[ CAS No. 5856-77-9 ] {[proInfo.proName]}

Name: 5856-77-9|2,2-Dimethylbutyrylchloride|98%
Brand: Ambeed
SKU: A365598
Rating: 97 (30 reviews)

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Quality Control of [ 5856-77-9 ]

COA NMR CNMR HPLC LC-MS

Related Doc. of [ 5856-77-9 ]

SDS Specification

Alternatived Products of [ 5856-77-9 ]

Product Details of [ 5856-77-9 ]

CAS No. :	5856-77-9	MDL No. :	MFCD03093071
Formula :	C₆H₁₁ClO	Boiling Point :	-
Linear Structure Formula :	-	InChI Key :	LDJUYMIFFNTKOI-UHFFFAOYSA-N
M.W :	134.60	Pubchem ID :	79958
Synonyms :

Calculated chemistry of [ 5856-77-9 ]

Physicochemical Properties

Num. heavy atoms :	8
Num. arom. heavy atoms :	0
Fraction Csp3 :	0.83
Num. rotatable bonds :	2
Num. H-bond acceptors :	1.0
Num. H-bond donors :	0.0
Molar Refractivity :	35.69
TPSA :	17.07 Å²

Pharmacokinetics

GI absorption :	High
BBB permeant :	Yes
P-gp substrate :	No
CYP1A2 inhibitor :	No
CYP2C19 inhibitor :	No
CYP2C9 inhibitor :	No
CYP2D6 inhibitor :	No
CYP3A4 inhibitor :	No
Log Kp (skin permeation) :	-5.32 cm/s

Lipophilicity

Log Po/w (iLOGP) :	2.04
Log Po/w (XLOGP3) :	2.53
Log Po/w (WLOGP) :	2.19
Log Po/w (MLOGP) :	1.74
Log Po/w (SILICOS-IT) :	1.72
Consensus Log Po/w :	2.04

Druglikeness

Lipinski :	0.0
Ghose :	None
Veber :	0.0
Egan :	0.0
Muegge :	2.0
Bioavailability Score :	0.55

Water Solubility

Log S (ESOL) :	-2.14
Solubility :	0.983 mg/ml ; 0.0073 mol/l
Class :	Soluble
Log S (Ali) :	-2.54
Solubility :	0.393 mg/ml ; 0.00292 mol/l
Class :	Soluble
Log S (SILICOS-IT) :	-2.03
Solubility :	1.26 mg/ml ; 0.0094 mol/l
Class :	Soluble

Medicinal Chemistry

PAINS :	0.0 alert
Brenk :	1.0 alert
Leadlikeness :	1.0
Synthetic accessibility :	1.38

Safety of [ 5856-77-9 ]

Signal Word:	Danger	Class:	8,3
Precautionary Statements:	P210-P233-P234-P240-P241+P242+P243-P260-P264-P280-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P370+P378-P390-P403+P235-P405-P406-P501	UN#:	2920
Hazard Statements:	H225-H290-H314	Packing Group:	Ⅱ
GHS Pictogram:

Application In Synthesis of [ 5856-77-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Upstream synthesis route of [ 5856-77-9 ]
Downstream synthetic route of [ 5856-77-9 ]

[ 5856-77-9 ] Synthesis Path-Upstream 1~1

1
[ 2935-90-2 ]
[ 5856-77-9 ]
[ 938063-63-9 ]

