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[ CAS No. 18637-83-7 ]

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Chemical Structure| 18637-83-7
Chemical Structure| 18637-83-7
Structure of 18637-83-7 * Storage: {[proInfo.prStorage]}

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Product Details of [ 18637-83-7 ]

CAS No. :18637-83-7 MDL No. :MFCD00043067
Formula : C8H6N4O2 Boiling Point : -
Linear Structure Formula :- InChI Key :N/A
M.W :190.16 g/mol Pubchem ID :-
Synonyms :

Safety of [ 18637-83-7 ]

Signal Word:Danger Class:8
Precautionary Statements:P280-P305+P351+P338-P310 UN#:3259
Hazard Statements:H302-H312-H314 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 18637-83-7 ]

  • Downstream synthetic route of [ 18637-83-7 ]

[ 18637-83-7 ] Synthesis Path-Downstream   1~24

  • 1
  • [ 2745-26-8 ]
  • [ 18637-83-7 ]
  • 2-Furan-2-yl-1-imidazol-1-yl-ethanone [ No CAS ]
  • 3
  • [ 288-32-4 ]
  • [ 16536-30-4 ]
  • [ 51-28-5 ]
  • [ 18637-83-7 ]
YieldReaction ConditionsOperation in experiment
In acetonitrile at 5.8 - 44.7℃; stoped-flow technique; kinetics and mechanism of the nucleophilic substitution reaction; activation energy; spectral study; effect of imidazole concentration of rate constant; effect of triethylamine;
  • 4
  • [ 104-01-8 ]
  • [ 100-39-0 ]
  • [ 71989-26-9 ]
  • [ 102410-65-1 ]
  • [ 18637-83-7 ]
  • (S)-1-[(S)-1-(Benzylamino-methyl)-5-(benzyl-methyl-amino)-pentyl]-4-[2-(4-methoxy-phenyl)-ethyl]-5-phenyl-piperazine-2,3-dione [ No CAS ]
  • 5
  • [ 4919-33-9 ]
  • [ 100-39-0 ]
  • [ 71989-26-9 ]
  • [ 102410-65-1 ]
  • [ 18637-83-7 ]
  • (S)-1-[(S)-1-(Benzylamino-methyl)-5-(benzyl-methyl-amino)-pentyl]-4-[2-(4-ethoxy-phenyl)-ethyl]-5-phenyl-piperazine-2,3-dione [ No CAS ]
  • 6
  • [ 5807-30-7 ]
  • [ 100-39-0 ]
  • [ 71989-26-9 ]
  • [ 102410-65-1 ]
  • [ 18637-83-7 ]
  • (S)-1-[(S)-1-(Benzylamino-methyl)-5-(benzyl-methyl-amino)-pentyl]-4-[2-(3,4-dichloro-phenyl)-ethyl]-5-phenyl-piperazine-2,3-dione [ No CAS ]
  • 7
  • [ 1460-16-8 ]
  • [ 100-39-0 ]
  • [ 71989-26-9 ]
  • [ 102410-65-1 ]
  • [ 18637-83-7 ]
  • (S)-1-[(S)-1-(Benzylamino-methyl)-5-(benzyl-methyl-amino)-pentyl]-4-cycloheptylmethyl-5-phenyl-piperazine-2,3-dione [ No CAS ]
  • 8
  • [ 622-47-9 ]
  • [ 100-39-0 ]
  • [ 71989-26-9 ]
  • [ 102410-65-1 ]
  • [ 18637-83-7 ]
  • (S)-1-[(S)-1-(Benzylamino-methyl)-5-(benzyl-methyl-amino)-pentyl]-5-phenyl-4-(2-p-tolyl-ethyl)-piperazine-2,3-dione [ No CAS ]
  • 9
  • [ 100-39-0 ]
  • [ 71989-26-9 ]
  • [ 102410-65-1 ]
  • [ 18637-83-7 ]
  • [ 4942-47-6 ]
  • (S)-4-(2-Adamantan-1-yl-ethyl)-1-[(S)-1-(benzylamino-methyl)-5-(benzyl-methyl-amino)-pentyl]-5-phenyl-piperazine-2,3-dione [ No CAS ]
  • 10
  • [ 288-32-4 ]
  • [ 1165-91-9 ]
  • [ 18637-83-7 ]
  • 11
  • [ 2620-50-0 ]
  • [ 104-03-0 ]
  • [ 136030-33-6 ]
  • [ 18637-83-7 ]
  • <i>N</i>-benzo[1,3]dioxol-5-ylmethyl-2-[4-(1,3,4-trioxo-1,3,4,6,11,11a-hexahydro-pyrazino[1,2-<i>b</i>]isoquinolin-2-yl)-phenyl]-acetamide [ No CAS ]
  • 12
  • [ 104-03-0 ]
  • [ 78-81-9 ]
  • [ 136030-33-6 ]
  • [ 18637-83-7 ]
  • <i>N</i>-isobutyl-2-[4-(1,3,4-trioxo-1,3,4,6,11,11a-hexahydro-pyrazino[1,2-<i>b</i>]isoquinolin-2-yl)-phenyl]-acetamide [ No CAS ]
  • 13
