >> Sarcoma Less << | Phase 3 | Completed | - | - |
NCT00016276 | Cardiac Toxicity ... More >> Inflammatory Breast Cancer Stage IIIA Breast Cancer Stage IIIB Breast Cancer Stage IV Breast Cancer Less << | Phase 3 | Terminated(Administratively co... More >>mplete.) Less << | - | United States, Illinois ... More >> Cancer and Leukemia Group B Chicago, Illinois, United States, 60606 Less << |
NCT01790152 | - | Recruiting | - | - | |
NCT00038142 | Ewing's Sarcoma | Phase 2 | Terminated(Low Accrual) | - | United States, Texas ... More >> University of Texas MD Anderson Cancer Center Houston, Texas, United States, 77030 Less << |
NCT00548561 | Anthracycline Extravasation | Phase 2 Phase 3 | Completed | - | Denmark ... More >> Aalborg Hospital South Aalborg, Denmark, 9100 Rigshospitalet Copenhagen, Denmark, 2100 Herlev County Hospital Herlev, Denmark, 2730 Herlev Hospital Hematological Department Herlev, Denmark, 2730 Herning District Hospital Herning, Denmark, 7400 Hilleroed Hospital Hilleroed, Denmark, 3400 Odense University Hospital Odense, Denmark, 5000 C Roskilde County Hospital Roskilde, Denmark, 4000 Viborg Hospital Viborg, Denmark, 8800 Less << |
NCT00550901 | Unspecified Adult Solid Tumor,... More >> Protocol Specific Less << | Phase 1 | Completed | - | - |
NCT00933985 | Acute Leukemias of Ambiguous L... More >>ineage Acute Undifferentiated Leukemia Angioimmunoblastic T-cell Lymphoma Blastic Phase Chronic Myelogenous Leukemia Childhood Burkitt Lymphoma Childhood Chronic Myelogenous Leukemia Childhood Diffuse Large Cell Lymphoma Childhood Immunoblastic Large Cell Lymphoma Childhood Nasal Type Extranodal NK/T-cell Lymphoma Cutaneous B-cell Non-Hodgkin Lymphoma Hepatosplenic T-cell Lymphoma Intraocular Lymphoma Noncutaneous Extranodal Lymphoma Peripheral T-cell Lymphoma Recurrent Childhood Acute Lymphoblastic Leukemia Recurrent Childhood Acute Myeloid Leukemia Recurrent Childhood Anaplastic Large Cell Lymphoma Recurrent Childhood Grade III Lymphomatoid Granulomatosis Recurrent Childhood Large Cell Lymphoma Recurrent Childhood Lymphoblastic Lymphoma Recurrent Childhood Small Noncleaved Cell Lymphoma Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma Recurrent Mycosis Fungoides/Sezary Syndrome Recurrent/Refractory Childhood Hodgkin Lymphoma Refractory Chronic Lymphocytic Leukemia Refractory Hairy Cell Leukemia Relapsing Chronic Myelogenous Leukemia Small Intestine Lymphoma Unspecified Childhood Solid Tumor, Protocol Specific Less << | Phase 1 | Terminated | - | - |
NCT03589729 | Acute Myeloid Leukemia ... More >> Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive Blasts 10 Percent or More of Bone Marrow Nucleated Cells High Risk Myelodysplastic Syndrome Myeloid Sarcoma Myeloproliferative Neoplasm Philadelphia Chromosome Positive Less << | Phase 2 | Recruiting | December 31, 2020 | United States, Texas ... More >> M D Anderson Cancer Center Recruiting Houston, Texas, United States, 77030 Contact: Maro Ohanian 713-792-2631 Principal Investigator: Maro Ohanian Less << |
NCT00544778 | - | Terminated(The study was termi... More >>nated prematurely due to withdrawal of support by the sponsor.) Less << | - | - | |
NCT01596088 | Extravasations of Anthracyclin... More >>e Anti-cancer Agents Less << | Phase 1 Phase 2 | Completed | - | Japan ... More >> Japan Tokyo and Other Japanese City, Japan Less << |
NCT01596088 | - | Completed | - | - | |
NCT00955890 | Breast Cancer | Phase 2 | Terminated(Enrolled too slow) | - | China, Shanghai ... More >> Fudan University Cancer Hospital Shanghai, Shanghai, China, 200032 Less << |