Yield	Reaction Conditions	Operation in experiment
98.4%	Stage #1: at 10℃; for 0.25 h; Stage #2: With ammonia In dichloromethane at 0 - 65℃; for 1.8 h;	To the reaction vessel was added 40g of 2,2-dimethyl butyryl chloride, and then to the reaction vessel was added dropwise 250ml of dichloromethane, stirred for 15min,After the end of the stirring to the outer jacket of the reactor by adding 15percent ice brine cooling cooling treatment, when the temperature in the reaction vessel was cooled to 10 ° C, the reaction vessel was added 25g of 3-mercapto propionic acid, stirring was continued The temperature is lowered so that 2,2-dimethylbutyryl chloride reacts with 3-mercaptopropionate A to produce methyl α-dimethylbutyryl-S-propionate and hydrogen chloride.When the material in the reaction kettle was cooled to 0 ° C, ammonia gas was introduced into the reaction vessel until the pH in the reaction vessel was 7,Ammonia was stopped, heated to 65 ° C and held for 1.8 h,So that ammonia and hydrogen chloride generated by the reaction, ammonium chloride generated to promote the progress of the reaction until the reaction is completed, the reaction vessel was added 100ml of water,After the addition and stirring 30min, making the reaction of hydrogen chloride fully dissolved in water, and then allowed to stand 4.5h, making the dissolved liquid layering.After the liquid is layered, an aqueous layer and an organic layer are obtained, and the aqueous layer is an aqueous solution of ammonium chloride. The aqueous layer of the aqueous layer is directly transferred or collected by an iron drum to recover the ammonium chloride, and the methylene chloride is recovered by distillation to obtain 55 g Of the crude product, and the recovered methylene chloride solution was recycled,55 g of the crude product was dissolved by heating in 300 ml of ethanol, decolored with activated charcoal, concentrated to 5 ° C and held for 2 h to give 52 g of a mixture, 52 g of the mixture was filtered and washed with 78 g of methylene chloride and finally 48.8 g of product was obtained by drying. The yield of methyl α-dimethylbutyryl-S-propionate was 98.4percent with a purity of more than 99.0percent.
80%	With N-ethyl-N,N-diisopropylamine In Isopropyl acetate at 2 - 25℃; for 2.16 h;	Example 1 Preparation of Methyl 3-(2,2-Dimethylbutanoylthio)propionate (0117) A solution of N,N-diisopropylethylamine (19.9 mL, 120 mmol) and methyl 3-mercaptopropanoate (7.21 60 mmol) in isopropyl acetate (i-PrOAc, 100 mL) was cooled to an internal temperature of 2° C. (brine ice bath). To this vigorously stirred solution was added 2,2-dimethylbutanoyl chloride (8.1 g, 60 mmol) dropwise over 10 min. The resulting suspension was then stirred at 25° C. for 2 h. The reaction was monitored by checking the disappearance of methyl 3-mercaptopropanoate using thin-layer chromatography (TLC) on silica plates. Spots were stained with iodine (eluent: 5percent EtOAc/heptane; R_fof methyl 3-mercaptopropanoate: 0.20). The reaction was then quenched by addition of saturated ammonium chloride (100 mL) followed by i-PrOAc (100 mL) and the resultant mixture was stirred until all solid dissolved. The phases were separated and the organic phase was washed successively with 1percent aqueous hydrochloric acid (100 mL) and then water (2×50 mL). The organic phase was then dried over sodium sulfate, filtered, and concentrated under reduced pressure (45° C. bath, 50 mm Hg) to obtain a crude mixture as a pale yellow liquid. The crude mixture was subjected to column chromatography over silica gel using a heptane to 2percent EtOAc:heptane gradient. Fractions comprising the pure product were combined and concentrated to afford 10.5 g (80percent) of methyl 3-(2,2-dimethylbutanoylthio)propionate.

Reference： [1] Patent: CN105837482, 2016, A, . Location in patent: Paragraph 0031-0034; 0036-0038; 0040-0042; 0044-0046
[2] Patent: US9399785, 2016, B2, . Location in patent: Page/Page column 23

[ 5856-77-9 ] Synthesis Path-Downstream 1~34

1
[ 5856-77-9 ]
[ 506-82-1 ]
[ 20669-04-9 ]

Yield	Reaction Conditions	Operation in experiment
	With benzene

Reference： [1]Stiles; Mayer [Journal of the American Chemical Society, 1959, vol. 81, p. 1497,1503]

2
[ 5856-77-9 ]
[ 161356-05-4 ]
2,2-Dimethyl-butyric acid 4-phenylsulfamoyl-phenyl ester [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With triethylamine In dichloromethane at 25℃;

