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Chemical Structure| 22862-76-6 Chemical Structure| 22862-76-6
Chemical Structure| 22862-76-6

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Anisomycin

CAS No.: 22862-76-6

Anisomycin is a naturally occuring antibiotic which can act as a potent activator of stress-activated protein kinases (JNK/SAPK) and p38 MAPK, and also can inhibit protein synthesis by blocking translation.

Synonyms: Flagecidin;Wuningmeisu C;AI3-50846;NSC 76712

4.5 *For research use only!

Cat. No.: A646979 Purity: 98%

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Product Details of [ Anisomycin ]

CAS No. :22862-76-6
Formula : C14H19NO4
M.W : 265.31
Synonyms :
Flagecidin;Wuningmeisu C;AI3-50846;NSC 76712
MDL No. :MFCD00077650
InChI Key :YKJYKKNCCRKFSL-RDBSUJKOSA-N
Pubchem ID :253602

Safety of [ Anisomycin ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of [ Anisomycin ]

MAPK
TLR

ALK Isoform Comparison

Name JNK JNK1 JNK2 JNK3 Purity
Mulberroside A 98%
Loureirin B 99%
Ginsenoside Re 98%
(+)-(3R,8S)-Falcarindiol 99%
Urolithin B 95%
Astragaloside IV 98%
NDMC101 98%
DB07268 ++++

JNK1, IC50: 9 nM

98%
SP600125 +

MKK4, IC50: 0.4 μM

+++

JNK1, IC50: 40 nM

+++

JNK2, IC50: 40 nM

+++

JNK3, IC50: 90 nM

98%
JNK-IN-7 ++++

JNK1, IC50: 1.5 nM

++++

JNK2, IC50: 2 nM

++++

JNK3, IC50: 0.7 nM

99%
JNK-IN-8 ++++

JNK1, IC50: 4.7 nM

+++

JNK2, IC50: 18.7 nM

++++

JNK3, IC50: 1 nM

98%
3,3',5-Triiodo-L-thyronine ++

JNK1, Kd: 240 nM

++

JNK2, Kd: 290 nM

+++

JNK3, Kd: 66 nM

98%
IQ-1S free acid +

JNK1, IC50: 390 nM

++

JNK2, IC50: 360 nM

+++

JNK3, IC50: 87 nM

99%
BI-78D3 ++

JNK, IC50: 280 nM

++

JNK, IC50: 280 nM

++

JNK, IC50: 280 nM

++

JNK, IC50: 280 nM

98%
Bentamapimod +++

JNK1, IC50: 80 nM

+++

JNK2, IC50: 90 nM

++

JNK3, IC50: 230 nM

98%
Resveratrol +

JNK1, IC50: 50 μM

98%
Indirubin-3′-oxime 98%
SU3327 +

JNK, IC50: 0.7 μM

+

JNK, IC50: 0.7 μM

+

JNK, IC50: 0.7 μM

+

JNK, IC50: 0.7 μM

98% HPLC
JNK Inhibitor VIII ++++

JNK1, IC50: 45 nM

JNK1, Ki: 2 nM

++++

JNK2, IC50: 160 nM

JNK2, Ki: 4 nM

+++

JNK3, Ki: 52 nM

98%
Doramapimod 99%
RPI-1 99%
TCS JNK 5a ++

JNK2, pIC50: 6.5

++

JNK3, pIC50: 6.7

98%
SP 600125, negative control +

JNK2, IC50: 18 μM

+

JNK3, IC50: 24 μM

97%

Protocol

Bio Calculators
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