NCT01627938 | Multiple Sclerosis | Phase 2 | Unknown | April 2016 | Germany ... More >> Department of Neurology, St. Josef-Hospital, Ruhr-University Bochum Bochum, Germany, 44791 Less << |
NCT00548704 | Extravasation | Phase 2 Phase 3 | Completed | - | Denmark ... More >> Aalborg Hospital South Aalborg, Denmark, 9100 Aarhus County Hospital Aarhus, Denmark, 8000 C Aarhus Municipality Hospital Aarhus, Denmark, 8000 C Rigshospitalet, Haematology Department Copenhagen, Denmark, 2100 Rigshospitalet, Oncology Department Copenhagen, Denmark, 2100 Esbjerg District Hospital Esbjerg, Denmark, 6700 Herlev County Hospital, Haematology Department Herlev, Denmark, 2730 Herlev County Hospital, Oncology Department Herlev, Denmark, 2730 Hilleroed Hospital Hilleroed, Denmark, 3400 Naestved District Hospital Naestved, Denmark, 4700 Odense University Hospital Odense, Denmark, 5000 C Roskilde County Hospital Roskilde, Denmark, 4000 Soenderborg Hospital Soenderborg, Denmark, 6400 Vejle Hospital Vejle, Denmark, 7100 Viborg Hospital Viborg, Denmark, 8800 Germany Evangelisches Bethesda Krankenhaus Essen Borbak Statt, Germany, 45355 Klinik für Gynäkologie und Geburtshilfe Frankfurt am Main, Germany, 60590 Klinik und Poliklinik für Innere Medizin Hamburg, Germany, 20246 Medizinische Hochschule Hannover Hannover, Germany, 30659 Universitäts Frauenklinik Kiel, Germany, 24105 Universitäts Medizinische Klinik Kiel, Germany, 24105 Frauenklinik com Roten Kreuz Munich, Germany, 80637 Universitäts Frauenklinik Rostock, Germany, 18057 Klinik für Gynäkologie und Gynäkologische Onkologie Wiesbaden, Germany, 65199 Italy Ospedale G.B. Morgagni L. Pierantoni Forli, Italy, 47100 Presidio Ospedaliero di Ravenna Ravenna, Italy, 48100 Ospedale degli Infermi Rimini, Italy, 47037 Ospedali Riuniti Trieste, Italy, 34100 Netherlands Netherland Cancer Institute Amsterdam, Netherlands, 1066 CX University Hospital Groningen, Netherlands, 9700 RB Willem Alexander Hospital Hertogenbosch, Netherlands, 5223 GV Poland Centre of Oncology - Krakow Division Krakow, Poland, 31-115 Maria Sklodowska-Curie Memorial Cancer Center Warsaw, Poland, 02-781 Dolnoslaski Centrum Onkologii oddzial Chemoterapii Wroclaw, Poland, 53-413 Less << |
NCT02519335 | Heart Defects, Congenital | Phase 1 | Terminated(PI no longer at thi... More >>s facility) Less << | - | United States, Texas ... More >> Medical City Children's Hospital Dallas, Texas, United States, 75230 Less << |
NCT00742924 | - | Completed | - | - | |
NCT02584309 | Sarcoma, Soft Tissue ... More >> Soft Tissue Sarcoma Undifferentiated Pleomorphic Sarcoma Leiomyosarcoma Liposarcoma Synovial Sarcoma Myxofibrosarcoma Angiosarcoma Fibrosarcoma Malignant Peripheral Nerve Sheath Tumor Epithelioid Sarcoma Less << | Phase 2 | Recruiting | October 31, 2023 | United States, Missouri ... More >> Washington University School of Medicine Recruiting Saint Louis, Missouri, United States, 63110 Contact: Brian A Van Tine, M.D., Ph.D. 314-747-8475 bvantine@wustl.edu Principal Investigator: Brian A Van Tine, M.D., Ph.D. Sub-Investigator: Ashley E Frith, M.D. Sub-Investigator: Douglas R Adkins, M.D. Sub-Investigator: Ronald J Krone, M.D. Sub-Investigator: Justin Vader, M.D. Sub-Investigator: George Heberton, M.D. Sub-Investigator: Peter Oppelt, M.D. Sub-Investigator: Caron Rigden, M.D. Sub-Investigator: Angela Hirbe, M.D. Less << |
Bio Calculators | ||||
Preparing Stock Solutions | ![]() | 1mg | 5mg | 10mg |
1 mM 5 mM 10 mM | 3.73mL 0.75mL 0.37mL | 18.64mL 3.73mL 1.86mL | 37.28mL 7.46mL 3.73mL |
Tags: 24584-09-6 synthesis path| 24584-09-6 SDS| 24584-09-6 COA| 24584-09-6 purity| 24584-09-6 application| 24584-09-6 NMR| 24584-09-6 COA| 24584-09-6 structure
Precautionary Statements-General | |
Code | Phrase |
