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CAS No. : | 41996-97-8 | MDL No. : | MFCD22493336 |
Formula : | C12H15Br | Boiling Point : | - |
Linear Structure Formula : | - | InChI Key : | UCDGLMPOKKXSDM-UHFFFAOYSA-N |
M.W : | 239.15 | Pubchem ID : | 11118135 |
Synonyms : |
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Signal Word: | Warning | Class: | |
Precautionary Statements: | P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501 | UN#: | |
Hazard Statements: | H315-H319-H335 | Packing Group: | |
GHS Pictogram: |
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
53% | Stage #1: 4-Vinylbenzyl chloride With iodine; magnesium In diethyl ether at 0 - 20℃; for 4.5h; Stage #2: 1,3-dibromo-propane With dilithium tetrachlorocuprate In tetrahydrofuran; diethyl ether at 0 - 20℃; Further stages.; | |
35% | With magnesium In tetrahydrofuran; diethyl ether at 0℃; for 8h; | 1 Synthesis of ω-Halogenoalkylstyrene A total of 100 g of chloromethylstyrene was stirred with metallic magnesium in diethyl ether replaced with nitrogen at 0° C. for 3 hours to yield a magnesium complex. After replacing the solvent with nitrogen-replaced tetrahydrofuran, 1,3-dibromopropane and Li2CuCl4 were added dropwise to the magnesium complex at 0° C., and the reaction was continued at 0° C. for further 5 hours. The obtained products were then fractionated by distillation. In the distillation process, 4-(4-bromobutyl)styrene (hereinafter simply referred to as “4-bromobutylstyrene”) was obtained at 120° C. at a pressure of 0.3 Torr, and the yield on the basis of the material chloromethylstyrene was 35% by mass. The 4-bromobutylstyrene was identified according to an NMR technique described in “Journal of Polymer Science, Polymer Chemistry Edition; vol.20, 1982, pp.3015”. |