Chemistry Heterocyclic Building Blocks Piperidines piperidin-3-ol
Oxidation: The alcohol group can be oxidized to form the corresponding aldehyde or carboxylic acid under appropriate conditions.
Esterification: The hydroxyl group can react with carboxylic acids or acid derivatives to form esters through esterification reactions.
Ether Formation: The alcohol group can undergo nucleophilic substitution reactions with alky halides or sulfonates to form ethers.
Nucleophilic Substitution: The alcohol group can undergo nucleophilic substitution reactions with various electrophiles, leading to the formation of ether, ester, or other functionalized derivatives.
Reduction: The alcohol group can be reduced to the corresponding alkane using reducing agents such as lithium aluminum hydride or sodium borohydride.
Protection Reactions: The alcohol group can be protected using protecting groups such as tert-butyldimethylsilyl (TBDMS) or tert-butyldiphenylsilyl (TBDPS) groups.
Condensation Reactions: It can participate in condensation reactions with carbonyl compounds or other nucleophiles to form cyclic compounds or larger molecules.
Acid-Catalyzed Reactions: The alcohol group can undergo various acid-catalyzed reactions, such as dehydration to form alkenes or rearrangement reactions.
Framework+−
By Key Group+−
By Parent Nucleus+−
By Functional Group+−
Heterocyclic related+−
Formula Weight+−
click to sign in and save
tert-Butyl 4-fluoro-3-hydroxypiperidine-1-carboxylate
click to sign in and save
tert-Butyl (3R,4S)-4-fluoro-3-hydroxypiperidine-1-carboxylate
click to sign in and save
trans-tert-Butyl 4-fluoro-3-hydroxypiperidine-1-carboxylate
click to sign in and save
tert-Butyl ((3R,4S)-3-hydroxypiperidin-4-yl)carbamate
click to sign in and save
tert-Butyl ((3S,4S)-3-hydroxypiperidin-4-yl)carbamate
click to sign in and save
tert-Butyl 3-hydroxypiperidine-1-carboxylate
click to sign in and save
(3S,4R)-tert-Butyl 4-fluoro-3-hydroxypiperidine-1-carboxylate
click to sign in and save
tert-Butyl 3-hydroxy-4-methylpiperidine-1-carboxylate
click to sign in and save
(3S,4R)-tert-Butyl 4-amino-3-hydroxypiperidine-1-carboxylate
click to sign in and save
(3R,4R)-tert-Butyl 4-amino-3-hydroxypiperidine-1-carboxylate
click to sign in and save
tert-Butyl 4,4-difluoro-3-hydroxypiperidine-1-carboxylate
click to sign in and save
4,4-Difluoropiperidin-3-ol hydrochloride
click to sign in and save
1-(tert-Butoxycarbonyl)-3-hydroxypiperidine-4-carboxylic acid
click to sign in and save
tert-Butyl 3-hydroxy-4,4-dimethoxypiperidine-1-carboxylate
click to sign in and save
1-tert-Butyl 4-ethyl 3-hydroxypiperidine-1,4-dicarboxylate