Reference： [1]Imaki, Katsuhiro; Okada, Takanori; Nakayama, Yoshisuke; Nagao, Yuuki; Kobayashi, Kaoru; Sakai, Yasuhiro; Mohri, Tetsuya; Amino, Takaaki; Nakai, Hisao; Kawamura, Masanori [Bioorganic and Medicinal Chemistry, 1996, vol. 4, # 12, p. 2115 - 2134]

3
[ 5856-77-9 ]
[ 150864-95-2 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 5 steps 1: triphenylphosphine 2: 80 percent / PhI(OAc)2; I₂ / Pd(OAc)2 / CH₂Cl₂ / 24 h / 65 °C 3: 85 percent / benzoyl peroxide / benzene / 2 h / 115 °C 4: 92 percent / H₂SO₄ / dioxane / 15 h / 100 °C

Reference： [1]Giri, Ramesh; Wasa, Masayuki; Breazzano, Steven P.; Yu, Jin-Quan [Organic Letters, 2006, vol. 8, # 25, p. 5685 - 5688]

4
[ 5856-77-9 ]
[ 66943-05-3 ]
1-(2,2-Dimethylbutyroyl)-1-aza-4,7,10,13-tetraoxacyclopentadecane [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
		Example 31 1-(2,2-Dimethylbutyroyl)-1-aza-4,7,10,13-tetraoxacyclopentadecane STR36 Analogously to Example 14 from 1-aza-4,7,10,13-tetraoxacyclopentadecane and 2,2-dimethylbutyryl chloride.

Reference： [1]Patent: US5445762,1995,A

5
[ 98198-48-2 ]
[ 5856-77-9 ]
[ 1029127-90-9 ]

Yield	Reaction Conditions	Operation in experiment
93%	With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 20℃;	[0203] To amine (e.g. 2.1, 10.16 g, 5.432 mmol) in DCM (130 niL) was added NJt- diisopropyl-ethylamine (10.9 niL, 6.25 mmol). The reaction was cooled to 0 C and a solution of acid chloride (e.g. a2, 7.83 mL, 5.70 mmol) was added slowly. The reaction was stirred overnight at room temperature. The reaction was washed with 1 N HCl, saturated NaHCO3 solution, and brine, dried over MgSO4, filtered, the solvent evaporated and the residue was purified by silica gel chromatography using hexane/ethyl acetate eluents; [0211] N-(5-bromo-4-methylpyridin-2-yl)-2,2-dimethylbutanamide 2.2 was prepared from 5- bromo-4-methylpyridin-2-amine 2.1 and 2,2-dimethylbutanoyl chloride a2 following general method A in 93 % yield. MS analysis m/z = 285+1

Reference： [1]Bioorganic and Medicinal Chemistry Letters,2009,vol. 19,p. 5931 - 5935
[2]Patent: WO2008/63625,2008,A2 .Location in patent: Page/Page column 79; 82-83

6
[ 5856-77-9 ]
[ 3163-15-3 ]
[ 1146220-50-9 ]

Reference： [1]Synlett,2009,p. 437 - 440

7
[ 5856-77-9 ]
[ 4506-66-5 ]
[ 1184267-92-2 ]

Reference： [1]Angewandte Chemie - International Edition,2009,vol. 48,p. 5187 - 5190

8
[ 5856-77-9 ]
[ 38186-83-3 ]
[ 1194098-48-0 ]

Reference： [1]Bioorganic and Medicinal Chemistry Letters,2009,vol. 19,p. 5931 - 5935

9
[ 5856-77-9 ]
[ 76456-06-9 ]
[ 1384980-43-1 ]

Reference： [1]Organic Letters,2012,vol. 14,p. 3724 - 3727

10
[ 5856-77-9 ]
[ 52568-28-2 ]
2,2-dimethyl-N-(2-(pyridin-2-yl)propan-2-yl)butanamide [ No CAS ]

Reference： [1]Organic Letters,2015,vol. 17,p. 1200 - 1203

11
[ 5856-77-9 ]
[ 1022150-12-4 ]
(R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-2,2-dimethylbutan-1-one [ No CAS ]

