Home Cart 0 Sign in  

[ CAS No. 623142-96-1 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 623142-96-1
Chemical Structure| 623142-96-1
Structure of 623142-96-1 * Storage: {[proInfo.prStorage]}
Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Quality Control of [ 623142-96-1 ]

Related Doc. of [ 623142-96-1 ]

Alternatived Products of [ 623142-96-1 ]

Product Details of [ 623142-96-1 ]

CAS No. :623142-96-1 MDL No. :MFCD12024693
Formula : C24H24N4O5S Boiling Point : -
Linear Structure Formula :- InChI Key :SHPFDGWALWEPGS-UHFFFAOYSA-N
M.W : 480.54 Pubchem ID :9869779
Synonyms :

Safety of [ 623142-96-1 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H302-H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 623142-96-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 623142-96-1 ]

[ 623142-96-1 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 32315-10-9 ]
  • [ 432047-36-4 ]
  • Ki20227 [ No CAS ]
YieldReaction ConditionsOperation in experiment
72% Example 74: N-{4-[(6,7-Dimethoxy-4-quinolyl)oxy]-2-methoxyphenyl}-N'-[1-(1,3-thiazol-2-yl)ethyl]urea 4-[(6,7-Dimethoxy-4-quinolyl)oxy]-2-methoxyaniline (816 mg) was dissolved in chloroform (40 ml) and triethylamine (2.0 ml) to prepare a solution. A solution of triphosgene (368 mg) in chloroform (1.0 ml) was then added to the solution, and the mixture was stirred at room temperature for one hr. Next, a solution of <strong>[432047-36-4]1-(1,3-thiazol-2-yl)-1-ethylamine</strong> (352 mg) in chloroform (1.0 ml) was added thereto, and the mixture was stirred at room temperature overnight. Water (40 ml) was added thereto, and the mixture was stirred for 10 min, followed by extraction with chloroform. The organic layer was washed with saturated brine and was dried over sodium sulfate. The solvent was removed by evaporation, and the residue was purified by chromatography on silica gel using chloroform/acetone for development to give the title compound (860 mg, 72%). 1H-NMR (CDCl3, 400 MHz): delta 1.69 (d, J = 6.8 Hz, 3H), 3.83 (s, 3H), 4.06 (s, 3H), 4.07 (s, 3H), 5.37 - 5.45 (m, 1H), 5.67 (d, J = 7.3 Hz, 1H), 6.51 (d, J = 5.4 Hz, 1H), 6.70 (d, J = 2.4 Hz, 1H), 6.79 (dd, J = 2.4, 8.8 Hz, 1H), 7.02 (s, 1H), 7.30 (d, J = 3.4 Hz, 1H), 7.53 (s, 1H), 7.57 (s, 1H), 7.73 (d, J = 3.4 Hz, 1H), 8.19 (d, J = 8.8 Hz, 1H), 8.47 (d, J = 5.4 Hz, 1H)
  • 2
  • [ 24295-03-2 ]
  • [ 623142-96-1 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 1.1: pyridine; hydroxylamine hydrochloride / ethanol / 20 °C 2.1: ammonium chloride; zinc / methanol / 2 h / Heating / reflux 3.1: triethylamine / chloroform / 1 h / 20 °C 3.2: 20 °C
  • 3
  • [ 944993-06-0 ]
  • [ 623142-96-1 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1.1: ammonium chloride; zinc / methanol / 2 h / Heating / reflux 2.1: triethylamine / chloroform / 1 h / 20 °C 2.2: 20 °C
Same Skeleton Products
Historical Records