Alternatived Products of [ 78302-27-9 ]
Product Details of [ 78302-27-9 ]
CAS No. : | 78302-27-9 |
MDL No. : | MFCD09906532 |
Formula : |
C9H7Cl2NO
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Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
216.06
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Pubchem ID : | - |
Synonyms : |
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Safety of [ 78302-27-9 ]
Signal Word: | |
Class: | |
Precautionary Statements: | |
UN#: | |
Hazard Statements: | |
Packing Group: | |
Application In Synthesis of [ 78302-27-9 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 78302-27-9 ]
- 1
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[ 78302-27-9 ]
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[ 107-15-3 ]
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[ 21498-08-8 ]
Yield | Reaction Conditions | Operation in experiment |
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With hydrogenchloride; carbon disulfide; ammonia 1) toluene, reflux, 2) propan-2-ol; Yield given. Multistep reaction; |
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- 2
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[ 78302-27-9 ]
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[ 107-15-3 ]
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[ 31036-80-3 ]
Yield | Reaction Conditions | Operation in experiment |
60% |
With carbon disulfide; ammonia In toluene Heating; |
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With hydrogenchloride In ethanol; chloroform |
2 (-)-2-[1-(2,6-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene
(-)-2-[1-(2,6-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene 20.0 g (=0.0925 mols) of (-)-2-(2,6-dichlorophenoxy)-propionitrile are converted into (-)-2-(2,6-dichlorophenoxy)-propionimido acid ethylester-hydrochloride at 0° C. with 4.3 g (=0.0925 mols) of ethanol in 50 ml of absolute chloroform by introducing hydrogen chloride. This product is then dissolved in 20 ml of ethanol after removing the solvent under vacuum at 20° C. and is cyclised with 6.0 g (0.1 mol) of 1,2-diaminoethane into (-)-2-[1-(2,6-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene C11 H12 Cl2 Hn O [259.1]. After working up, 16 g of product are obtained. Mp. 127°-128° C.: [α]D20 =-80.7° (c=1/ethanol). |
- 3
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[ 78302-27-9 ]
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[ 31036-80-3 ]
Yield | Reaction Conditions | Operation in experiment |
|
With hydrogenchloride In ethanol; chloroform |
2 (+)-2-[1-(2,6-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene
(+)-2-[1-(2,6-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene 22.0 g (=0.1018 mols) of (+)-2-(2,6-dichlorophenoxy)-propionitrile are converted into (+)-2-(2,6-dichlorophenoxy)-propionimido acid ethylester-hydrochloride at 0° C. with 4.7 g (=0.1018 mols) of ethanol in 50 ml of absolute chloroform by intoducing hydrogen chloride. This product is then dissolved in 20 ml of ethanol after removing the solvent under vacuum at 20° C. and is cyclised with 6.6 g (=0.11 mol) of 1,2-diaminoethane into (+)-2-[1-(2,6-dichlorophenoxy)ethyl]-1,3-diazacyclopent-2-ene C11 H12 Cl2 N2 O [259.1]. After working up, 17 g of product are obtained. Mp. 128° C. [α]D20 =+80.4° (c=1/ethanol) |