Reference： [1]Journal of Medicinal Chemistry,2015,vol. 58,p. 9625 - 9638

12
[ 30465-68-0 ]
[ 5856-77-9 ]
N-(5-methoxyquinolin-8-yl)-2,2-dimethylbutanamide [ No CAS ]

Reference： [1]Chemical Communications,2016,vol. 52,p. 1242 - 1245

13
[ 5856-77-9 ]
[ 2770-11-8 ]
N-[2-(4-chlorophenoxy)phenyl]-2,2-dimethylbutanamide [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
70%	With triethylamine; In toluene; at 0 - 20℃;	General procedure: To a stirred and cooled solution of <strong>[2770-11-8]2-(4-chlorophenoxy)aniline</strong> (330 mg, 1.50 mmol) and triethylamine (230 muL, 1.65 mmol) in toluene (5 mL), the appropriate acid chloride (pivaloyl chloride, 2,2-dimethylbutyryl chloride, 3-methylbutyryl chloride, propyl chloride, cyclopropanecarbonyl chloride, cyclobutanecarbonyl chloride, methyl succinyl chloride, 4-methoxybenzoyl chloride) (1.65 mmol) was added. Subsequently the reaction mixture was allowed to warm to room temperature. The progress of the reaction was monitored by TLC. After 2-9 h the reaction mixture was extracted with a saturated sodium hydrogen carbonate solution, with a hydrogen chloride solution (10%), with brine and finally with water. Afterwards the organic solution was dried over sodium sulfate and evaporated under reduced pressure. The residue was further purified by recrystallization or column chromatography over silica gel.

Reference： [1]Molecules,2016,vol. 21

14
[ 5856-77-9 ]
[ 37088-66-7 ]
(S)-methyl 3-(2,2-dimethylbutanamido)-3-phenylpropanoate [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
110 mg	With triethylamine; In dichloromethane; at 0 - 20℃; for 4h;Inert atmosphere;	[0501] (S)-3-amino-3-phenylpropanoic acid (lg) was dissolved in methanol (lOmi), lml of thionyl chloride was added at 0°C. The mixture was refluxed for 4h. The solvent was evaporated to dryness and the resulting solid was washed with petroleum ether. The crude product and triethylamine (0.7m1) were dissolved in 15m1 of CH2C12, 2,2-dimethylbutanoylchloride(lg) was added slowly at 0°C under nitrogen. The mixture was stirred at room temperature for 4h. After removal of solvent and purified by silica gel column chromatography to give compound100 (1 10mg, 32percent). 1HNMR(CDCl3,400MHz):7.31-7.35 (m, 2 H), 7.23-7.28 (m, 3 H), 5.40-5.45 (m, 1 H), 3.62 (s, 3 H), 2.87 (m, 2 H), 1.57 (q, 2 H, J = 7.6Hz), 1.19 (s, 3H ),1.18 (s, 3H),0.83 (t, 3 H, J = 7.6 Hz).LC-MS (ESI) [M+H] calad forC16H23NO3, 278.2; found 278.4.

Reference： [1]Patent: WO2016/101885,2016,A1 .Location in patent: Paragraph 0499; 0500; 0501

15
[ 5856-77-9 ]
[ 37088-66-7 ]
(S)-3-(2,2-dimethylbutanamido)-3-phenylpropanoic acid [ No CAS ]

