Life Science / Inhibitors/Agonists / Cell Cycle / Chk

Cat. No. Name/Description Purity
A165759 AZD-7762

98+%
A853008 Prexasertib

98%
A1177301 Prexasertib Mesylate Hydrate

98%
A141550 Rabusertib

98%
A200833 SCH900776

98+%
A690852 GDC-0575

98+%
A144417 BML-277

98%
A191306 Prexasertib 2HCl

98%
A433196 CCT245737

97+%
A465968 SB-218078

98%
A119534 Chk2-IN-1

95+%
A1365457 Chk1-IN-5

98%
A1176700 CHK1-IN-2

99+%
A1361702 Prexasertib dimesylate

98%
A869154 SCH900776 (S-isomer)

98+%
A1483415 PV1115

98%
A415147 MU380

99+%
A525147 PV-1019

95%
A359994 GDC-0425

99+%
A1177764 CHK-IN-1

No Data

Name/Description Chk1 Chk2 Other Targets Purity
Rabusertib ++

Chk1, IC50: 7 nM

99%+
PF-477736 ++++

Chk1, Ki: 0.49 nM

98%
CHIR-124 ++++

Chk1, IC50: 0.3 nM

PDGFR,GSK-3,FLT3 98+%
SCH900776 +++

Chk1, IC50: 3 nM

99%+
SAR-020106 +

Chk1, IC50: 13.3 nM

98%
CCT245737 +++

Chk1, IC50: 1.4 nM

97+%
Prexasertib 2HCl ++++

Chk1, Ki: 0.9 nM

++

Chk2, IC50: 8 nM

RSK 99%+
BML-277 +

Chk2, IC50: 15 nM

99%+
AZD-7762 +++

Chk1, IC50: 5 nM

++

Chk2, IC50: <10 nM

99%+
1. Hovering the mouse over the "+" can display the specific value of the relevant IC50. The more "+", the stronger the inhibitory effect. 2. "✔" Indicates that the compound has inhibitory effects on the corresponding subtypes, but there is currently no relevant data on the intensity of inhibition.