  • [ 104-03-0 ]
  • [ 2516-34-9 ]
  • [ 136030-33-6 ]
  • [ 18637-83-7 ]
  • <i>N</i>-cyclobutyl-2-[4-(1,3,4-trioxo-1,3,4,6,11,11a-hexahydro-pyrazino[1,2-<i>b</i>]isoquinolin-2-yl)-phenyl]-acetamide [ No CAS ]
  • 14
  • [ 104-03-0 ]
  • [ 118-31-0 ]
  • [ 101555-63-9 ]
  • [ 18637-83-7 ]
  • <i>N</i>-naphthalen-1-ylmethyl-2-[4-(1,3,4-trioxo-octahydro-pyrido[1,2-<i>a</i>]pyrazin-2-yl)-phenyl]-acetamide [ No CAS ]
  • 15
  • [ 104-03-0 ]
  • [ 118-31-0 ]
  • [ 77128-73-5 ]
  • [ 18637-83-7 ]
  • 2-[4-(3-benzyl-4-methyl-2,5,6-trioxo-piperazin-1-yl)-phenyl]-<i>N</i>-naphthalen-1-ylmethyl-acetamide [ No CAS ]
  • 16
  • [ 104-03-0 ]
  • [ 118-31-0 ]
  • [ 136030-33-6 ]
  • [ 18637-83-7 ]
  • <i>N</i>-naphthalen-1-ylmethyl-2-[4-(1,3,4-trioxo-1,3,4,6,11,11a-hexahydro-pyrazino[1,2-<i>b</i>]isoquinolin-2-yl)-phenyl]-acetamide [ No CAS ]
  • 17
  • [ 104-03-0 ]
  • [ 118-31-0 ]
  • [ 102410-65-1 ]
  • [ 18637-83-7 ]
  • <i>N</i>-naphthalen-1-ylmethyl-2-[4-(2,3,6-trioxo-5-phenyl-piperazin-1-yl)-phenyl]-acetamide [ No CAS ]
  • 18
  • [ 104-03-0 ]
  • [ 118-31-0 ]
  • [ 103478-58-6 ]
  • [ 18637-83-7 ]
  • 2-[4-(3-isopropyl-4-methyl-2,5,6-trioxo-piperazin-1-yl)-phenyl]-<i>N</i>-naphthalen-1-ylmethyl-acetamide [ No CAS ]
  • 19
  • [ 3740-52-1 ]
  • [ 118-31-0 ]
  • [ 136030-33-6 ]
  • [ 18637-83-7 ]
  • <i>N</i>-naphthalen-1-ylmethyl-2-[2-(1,3,4-trioxo-1,3,4,6,11,11a-hexahydro-pyrazino[1,2-<i>b</i>]isoquinolin-2-yl)-phenyl]-acetamide [ No CAS ]
  • 20
  • [ 1877-73-2 ]
  • [ 118-31-0 ]
  • [ 136030-33-6 ]
  • [ 18637-83-7 ]
  • <i>N</i>-naphthalen-1-ylmethyl-2-[3-(1,3,4-trioxo-1,3,4,6,11,11a-hexahydro-pyrazino[1,2-<i>b</i>]isoquinolin-2-yl)-phenyl]-acetamide [ No CAS ]
  • 21
  • [ 5600-62-4 ]
  • [ 118-31-0 ]
  • [ 136030-33-6 ]
  • [ 18637-83-7 ]
  • <i>N</i>-naphthalen-1-ylmethyl-4-[4-(1,3,4-trioxo-1,3,4,6,11,11a-hexahydro-pyrazino[1,2-<i>b</i>]isoquinolin-2-yl)-phenyl]-butyramide [ No CAS ]
  • 22
  • [ 104-03-0 ]
  • [ 136030-33-6 ]
  • [ 18637-83-7 ]
  • [ 107-11-9 ]
  • <i>N</i>-allyl-2-[4-(1,3,4-trioxo-1,3,4,6,11,11a-hexahydro-pyrazino[1,2-<i>b</i>]isoquinolin-2-yl)-phenyl]-acetamide [ No CAS ]
  • 23
  • [ 104-03-0 ]
  • [ 136030-33-6 ]
  • [ 18637-83-7 ]
  • [ 3218-02-8 ]
  • <i>N</i>-cyclohexylmethyl-2-[4-(1,3,4-trioxo-1,3,4,6,11,11a-hexahydro-pyrazino[1,2-<i>b</i>]isoquinolin-2-yl)-phenyl]-acetamide [ No CAS ]
  • 24
  • [ 59649-56-8 ]
  • [ 18637-83-7 ]
  • [ 862270-94-8 ]
YieldReaction ConditionsOperation in experiment
In tetrahydrofuran; for 0.5h;Reflux; Example 1 : 5-hydroxy-1,4-dihydroquinoxaline-2,3-dione A solution of <strong>[59649-56-8]2,3-diaminophenol</strong> (50 g) and 1 ,1'-oxalyldiimidazole (92 g) and tetrahydrofurane (1.2 L) is refluxed 30 minutes. The solvent is removed under reduced pressure and the remaining solid taken into ethyl acetate. The organic phase is washed with 1 M aqueous hydrochloric solution, dried over sodium sulphate and concentrated under vacuum. The crude solid obtained is recrystallised from dimethylformamide; yield: 14.8 g; MS: 177.1 (M-1);1H NMR (DMSO-de, 300 MHz): delta [ppm] 6.61 (m, 2H); 6.91 (ss, 1 H), 10.21 (s(1 H); 11.05 (s, 1 H); 11.85 (s, 1 H).
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