[ CAS No. 2280-44-6 ] (3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol

,98+%

Cat. No.: A607126

2D 3D

Structure of 2280-44-6

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Quality Control of [ 2280-44-6 ]

COA NMR CNMR HPLC LC-MS

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Specification

Alternatived Products of [ 2280-44-6 ]

Product Details of [ 2280-44-6 ]

CAS No. :	2280-44-6	MDL No. :	MFCD00063684
Formula :	C₆H₁₂O₆	Boiling Point :	-
Linear Structure Formula :	(CHOH)₄CHCH₂OHO	InChI Key :	-
M.W :	180.16	Pubchem ID :	-
Synonyms :

Safety of [ 2280-44-6 ]

Signal Word:	Warning	Class:	N/A
Precautionary Statements:	P264-P270-P273-P301+P312+P330-P501	UN#:	N/A
Hazard Statements:	H302-H412	Packing Group:	N/A
GHS Pictogram:

Application In Synthesis of [ 2280-44-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Upstream synthesis route of [ 2280-44-6 ]
Downstream synthetic route of [ 2280-44-6 ]

[ 2280-44-6 ] Synthesis Path-Upstream 1~5

1
[ 2280-44-6 ]
[ 501-94-0 ]
[ 10338-51-9 ]

Reference： [1] Asian Journal of Chemistry, 2013, vol. 25, # 9, p. 5095 - 5098

2
[ 26544-34-3 ]
[ 2280-44-6 ]
[ 30738-01-3 ]
[ 139759-42-5 ]
[ 578-74-5 ]

Reference： [1] Liebigs Annalen der Chemie, 1992, # 6, p. 575 - 580

3
[ 26544-34-3 ]
[ 2280-44-6 ]
[ 520-36-5 ]
[ 139759-42-5 ]
[ 578-74-5 ]

Reference： [1] Liebigs Annalen der Chemie, 1992, # 6, p. 575 - 580

4
[ 57-50-1 ]
[ 2280-44-6 ]
[ 470-69-9 ]
[ 13133-07-8 ]

Reference： [1] Tetrahedron Asymmetry, 2016, vol. 27, # 24, p. 1245 - 1252

5
[ 57-50-1 ]
[ 2280-44-6 ]
[ 59432-60-9 ]
[ 470-69-9 ]
[ 13133-07-8 ]

Reference： [1] Carbohydrate Research, 2008, vol. 343, # 1, p. 56 - 66

[ 2280-44-6 ] Synthesis Path-Downstream 1~18

1
[ 2280-44-6 ]
[ 657-27-2 ]
[ 88-14-2 ]
[ 6338-41-6 ]
5-(3,4,5,6-tetrahydropyrid-3-ylidenemethyl)-2-furanmethanol [ No CAS ]
1-deoxy-1-(N⁶-lysino)-D-fructose [ No CAS ]
(+/-)-2-formyl-5-(hydroxymethyl)pyrrole-1-norleucine [ No CAS ]
[ 34371-14-7 ]

Reference： [1]Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry,1984,vol. 38,p. 689 - 694

2
[ 64-17-5 ]
[ 182698-28-8 ]
[ 2280-44-6 ]
[ 628-97-7 ]

Reference： [1]Journal of Carbohydrate Chemistry,1994,vol. 13,p. 249 - 272

3
[ 104777-68-6 ]
[ 2280-44-6 ]

Reference： [1]Phytochemistry,1986,vol. 25,p. 1633 - 1636

4
[ 89759-25-1 ]
[ 2280-44-6 ]
[ 28697-53-2 ]
[ 491-71-4 ]

Reference： [1]Chemistry of Natural Compounds,1983,vol. 19,p. 746 - 747
Khimiya Prirodnykh Soedinenii,1983,p. 783 - 784

5
chrysoeriol-7-O-β-D-(3''-E-p-coumaroyl)-glucopyranoside [ No CAS ]
[ 2280-44-6 ]
[ 7400-08-0 ]
[ 491-71-4 ]

