Alternatived Products of [ 109581-83-1 ]
Product Details of [ 109581-83-1 ]
CAS No. : | 109581-83-1 |
MDL No. : | |
Formula : |
C14H20ClNO9
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
381.76
|
Pubchem ID : | - |
Synonyms : |
|
Safety of [ 109581-83-1 ]
Signal Word: | |
Class: | |
Precautionary Statements: | |
UN#: | |
Hazard Statements: | |
Packing Group: | |
Application In Synthesis of [ 109581-83-1 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 109581-83-1 ]
- 1
-
[ 109581-83-1 ]
-
[ 107-18-6 ]
-
[ 116288-59-6 ]
-
[ 116347-85-4 ]
-
(2R,3R,4R,5R,6R)-5-acetamido-2-(acetoxymethyl)-6-(allyloxy)tetrahydro-2H-pyran-3,4-diyl diacetate
[ No CAS ]
-
[ 10385-50-9 ]
Yield | Reaction Conditions | Operation in experiment |
1: 2.59 g
2: 0.84 g
3: 0.3 g
4: 0.38 g |
With 4 A molecular sieve; mercury(II) cyanide In nitromethane; toluene 1.) 15 min, r.t.,; |
|
- 2
-
[ 3006-60-8 ]
-
[ 109581-83-1 ]
Yield | Reaction Conditions | Operation in experiment |
45% |
With titanium(IV) tetrachloride In dichloromethane at 0 - 50℃; Inert atmosphere; |
5.5-64.1 Step 1:
To a mixture of (2S,3R,4R,5R,6R)-3-acetamido-6-(acetoxymethyl)tetrahydro-2H- pyran-2,4,5-triyl triacetate (A92-1, 20.0 g, 51.4 mmol) in DCM (200 mL) was added TiCh (61.6 mL,1 M in DCM) at 0°C under N2. After refluxing at 50°C overnight, the mixture was concentrated and purified by chromatography (0-80% ethyl acetate in petroleum) to give (2R,3R,4R,5R)-5-acetamido-2-(acetoxymethyl)-6-chlorotetrahydro-2H-pyran-3,4-diyl diacetate (A92-2, 8.5 g, 45% yield) as white solid. LC-MS (ESI) found: 366 [M+l]+. |
45% |
With titanium(IV) tetrachloride In dichloromethane at 0 - 50℃; Inert atmosphere; |
5.5-64.1 Step 1:
To a mixture of (2S,3R,4R,5R,6R)-3-acetamido-6-(acetoxymethyl)tetrahydro-2H- pyran-2,4,5-triyl triacetate (A92-1, 20.0 g, 51.4 mmol) in DCM (200 mL) was added TiCh (61.6 mL,1 M in DCM) at 0°C under N2. After refluxing at 50°C overnight, the mixture was concentrated and purified by chromatography (0-80% ethyl acetate in petroleum) to give (2R,3R,4R,5R)-5-acetamido-2-(acetoxymethyl)-6-chlorotetrahydro-2H-pyran-3,4-diyl diacetate (A92-2, 8.5 g, 45% yield) as white solid. LC-MS (ESI) found: 366 [M+l]+. |