Beckmann Rearrangement

The Beckmann rearrangement is a chemical reaction that converts an oxime functional group into substituted amides. It is effectively applied to haloimines and nitrones, yielding lactams when cyclic oximes and haloimines are involved.

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[1]Wang J, Jiang X, Shi A, et al. Application of Reaction-Extraction Coupling Technology: Highly Efficient Preparation of ε-Caprolactam over A Deep Eutectic Solvent under Mild Reaction Conditions[J]. ACS Sustainable Chem. Eng., 2024, 12(2): 1095-1103.

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