Alternatived Products of [ 189373-41-9 ]
Product Details of [ 189373-41-9 ]
CAS No. : | 189373-41-9 |
MDL No. : | MFCD01321129 |
Formula : |
C10H15N5O3S
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
285.32
|
Pubchem ID : | - |
Synonyms : |
Dbd-ed
|
Safety of [ 189373-41-9 ]
Application In Synthesis of [ 189373-41-9 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 189373-41-9 ]
- 1
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[ 192119-42-9 ]
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[ 107-15-3 ]
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[ 189373-41-9 ]
Yield | Reaction Conditions | Operation in experiment |
92.3% |
In acetonitrile at 60℃; for 6h; |
|
87% |
In acetonitrile at 60℃; for 4h; |
|
|
In acetonitrile at 60℃; for 6h; |
|
Reference:
[1]Liu, Tingting; Jiang, Yan; Liu, Zhenzhen; Li, Jin; Fang, Kun; Zhuang, Chunlin; Du, Lupei; Fang, Hao; Sheng, Chunquan; Li, Minyong
[MedChemComm, 2017, vol. 8, # 8, p. 1668 - 1672]
[2]Uchiyama, Seiichi; Iwai, Kaoru; De Silva, A. Prasanna
[Angewandte Chemie - International Edition, 2008, vol. 47, # 25, p. 4667 - 4669]
[3]Chen, Long; Dong, Gaopan; Han, Guangxi; He, Shipeng; Jiang, Yan; Li, Minyong; Li, Xiang; Liu, Tingting; Qin, Xiaojun; Sheng, Chunquan
[Analytical Chemistry, 2020, vol. 92, # 3, p. 2642 - 2648]
- 2
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[ 189373-41-9 ]
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[ 96-32-2 ]
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[ 1048697-11-5 ]
Yield | Reaction Conditions | Operation in experiment |
45% |
With potassium carbonate In acetonitrile at 70℃; for 6h; |
|
- 3
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[ 189373-41-9 ]
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[ 191108-03-9 ]
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[ 1196721-53-5 ]
Yield | Reaction Conditions | Operation in experiment |
|
With O‐(1H‐benzotriazol‐1‐yl)‐N,N,N′,N′‐tetramethyluronium tetrafluoroborate In acetonitrile at 20℃; |
|
Reference:
[1]Location in patent: scheme or table
Guminski, Yves; Grousseaud, Martial; Cugnasse, Sandrine; Brel, Viviane; Annereau, Jean-Philippe; Vispe, Stephane; Guilbaud, Nicolas; Barret, Jean-Marc; Bailly, Christian; Imbert, Thierry
[Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 9, p. 2474 - 2477]
- 4
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[ 189373-41-9 ]
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[ 24424-99-5 ]
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[ 1334754-81-2 ]
Yield | Reaction Conditions | Operation in experiment |
63% |
Stage #1: 7-((2-aminoethyl)amino)-N, N-dimethylbenzo[c][1, 2, 5]oxadiazole-4-sulfonamide With sodium hydroxide In chloroform; water for 0.25h;
Stage #2: di-<i>tert</i>-butyl dicarbonate at 0 - 20℃; |
|
- 5
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[ 189373-41-9 ]
-
[ 498568-17-5 ]
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7-((2-((1-(3-(1H-imidazol-1-yl)propyl)-4-benzoyl-5-(4-bromophenyl)-2-oxo-2,5-dihydro-1Hpyrrol-3-yl)amino)ethyl) amino)-N,N-dimethylbenzo[c][1,2,5]oxadiazole-4-sulfonamide
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
12.3% |
With acetic acid for 2h; Microwave irradiation; |
|
