Alternatived Products of [ 7120-03-8 ]
Product Details of [ 7120-03-8 ]
CAS No. : | 7120-03-8 |
MDL No. : | MFCD06739726 |
Formula : |
C10H9BrN4S
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
297.17
|
Pubchem ID : | - |
Synonyms : |
|
Safety of [ 7120-03-8 ]
Signal Word: | |
Class: | |
Precautionary Statements: | |
UN#: | |
Hazard Statements: | |
Packing Group: | |
Application In Synthesis of [ 7120-03-8 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 7120-03-8 ]
- 1
-
[ 2114-02-5 ]
-
[ 99-90-1 ]
-
[ 7120-03-8 ]
Yield | Reaction Conditions | Operation in experiment |
93% |
With Oxone; sodium bromide In methanol at 60℃; for 2h; |
7 Example 7: Synthesis of N-(4-(4-bromophenyl)-1,3-thiazol-2-yl)guanidine (Formula 14)
Add 4-bromoacetophenone (0.80 g, 4.0 mmol)Dissolved in MeOH (40 mL),Add Oxone (2.70 g, 4.4 mmol) sequentiallyAnd NaBr (0.45 g, 4.4 mmol),Amidinothiourea (0.47 g, 4.0 mmol) was addedInto the mixture slowly warm up to 60°C,The reaction is completed after refluxing for 2h,The reaction mixture is filtered,The filtrate was taken and concentrated in vacuo.Dissolve the crude product in water,Adjust the pH to 8-9 with ammonia water,There is solid precipitation,Suction filtration, take the filter cake, and dry.Finally, the crude product obtained is recrystallized with MeOH,The product N-(4-(4-bromophenyl)-1,3-thiazol-2-yl)guanidine (1.10 g) was obtained with the following structure,The yield was 93%. |