Reference： [1]Phytochemistry,1986,vol. 25,p. 1253 - 1254

6
[ 520-26-3 ]
[ 2280-44-6 ]
[ 73-34-7 ]
hesperetin 7‐O‐β‐D‐glucopyranoside [ No CAS ]
[ 520-33-2 ]

Reference： [1]Carbohydrate Research,2000,vol. 328,p. 141 - 146

7
[ 529-59-9 ]
[ 2280-44-6 ]
[ 446-72-0 ]

Reference： [1]Phytochemistry,2001,vol. 58,p. 995 - 1005

8
[ 2280-44-6 ]
[ 555-30-6 ]
N-(1'-deoxy-β-D-fructopyranos-1'-yl)-L-α-methyldopa [ No CAS ]
(1R,1S',S,3S)-1-(D-glucopentitol-1'-yl)-3-carboxy-3-methyl-7,8-dihydroxy-1,2,3,4-tetrahydroisoquinoline [ No CAS ]
(1R,1S',S,3S)-1-(D-glucopentitol-1'-yl)-3-carboxy-3-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline [ No CAS ]
(1S,1S',S,3S)-1-(D-glucopentitol-1'-yl)-3-carboxy-3-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline [ No CAS ]

Reference： [1]Carbohydrate Research,2005,vol. 340,p. 2719 - 2727

9
[ 2280-44-6 ]
[ 492-30-8 ]

Reference： [1]Tetrahedron Letters,2006,vol. 47,p. 315 - 318
[2]Tetrahedron Letters,2006,vol. 47,p. 315 - 318

10
[ 57-50-1 ]
[ 2280-44-6 ]
[ 59432-60-9 ]
[ 470-69-9 ]
[ 13133-07-8 ]

Reference： [1]Carbohydrate Research,2008,vol. 343,p. 56 - 66

11
[ 2280-44-6 ]
[ 623-05-2 ]
[ 15887-38-4 ]
[ 62499-27-8 ]

Reference： [1]Tetrahedron Asymmetry,2010,vol. 21,p. 2060 - 2065

12
[ 18524-94-2 ]
[ 2280-44-6 ]

Reference： [1]Oriental Journal of Chemistry,2012,vol. 28,p. 1011 - 1013,3

13
[ 2280-44-6 ]
[ 137215-27-1 ]
4-methylumbelliferyl 1-thio-β-D-glucopyranoside [ No CAS ]

Reference： [1]Chemistry Letters,2013,vol. 42,p. 1038 - 1039

14
20R,24S-epoxycycloartane-3β,6α,16β,25-tetraol 3-O-[β-D-glucopyranosyl(1→2)]-β-D-glucopyranoside-25-O-β-D-glucopyranoside [ No CAS ]
[ 2280-44-6 ]
[ 84605-18-5 ]

Reference： [1]Chemistry of Natural Compounds,2013,vol. 49,p. 475 - 477
Khim. Prir. Soedin.,2013,p. 405 - 407,3

15
[ 2280-44-6 ]
[ 1570-05-4 ]
β-D-glucopyranose-1,2,3,4,6-pentakis[3,4-bis(phenylmethoxy)benzoate] [ No CAS ]
α-D-glucopyranose-1,2,3,4,6-pentakis[3,4-bis(phenylmethoxy)benzoate] [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 40℃;	General procedure: A suspension of D-glucose (0.03 g,0.16 mmol), 4-(benzyloxy)-3-methoxybenzoic acid (0.34 g,1.30 mmol), dicyclohexylcarbodiimide (DCC) (0.28 g, 1.32 mmol) andN,N-(di-methylamino) pyridine (DMAP) (0.16 g, 1.36 mmol) in freshlydistilled dichloromethane (DCM) was refluxed for 16?18 hrs (monitoredby TLC). After cooling reaction mixture at room temperature,urea by-product was removed by gravity filtration and the filtratewas evaporated. Compound 11 was purified by column chromatographyeluting with a mixture of dichloromethane, hexane, andethyl acetate. The product was collected, evaporated and precipitatedusing toluene and cyclohexane