P101 | If medical advice is needed,have product container or label at hand. |
P102 | Keep out of reach of children. |
P103 | Read label before use |
Prevention | |
Code | Phrase |
P201 | Obtain special instructions before use. |
P202 | Do not handle until all safety precautions have been read and understood. |
P210 | Keep away from heat/sparks/open flames/hot surfaces. - No smoking. |
P211 | Do not spray on an open flame or other ignition source. |
P220 | Keep/Store away from clothing/combustible materials. |
P221 | Take any precaution to avoid mixing with combustibles |
P222 | Do not allow contact with air. |
P223 | Keep away from any possible contact with water, because of violent reaction and possible flash fire. |
P230 | Keep wetted |
P231 | Handle under inert gas. |
P232 | Protect from moisture. |
P233 | Keep container tightly closed. |
P234 | Keep only in original container. |
P235 | Keep cool |
P240 | Ground/bond container and receiving equipment. |
P241 | Use explosion-proof electrical/ventilating/lighting/equipment. |
P242 | Use only non-sparking tools. |
P243 | Take precautionary measures against static discharge. |
P244 | Keep reduction valves free from grease and oil. |
P250 | Do not subject to grinding/shock/friction. |
P251 | Pressurized container: Do not pierce or burn, even after use. |
P260 | Do not breathe dust/fume/gas/mist/vapours/spray. |
P261 | Avoid breathing dust/fume/gas/mist/vapours/spray. |
P262 | Do not get in eyes, on skin, or on clothing. |
P263 | Avoid contact during pregnancy/while nursing. |
P264 | Wash hands thoroughly after handling. |
P265 | Wash skin thouroughly after handling. |
P270 | Do not eat, drink or smoke when using this product. |
P271 | Use only outdoors or in a well-ventilated area. |
P272 | Contaminated work clothing should not be allowed out of the workplace. |
P273 | Avoid release to the environment. |
P280 | Wear protective gloves/protective clothing/eye protection/face protection. |
P281 | Use personal protective equipment as required. |
P282 | Wear cold insulating gloves/face shield/eye protection. |
P283 | Wear fire/flame resistant/retardant clothing. |
P284 | Wear respiratory protection. |
P285 | In case of inadequate ventilation wear respiratory protection. |
P231 + P232 | Handle under inert gas. Protect from moisture. |
P235 + P410 | Keep cool. Protect from sunlight. |
Response | |
Code | Phrase |
P301 | IF SWALLOWED: |
P304 | IF INHALED: |
P305 | IF IN EYES: |
P306 | IF ON CLOTHING: |
P307 | IF exposed: |
P308 | IF exposed or concerned: |
P309 | IF exposed or if you feel unwell: |
P310 | Immediately call a POISON CENTER or doctor/physician. |
P311 | Call a POISON CENTER or doctor/physician. |
P312 | Call a POISON CENTER or doctor/physician if you feel unwell. |
P313 | Get medical advice/attention. |
P314 | Get medical advice/attention if you feel unwell. |
P315 | Get immediate medical advice/attention. |
P320 | |
P302 + P352 | IF ON SKIN: wash with plenty of soap and water. |
P321 | |
P322 | |
P330 | Rinse mouth. |
P331 | Do NOT induce vomiting. |
P332 | IF SKIN irritation occurs: |
P333 | If skin irritation or rash occurs: |
P334 | Immerse in cool water/wrap n wet bandages. |
P335 | Brush off loose particles from skin. |
P336 | Thaw frosted parts with lukewarm water. Do not rub affected area. |
P337 | If eye irritation persists: |
P338 | Remove contact lenses, if present and easy to do. Continue rinsing. |
P340 | Remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P341 | If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P342 | If experiencing respiratory symptoms: |
P350 | Gently wash with plenty of soap and water. |
