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[ CAS No. 100823-03-8 ] {[proInfo.proName]}

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Cat. No.: {[proInfo.prAm]}
Chemical Structure| 100823-03-8
Chemical Structure| 100823-03-8
Structure of 100823-03-8 * Storage: {[proInfo.prStorage]}
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Product Details of [ 100823-03-8 ]

CAS No. :100823-03-8 MDL No. :MFCD03085319
Formula : C20H22N2O2 Boiling Point : -
Linear Structure Formula :- InChI Key :NRPIRIUWEKTNGQ-UHFFFAOYSA-N
M.W : 322.40 Pubchem ID :1235479
Synonyms :

Safety of [ 100823-03-8 ]

Signal Word:Warning Class:
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501 UN#:
Hazard Statements:H302-H315-H319-H335 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 100823-03-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 100823-03-8 ]

[ 100823-03-8 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 75-36-5 ]
  • [ 100823-03-8 ]
  • [ 100823-05-0 ]
YieldReaction ConditionsOperation in experiment
With triethylamine In tetrahydrofuran at 20℃; for 1h;
  • 2
  • [ 100823-00-5 ]
  • [ 100823-03-8 ]
YieldReaction ConditionsOperation in experiment
With hydrogen In acetone for 2h; Heating;
With hydrogen In acetone for 2h; Heating / reflux; In another aspect of the present disclosure, a thalidomide analog is synthesized by substituting the glutaramide ring with an aromatic group. In one embodiment, Compound 4 is synthesized by using the reactants 5-nitrophthalic anhydrides and 2,6-diisopropylaniline to produce (2,6-diisopropylphenyl)-5-amino-1H-isoindole-1,3-dione, which is further processed to form Compound 4. In a preferred embodiment, 5nitrophthalic anhydrides and 2,6-diisopropylaniline is refluxed with AcOH for 5 hrs to produce (2,6-diisopropylphenyl)-5-amino-1H-isoindole-1,3-dione. (2,6-diisopropylphenyl)-5-amino-1H-isoindole-1,3-dione is further refluxed with H2, Pd/C, and acetone for 2 hrs to form Compound 4.
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