Reference： [1]Patent: WO2016/101885,2016,A1

16
[ 5856-77-9 ]
[ 56613-80-0 ]
(R)-N-(2-hydroxy-1-phenylethyl)-2,2-dimethylbutanamide [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
59.2%	With sodium hydrogencarbonate In tetrahydrofuran; water at 0 - 20℃; for 16h; Inert atmosphere;	[0527] Compound 109: Preparation of (R)-N-(2-hydroxy- 1 -phenylethyl)-2,2- dimethylbutanamide [0529] (R)-2-amino-2-phenylethanol (50 mg, 0.365 mmoL) and NaHCO3 (91.9 mg, 1.094 [0530] mmol) were dissolved in 2 mL of THF/H20 (v/v =1/1).2,2-dimethylbutanoylchloride [0531] (43 mg, 0.398 mmoL) was added slowly to the solution at 0°C under nitrogen. The mixture was stirred at room temperature for 16 h, and extracted with EtOAc (15 mL x 3). The combined organic layers were washed with brine, dried with Na2SO4. Filtered and evaporated to dryness. The residue was purified by column chromatography to give compound 109 as white solid (45mg, 59.2%). 1H NMR: (CDC13, 400 M Hz): (ppm) 7.35-7.39 (m, 2 H), 7.28-7.32 (m, 3 H), 6.26 (brs, 1 H), 5.05-5.09 (m, 1 H), 3.87-3.94 (m, 2 H), 2.70 (brs, 1 H), 1.59 (q, 2 H, J =7.6 Hz), 1.20 (s, 3 H), 1.19 (s, 3 H), 0.87 (t, 3 H, J = 7.6 Hz).LC-MS (ESI) [M+H] calad for C14H21N02, 236.2;found 236.3.

Reference： [1]Current Patent Assignee: NAT INST OF BIOLOGICAL SCIENCES BEIJING; NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES; NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING - WO2016/101885, 2016, A1 Location in patent: Paragraph 0527; 0528; 0529; 0530; 0531

17
[ 5856-77-9 ]
[ 399-30-4 ]
N-(2-fluorobenzyl)-N,2,2-trimethylbutanamide [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
230 mg	With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 0 - 20℃; for 2h;Inert atmosphere;	[0229] Reagent and conditions: (a): (1) CH3NH2.HC1, K2C03, MeOH, rt, 1.Sh; (b): NaBH4 (c) 2, 2-dimethylbutanoyl chloride, DIEA, THF, rt, 2h.[0230] A mixture of K2C03 (207 mg, 1.5 mmoL) and methanamine hydrochloride (202mg, 3.0 mmoL) in 5 mL of MeOH was stirred at room temperature for 30 mm. Then 2- fluorobenzaldehyde (248 mg, 2.0 mmoL) was added to the mixture and stirred at room temperature for 1 h. The mixture was cooled to 0C, and NaBH4 (113.5 mg, 3.0 mmoL) was added in portions. The mixture was stirred at 0C for lh. The solid was filtered and washed with EtOAc. The filtrate was evaporated to dryness and the[0231] residue was dissolved in EtOAc and was washed with water, brine, dried over Na2SO4 The residue was dissolved in lOmL of dry THF. DIEA (264 mg, 2.05 mmoL) was added, 2,2- dimethylbutanoyl chloride (275 mg, 2.05 mmoL) was added slowly to the solution at 0C under nitrogen, then stirred at room temperature for 2 h. 15 mL of water was added to the solution and36extracted with EtOAc (10 mL x 3). The combined organic was washed with 1M HC1, brine, dried with Na2SO4 and concentrated in vacuo. The residue was purified by silica gel column chromatography (PE/EA= 1/2) to give the 230 mg of 1 as a brown solid (total yield = 45.1%). 1H NMR(CDC13, 400 M Hz):5 (ppm)7.22-7.28 (m, 2H), 7.01-7.12 (m, 2 H), 4.68 (s, 2 H), 3.05(s, 3H), 1.65 (q, 2H, J = 7.6 Hz), 1.27(s, 6H), 0.89(t, 3H, J = 7.6 Hz)LC-MS (ESI) [M+H] calad for C14H20FN0, 238.2; found, 238.4.

Reference： [1]Patent: WO2016/101885,2016,A1 .Location in patent: Paragraph 0227; 0228; 0229; 0230; 0231