P351 | Rinse cautiously with water for several minutes. |
P352 | Wash with plenty of soap and water. |
P353 | Rinse skin with water/shower. |
P360 | Rinse immediately contaminated clothing and skin with plenty of water before removing clothes. |
P361 | Remove/Take off immediately all contaminated clothing. |
P362 | Take off contaminated clothing and wash before reuse. |
P363 | Wash contaminated clothing before reuse. |
P370 | In case of fire: |
P371 | In case of major fire and large quantities: |
P372 | Explosion risk in case of fire. |
P373 | DO NOT fight fire when fire reaches explosives. |
P374 | Fight fire with normal precautions from a reasonable distance. |
P376 | Stop leak if safe to do so. Oxidising gases (section 2.4) 1 |
P377 | Leaking gas fire: Do not extinguish, unless leak can be stopped safely. |
P378 | |
P380 | Evacuate area. |
P381 | Eliminate all ignition sources if safe to do so. |
P390 | Absorb spillage to prevent material damage. |
P391 | Collect spillage. Hazardous to the aquatic environment |
P301 + P310 | IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
P301 + P312 | IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
P301 + P330 + P331 | IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. |
P302 + P334 | IF ON SKIN: Immerse in cool water/wrap in wet bandages. |
P302 + P350 | IF ON SKIN: Gently wash with plenty of soap and water. |
P303 + P361 + P353 | IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. |
P304 + P312 | IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell. |
P304 + P340 | IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. |
P304 + P341 | IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P305 + P351 + P338 | IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
P306 + P360 | IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes. |
P307 + P311 | IF exposed: call a POISON CENTER or doctor/physician. |
P308 + P313 | IF exposed or concerned: Get medical advice/attention. |
P309 + P311 | IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician. |
P332 + P313 | IF SKIN irritation occurs: Get medical advice/attention. |
P333 + P313 | IF SKIN irritation or rash occurs: Get medical advice/attention. |
P335 + P334 | Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages. |
P337 + P313 | IF eye irritation persists: Get medical advice/attention. |
P342 + P311 | IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. |
P370 + P376 | In case of fire: Stop leak if safe to Do so. |
P370 + P378 | In case of fire: |
P370 + P380 | In case of fire: Evacuate area. |
P370 + P380 + P375 | In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion. |
P371 + P380 + P375 | In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion. |
Storage | |
Code | Phrase |
P401 | |
P402 | Store in a dry place. |
P403 | Store in a well-ventilated place. |
P404 | Store in a closed container. |
P405 | Store locked up. |
P406 | Store in corrosive resistant/ container with a resistant inner liner. |
P407 | Maintain air gap between stacks/pallets. |
P410 | Protect from sunlight. |
P411 | |
P412 | Do not expose to temperatures exceeding 50 oC/ 122 oF. |
P413 | |
P420 | Store away from other materials. |
P422 | |
P402 + P404 | Store in a dry place. Store in a closed container. |
P403 + P233 | Store in a well-ventilated place. Keep container tightly closed. |
P403 + P235 | Store in a well-ventilated place. Keep cool. |
P410 + P403 | Protect from sunlight. Store in a well-ventilated place. |
P410 + P412 | Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF. |
P411 + P235 | Keep cool. |
Disposal | |
Code | Phrase |
P501 | Dispose of contents/container to ... |
