Home Cart 0 Sign in  

[ CAS No. 14024-85-2 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 14024-85-2
Chemical Structure| 14024-85-2
Structure of 14024-85-2 * Storage: {[proInfo.prStorage]}
Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Quality Control of [ 14024-85-2 ]

Related Doc. of [ 14024-85-2 ]

Alternatived Products of [ 14024-85-2 ]

Product Details of [ 14024-85-2 ]

CAS No. :14024-85-2 MDL No. :MFCD32856734
Formula : C10H10Br2N2Ni Boiling Point : -
Linear Structure Formula :- InChI Key :-
M.W : 376.70 Pubchem ID :-
Synonyms :

Calculated chemistry of [ 14024-85-2 ]

Physicochemical Properties

Num. heavy atoms : 15
Num. arom. heavy atoms : 12
Fraction Csp3 : 0.0
Num. rotatable bonds : 2
Num. H-bond acceptors : 0.0
Num. H-bond donors : 0.0
Molar Refractivity : 66.33
TPSA : 9.86 Ų

Pharmacokinetics

GI absorption : Low
BBB permeant : No
P-gp substrate : Yes
CYP1A2 inhibitor : No
CYP2C19 inhibitor : Yes
CYP2C9 inhibitor : No
CYP2D6 inhibitor : No
CYP3A4 inhibitor : No
Log Kp (skin permeation) : -5.7 cm/s

Lipophilicity

Log Po/w (iLOGP) : 0.0
Log Po/w (XLOGP3) : 4.08
Log Po/w (WLOGP) : -3.83
Log Po/w (MLOGP) : 1.76
Log Po/w (SILICOS-IT) : 1.33
Consensus Log Po/w : 0.67

Druglikeness

Lipinski : 0.0
Ghose : None
Veber : 0.0
Egan : 0.0
Muegge : 0.0
Bioavailability Score : 0.55

Water Solubility

Log S (ESOL) : -5.21
Solubility : 0.00234 mg/ml ; 0.00000622 mol/l
Class : Moderately soluble
Log S (Ali) : -3.99
Solubility : 0.0384 mg/ml ; 0.000102 mol/l
Class : Soluble
Log S (SILICOS-IT) : -3.18
Solubility : 0.251 mg/ml ; 0.000667 mol/l
Class : Soluble

Medicinal Chemistry

PAINS : 0.0 alert
Brenk : 0.0 alert
Leadlikeness : 2.0
Synthetic accessibility : 2.3

Safety of [ 14024-85-2 ]

Signal Word:Danger Class:9
Precautionary Statements:P501-P273-P260-P270-P264-P280-P391-P314-P337+P313-P305+P351+P338-P301+P312+P330 UN#:3077
Hazard Statements:H302-H319-H372-H410 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 14024-85-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 14024-85-2 ]
  • Downstream synthetic route of [ 14024-85-2 ]

[ 14024-85-2 ] Synthesis Path-Upstream   1~1

  • 1
  • [ 14024-85-2 ]
  • [ 542-52-9 ]
  • [ 2050-60-4 ]
  • [ 13463-39-3 ]
Reference: [1] Journal of Organometallic Chemistry, 1983, vol. 254, # 2, p. 267 - 272
Same Skeleton Products
Historical Records

Similar Product of
[ 14024-85-2 ]

Chemical Structure| 2640505-89-9

A1461982[ 2640505-89-9 ]

Dibromobis(t-Bu pyridine)nickel

Reason: Derivatives