18
[ 5856-77-9 ]
[ 405-66-3 ]
N-(4-fluorobenzyl)-N,2,2-trimethylbutanamide [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
189 mg	With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 0 - 20℃; for 2h; Inert atmosphere;	[0618] Compound S7: Preparation of N-(4-fluorobenzyl)-N,2,2-trimethylbutanamide [0619] A mixture of K2C03 (207 mg, 1.5 mmol) and methanamine hydrochloride (202 mg, 3.0 mmol) in 5 mL of MeOH was stirred at rt for 30 mm. Then 4-fluorobenzaldehyde (248 mg, 2.0 mmol) was added to the mixture and stirred at rt for 1 h. The mixture was cooled to 0°C, and NaBH4 (113.5 mg, 3.0 mmol) was added in portions. The mixture was stirred at 0°C for lh and warmed to room temperature and stirred for 2h. The solid was filtered and washed with EtOAc. The filtrate was evaporated to dryness and the residue was dissolved in EtOAc and the organic layer was washed with water, brine, dried over Na2SO4. The residue was dissolved in 10 mL of dry THF. DIEA (264 mg, 2.05 mmol) was added, 2,2-dimethylbutanoyl chloride (275 mg, 2.05 mmol) was added slowly to the solution at 0°C under nitrogen, then stirred at room temperature for 2 h. 15 mL of water was added to the solution and extracted with EtOAc (10 mL x 3). The combined organic was washed with 1M HC1, brine, dried with Na2SO4 and concentrated in vacuo. The residue was purified by silica gel column chromatography (PE/EA= 1/2) to give the 189 mg of S7 as a brown solid (total yield = 40%). 1H NMR (400 M Hz, CDC13) 7.21 -7.12 (m, 2H), 6.98-6.93 (m, 2H), 4.54 (s, 2H), 2.95 (s, 3H), 1.64 (q, J= 7.5 Hz, 2H), 1.24 (s, 6H), 0.84(t, J= 7.5 Hz, 3H).LC-MS (ESI) [M+H] calad for: C14H21F2N0, 256.16; found, 256.18.
	With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 0 - 20℃; for 2h; Inert atmosphere;

Reference： [1]Current Patent Assignee: NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING; NAT INST OF BIOLOGICAL SCIENCES BEIJING; NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES - WO2016/101885, 2016, A1 Location in patent: Paragraph 0618; 0619
[2]Ren, Yan; Su, Yaning; Sun, Liming; He, Sudan; Meng, Lingjun; Liao, Daohong; Liu, Xiao; Ma, Yongfen; Liu, Chunyan; Li, Sisi; Ruan, Hanying; Lei, Xiaoguang; Wang, Xiaodong; Zhang, Zhiyuan [Journal of Medicinal Chemistry, 2017, vol. 60, # 3, p. 972 - 986]

19
[ 5856-77-9 ]
[ 89-99-6 ]
N-(2-fluorobenzyl)-2,2-dimethylbutanamide [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
72.6%	With triethylamine; In dichloromethane; at 0 - 20℃; for 10h;	[0184] SOC12 (30m1) was added to the 2, 2-dimethylbutanoic acid (5.22g) in toluene with stirring. Then the reaction mixture was warmed to 80 °C for 5 h. After removal of the solvent, 4.268g of 2,2-dimethylbutanoyl chloride was obtained, which was dissolved in DCM and added dropwise to the (2-fluorophenyl)methanamine (1 .698g) dissolved in DCM contains TEA (4.8g) at 0°C. Stirring was continued at room temperature for 10 h. After all amines had been consumed as judged by TLC, the mixture was quenched with ice-water. Extracted with DCM, dried over Na2SO4, concentrated and purified by silca gel chromatography to give the desired product ( 2.57g, 72.6percent). 1H NMR (CDC13): 7.30-7.34 (m, 1H), 7.23-7.25 (m, 1H), 7.00-7.11 (m, 2H), 6.06 (br, 1H), 4.48 (d, 2H, J= 6.0 Hz), 1.55 (q, 2H, J= 7.6 Hz), 1.16 (s, 6H), 0.81 (t, 3H, J=7.6 Hz).

Reference： [1]Patent: WO2016/101885,2016,A1 .Location in patent: Paragraph 0182; 0183; 0184
[2]Journal of Medicinal Chemistry,2017,vol. 60,p. 972 - 986

20
[ 5856-77-9 ]
[ 41049-53-0 ]
2,2-dimethyl-N-(1-phenylcyclopropyl)butanamide [ No CAS ]