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Chemical Structure| 107220-28-0 Chemical Structure| 107220-28-0
Chemical Structure| 107220-28-0

*Storage: Inert atmosphere,Store in freezer, under -20°C.

Cevimeline HCl

CAS No.: 107220-28-0

Cevimeline HCl is a parasympathomimetic and muscarinic agonist, with particular effect on M3 receptors and used in the treatment of dry mouth associated with sjogren's syndrome.

Synonyms: AF102B hydrochloride;Cevimeline (hydrochloride);SNK 508

4.5 *For Research Use Only !

Cat. No.: A758181 Purity: 98%

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Product Details of [ Cevimeline HCl ]

CAS No. :107220-28-0
Formula : C10H18ClNOS
M.W : 235.77
SMILES Code : C[C@@H]1O[C@]2(CN3CCC2CC3)CS1.[H]Cl
Synonyms :
AF102B hydrochloride;Cevimeline (hydrochloride);SNK 508
MDL No. :MFCD01961045

Safety of [ Cevimeline HCl ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338
Class:6.1
UN#:2811
Packing Group:

ALK Isoform Comparison

Name AChE AChR mAChR nAChR Purity
Donepezil +++

bAChE, IC50: 8.12 nM

hAChE, IC50: 11.6 nM

98%
Loganin ++

AChE, IC50: 3.95 μM

98%
topride HCl ++

AChE, IC50: 2.04 μM

98%
Dehydroevodiamine HCl 95%
Jatrorrhizine ++

AChE, IC50: 872 nM

98%
(-)-Huperzine A ++++

AChE (G4 form), Ki: 7 nM

98%
Galanthamine HBr ++

AChE, IC50: 0.35 μM

98%
Trospium chloride 99%
Gallamine Triethiodide +

AChR, IC50: 68.0 μM

98%
Hexamethonium Bromide 99%
Neostigmine bromide 98%
Oxybutynin 98%
Irsogladine 99%
Pyridostigmine bromide 99+%
Rivastigmine +

AChR, IC50: 5.5 μM

98%
Tropicamide +++

M4 mAChR, IC50: 8 nM

98%
Diphenmanil methylsulfate 99%
Umeclidinium bromide 95%
Otilonium bromide 98%
Flavoxate HCl +

mAChR, IC50: 12.2 μM

99%
Ipratropium bromide 98%
Diphenidol HCl 98%
Darifenacin hydrobromide ++++

M3 mAChR, pKi: 8.9

98%
Aclidinium Bromide ++++

M2 mAChR, Ki: 0.1 nM

M4 mAChR, Ki: 0.21 nM

98%
Oxybutynin chloride 99%
Solifenacin 98%
Benzethonium chloride +++

α4β2 nAChRs, IC50: 49 nM

α7 nAChRs, IC50: 122 nM

99+%
PNU-120596 ++

α7 nAChR, EC50: 216 nM

99+%

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

4.24mL

0.85mL

0.42mL

21.21mL

4.24mL

2.12mL

42.41mL

8.48mL

4.24mL

References

 

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