Reference： [1]Carbohydrate Research,2016,vol. 430,p. 72 - 81

16
[ 57-50-1 ]
[ 2280-44-6 ]
[ 470-69-9 ]
[ 13133-07-8 ]

Yield	Reaction Conditions	Operation in experiment
	With sodium dihydrogenphosphate; citric acid; In water; at 37℃; for 24h;pH 7.0;Microbiological reaction;Kinetics;	Transfructosylation reactions were carried out using uninduced,inulin-induced and sucrose-induced cells in a reaction volumeof 5 ml. The reaction mixture contained 100 mg lyophilizedcells and 10% (w/v) sucrose in 5 ml phosphate citrate buffer (pH7.0). The mixture was incubated at 37 C for 24 h at 220 rpm in areciprocating shaker (SI-300R Jeo Tech). At the end of the reaction,cells were separated out by centrifugation and the vials heated in aboiling water bath. The clear supernatant was analysed for residualsucrose, glucose and synthesized fructo-oligosaccharides

Reference： [1]Tetrahedron Asymmetry,2016,vol. 27,p. 1245 - 1252

17
[ 2280-44-6 ]
[ 1743-60-8 ]
R_. oryzae AS 3.2380 fungus cells [ No CAS ]
[ 31299-96-4 ]

Yield	Reaction Conditions	Operation in experiment
	In water; acetone; for 24h;pH 7.0;Microbiological reaction;	General procedure: All of the filamentous fungi were pre-incubated in potato medium to get enough fungi cells. The glucosylation medium was sodium phosphate buffer: 13.62 g NaH2PO4, 2.36 g NaOH, and 20 g D-glucose in1000 mL water. 1.5 g R. oryzae AS 3.2380 fungus cells were preincubatedin the glucosylation medium (200 mL), 30 °C, 130 rpm for12 h. Then, estrogen substrates (10 mg) dissolved in acetone were injected into the medium with the continued incubation for 24 h [19].When the fungus cells were filtered, the incubation culture was subjected to a MCI (Middle chromatogram isolated gel) column, which was eluted by 30percent ethanol aqueous, 50percent ethanol aqueous, and 95percentethanol, successively. The estrogen 3beta-glucosides could be obtained in the 50percent ethanol aqueous elution with the purity > 95percent.

Reference： [1]Catalysis Communications,2017,vol. 97,p. 106 - 110

18
[ 1004-38-2 ]
[ 2280-44-6 ]
C₁₀H₁₇N₅O₅ [ No CAS ]
C₁₀H₁₇N₅O₅ [ No CAS ]
C₁₀H₁₇N₅O₅ [ No CAS ]

Reference： [1]Organic and Biomolecular Chemistry,2018,vol. 16,p. 1263 - 1271

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P304 + P341	IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
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P308 + P313	IF exposed or concerned: Get medical advice/attention.
P309 + P311	IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P332 + P313	IF SKIN irritation occurs: Get medical advice/attention.
P333 + P313	IF SKIN irritation or rash occurs: Get medical advice/attention.
P335 + P334	Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.
P337 + P313	IF eye irritation persists: Get medical advice/attention.
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[ CAS No. 2280-44-6 ] (3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol

Quality Control of [ 2280-44-6 ]

Related Doc. of [ 2280-44-6 ]

Product Details of [ 2280-44-6 ]

Safety of [ 2280-44-6 ]

Application In Synthesis of [ 2280-44-6 ]

[ 2280-44-6 ] Synthesis Path-Upstream 1~5

[ 2280-44-6 ] Synthesis Path-Downstream 1~18

Precautionary Statements-General

Prevention

Response

Storage

Disposal

Physical hazards

Health hazards

Environmental hazards

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