Reference:
[1]Liu, Tingting; Jiang, Yan; Liu, Zhenzhen; Li, Jin; Fang, Kun; Zhuang, Chunlin; Du, Lupei; Fang, Hao; Sheng, Chunquan; Li, Minyong
[MedChemComm, 2017, vol. 8, # 8, p. 1668 - 1672]
- 6
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[ 7116-16-7 ]
-
[ 189373-41-9 ]
Yield | Reaction Conditions | Operation in experiment |
|
Multi-step reaction with 3 steps
1.1: chlorosulfonic acid / 6 h / 120 - 130 °C
2.1: triethylamine / tetrahydrofuran / 0.5 h / 20 °C
2.2: 1 h / 0 °C
3.1: acetonitrile / 6 h / 60 °C |
|
|
Multi-step reaction with 3 steps
1.1: chlorosulfonic acid / 6 h / 120 - 130 °C
2.1: triethylamine / tetrahydrofuran / 0.5 h / 20 °C
2.2: 1 h / 0 °C
3.1: acetonitrile / 6 h / 60 °C |
|
Reference:
[1]Liu, Tingting; Jiang, Yan; Liu, Zhenzhen; Li, Jin; Fang, Kun; Zhuang, Chunlin; Du, Lupei; Fang, Hao; Sheng, Chunquan; Li, Minyong
[MedChemComm, 2017, vol. 8, # 8, p. 1668 - 1672]
[2]Chen, Long; Dong, Gaopan; Han, Guangxi; He, Shipeng; Jiang, Yan; Li, Minyong; Li, Xiang; Liu, Tingting; Qin, Xiaojun; Sheng, Chunquan
[Analytical Chemistry, 2020, vol. 92, # 3, p. 2642 - 2648]
- 7
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7-chlorobenzo[c][1,2,5]oxadiazole-4-sulfonic acid chloride
[ No CAS ]
-
[ 189373-41-9 ]
Yield | Reaction Conditions | Operation in experiment |
|
Multi-step reaction with 2 steps
1.1: triethylamine / tetrahydrofuran / 0.5 h / 20 °C
1.2: 1 h / 0 °C
2.1: acetonitrile / 6 h / 60 °C |
|
Reference:
[1]Liu, Tingting; Jiang, Yan; Liu, Zhenzhen; Li, Jin; Fang, Kun; Zhuang, Chunlin; Du, Lupei; Fang, Hao; Sheng, Chunquan; Li, Minyong
[MedChemComm, 2017, vol. 8, # 8, p. 1668 - 1672]
Chen, Long; Dong, Gaopan; Han, Guangxi; He, Shipeng; Jiang, Yan; Li, Minyong; Li, Xiang; Liu, Tingting; Qin, Xiaojun; Sheng, Chunquan
[Analytical Chemistry, 2020, vol. 92, # 3, p. 2642 - 2648]
- 8
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[ 189373-41-9 ]
-
C37H75NO16Si8
[ No CAS ]
-
C43H85N5O16SSi8
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
0.8 g |
With triethylamine In tetrahydrofuran for 23h; |
4
In a 20 ml two-necked eggplant flask(N-succinimidyloxycarbonyl) isobutylsilsesquioxane(0.18 mmol) of the compound (2a)4- (N, N-dimethylaminosulfonyl) -7-(2-aminoethylamino) -2, 1, 3-benzoxadiazole, 51.2 mg (0.18 mmol)12 ml of dry THF was added and dissolved. Ten (10) drops of triethylamine were added, and the mixture was stirred for 23 hours.After stirring, the reaction solution was concentrated, dissolved in a mixed solvent of dichloromethane and methanol at 30 ° C., and slowly evaporated to obtain 0.80 g of a yellow-green solid. |
- 9
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[ 189373-41-9 ]
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2-(4-(tert-butyl)-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,5-dihydro-1H-imidazole-1-carbonyl chloride
[ No CAS ]
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C38H41Cl2N7O5S
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
|
With triethylamine In dichloromethane at 20℃; for 0.5h; |
|
Reference:
[1]Chen, Long; Dong, Gaopan; Han, Guangxi; He, Shipeng; Jiang, Yan; Li, Minyong; Li, Xiang; Liu, Tingting; Qin, Xiaojun; Sheng, Chunquan
[Analytical Chemistry, 2020, vol. 92, # 3, p. 2642 - 2648]