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[ CAS No. 194413-58-6 ] {[proInfo.proName]}

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Chemical Structure| 194413-58-6
Chemical Structure| 194413-58-6
Structure of 194413-58-6 * Storage: {[proInfo.prStorage]}
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Product Details of [ 194413-58-6 ]

CAS No. :194413-58-6 MDL No. :MFCD09763655
Formula : C15H14N2O Boiling Point : -
Linear Structure Formula :- InChI Key :WUWDLXZGHZSWQZ-WQLSENKSSA-N
M.W : 238.28 Pubchem ID :5329098
Synonyms :
(Z)-SU5416

Safety of [ 194413-58-6 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P280-P305+P351+P338 UN#:N/A
Hazard Statements:H317-H319 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 194413-58-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 194413-58-6 ]
  • Downstream synthetic route of [ 194413-58-6 ]

[ 194413-58-6 ] Synthesis Path-Upstream   1~5

  • 1
  • [ 2199-58-8 ]
  • [ 59-48-3 ]
  • [ 194413-58-6 ]
YieldReaction ConditionsOperation in experiment
86% With piperidine In methanolReflux General procedure: To a solution of indolin-2-one (compound 1) (200 mg, 1eq.) in MeOH (5 mL), piperidine (1.5 eq.), and correspondingaldehydes (2a–2k) (1.2 eq.) were added. Thereaction mixture was heated to reflux and stirred for 1–4 h,then cooled to room temperature. The mixture was filtered,and the filter cake was washed with MeOH three times, thenthe filter cake was collected and dried under vacuum toremove MeOH to give the desired compounds 3a–3k.
Reference: [1] Journal of Antibiotics, 2018, vol. 71, # 10, p. 887 - 897
[2] Tetrahedron, 2009, vol. 65, # 25, p. 4894 - 4903
[3] ChemMedChem, 2016, vol. 11, # 1, p. 72 - 80
[4] Journal of Medicinal Chemistry, 1998, vol. 41, # 14, p. 2588 - 2603
[5] Synthetic Communications, 2008, vol. 38, # 17, p. 3017 - 3022
  • 2
  • [ 2199-58-8 ]
  • [ 152302-94-8 ]
  • [ 194413-58-6 ]
Reference: [1] Tetrahedron, 2010, vol. 66, # 33, p. 6606 - 6612
  • 3
  • [ 110-89-4 ]
  • [ 2199-58-8 ]
  • [ 59-48-3 ]
  • [ 194413-58-6 ]
Reference: [1] Patent: US5834504, 1998, A,
[2] Patent: US5883116, 1999, A,
[3] Patent: US5883113, 1999, A,
[4] Patent: US6846839, 2005, B1,
  • 4
  • [ 2199-58-8 ]
  • [ 1243657-66-0 ]
  • [ 194413-58-6 ]
Reference: [1] Tetrahedron, 2010, vol. 66, # 33, p. 6606 - 6612
  • 5
  • [ 194413-57-5 ]
  • [ 194413-58-6 ]
Reference: [1] ChemMedChem, 2016, vol. 11, # 1, p. 72 - 80
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