P502 | Refer to manufacturer/supplier for information on recovery/recycling |
Physical hazards | |
Code | Phrase |
H200 | Unstable explosive |
H201 | Explosive; mass explosion hazard |
H202 | Explosive; severe projection hazard |
H203 | Explosive; fire, blast or projection hazard |
H204 | Fire or projection hazard |
H205 | May mass explode in fire |
H220 | Extremely flammable gas |
H221 | Flammable gas |
H222 | Extremely flammable aerosol |
H223 | Flammable aerosol |
H224 | Extremely flammable liquid and vapour |
H225 | Highly flammable liquid and vapour |
H226 | Flammable liquid and vapour |
H227 | Combustible liquid |
H228 | Flammable solid |
H229 | Pressurized container: may burst if heated |
H230 | May react explosively even in the absence of air |
H231 | May react explosively even in the absence of air at elevated pressure and/or temperature |
H240 | Heating may cause an explosion |
H241 | Heating may cause a fire or explosion |
H242 | Heating may cause a fire |
H250 | Catches fire spontaneously if exposed to air |
H251 | Self-heating; may catch fire |
H252 | Self-heating in large quantities; may catch fire |
H260 | In contact with water releases flammable gases which may ignite spontaneously |
H261 | In contact with water releases flammable gas |
H270 | May cause or intensify fire; oxidizer |
H271 | May cause fire or explosion; strong oxidizer |
H272 | May intensify fire; oxidizer |
H280 | Contains gas under pressure; may explode if heated |
H281 | Contains refrigerated gas; may cause cryogenic burns or injury |
H290 | May be corrosive to metals |
Health hazards | |
Code | Phrase |
H300 | Fatal if swallowed |
H301 | Toxic if swallowed |
H302 | Harmful if swallowed |
H303 | May be harmful if swallowed |
H304 | May be fatal if swallowed and enters airways |
H305 | May be harmful if swallowed and enters airways |
H310 | Fatal in contact with skin |
H311 | Toxic in contact with skin |
H312 | Harmful in contact with skin |
H313 | May be harmful in contact with skin |
H314 | Causes severe skin burns and eye damage |
H315 | Causes skin irritation |
H316 | Causes mild skin irritation |
H317 | May cause an allergic skin reaction |
H318 | Causes serious eye damage |
H319 | Causes serious eye irritation |
H320 | Causes eye irritation |
H330 | Fatal if inhaled |
H331 | Toxic if inhaled |
H332 | Harmful if inhaled |
H333 | May be harmful if inhaled |
H334 | May cause allergy or asthma symptoms or breathing difficulties if inhaled |
H335 | May cause respiratory irritation |
H336 | May cause drowsiness or dizziness |
H340 | May cause genetic defects |
H341 | Suspected of causing genetic defects |
H350 | May cause cancer |
H351 | Suspected of causing cancer |
H360 | May damage fertility or the unborn child |
H361 | Suspected of damaging fertility or the unborn child |
H361d | Suspected of damaging the unborn child |
H362 | May cause harm to breast-fed children |
H370 | Causes damage to organs |
H371 | May cause damage to organs |
H372 | Causes damage to organs through prolonged or repeated exposure |
H373 | May cause damage to organs through prolonged or repeated exposure |
Environmental hazards | |
Code | Phrase |
H400 | Very toxic to aquatic life |
H401 | Toxic to aquatic life |
H402 | Harmful to aquatic life |
H410 | Very toxic to aquatic life with long-lasting effects |
H411 | Toxic to aquatic life with long-lasting effects |
H412 | Harmful to aquatic life with long-lasting effects |
H413 | May cause long-lasting harmful effects to aquatic life |
H420 | Harms public health and the environment by destroying ozone in the upper atmosphere |
Sorry,this product has been discontinued.
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