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Chemical Structure| 1097917-15-1 Chemical Structure| 1097917-15-1
Chemical Structure| 1097917-15-1

*Storage: Keep in dark place,Inert atmosphere,2-8°C.

ASP3026

CAS No.: 1097917-15-1

ASP3026 is a selective inhibitor for ALK with IC50 of 3.5 nM.

4.5 *For Research Use Only !

Cat. No.: A874603 Purity: 98+%

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Product Details of [ ASP3026 ]

CAS No. :1097917-15-1
Formula : C29H40N8O3S
M.W : 580.75
SMILES Code : O=S(C1=CC=CC=C1NC2=NC=NC(NC3=CC=C(N4CCC(N5CCN(C)CC5)CC4)C=C3OC)=N2)(C(C)C)=O
MDL No. :MFCD21609265
InChI Key :MGGBYMDAPCCKCT-UHFFFAOYSA-N
Pubchem ID :25134326

Safety of [ ASP3026 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Biological Activity

Target
  • ALK

    ALK, IC50:3.5 nM

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT01284192 Advanced Malignancies|Positive... More >> for Anaplastic Lymphoma Kinase|Positive for Proto-Oncogene Tyrosine-Protein Kinase ROS|Solid Tumor|B-Cell Lymphoma Less << PHASE1 COMPLETED 2025-03-16 Site US160, Orange, California... More >>, 92868, United States|Site US184, Sacramento, California, 95817, United States|Site US11, Chicago, Illinois, 60637, United States|Site US2688, Detroit, Michigan, 48201, United States|Site US2492, Houston, Texas, 77030, United States|Site US1905, San Antonio, Texas, 78229, United States Less <<
NCT01401504 Solid Tumor PHASE1 COMPLETED 2025-01-14 Kansai, Japan

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.72mL

0.34mL

0.17mL

8.61mL

1.72mL

0.86mL

17.22mL

3.44mL

1.72mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

References

 

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