630-580-1088 sales@ambeed.com
Structure Search

List Search MOL Search Structure Search

0
Chemistry
Asymmetric Synthesis >>Chiral Building BlocksChiral Catalysts, Chiral Ligands and Chiral ReagentsChiral Resolution ReagentsBoronic acids/esters >>Aliphatic BoronsAromatic BoronsOther BoronsOxaborolesCatalysis Chemistry >>Achiral Crown LigandsC-H ActivationCarbon-Donor LigandsChiral Carbon LigandsChiral Crown LigandsChiral Olefin LigandsCross-CouplingCross-Coupling Using Transition Metal CatalystsDACH or Trost LigandsChemical Biology >>Conjugation Chemistry
GlycoscienceLinkers and CrosslinkersNucleic Acid ChemistryPEGylationPeptide ChemistryPhotolabile Protecting GroupHeterocyclic Building Blocks >>AcridinesAliphatic HeterocyclesAromatic HeterocyclesAzetidinesBenzimidazolesBenzisoxazolesBenzodioxansBenzofuransBenzothiazolesInorganic reagents >>Inorganic ReagentOrganic Building Blocks >>Acid AnhydridesAcyl Chlorides
AlcoholsAldehydesAliphatic Chain HydrocarbonsAliphatic Cyclic HydrocarbonsAlkenesAlkylsAlkynesOrganometallic Reagents >>Grignard ReagentsOrganoarsenicOrganobismuthOrganoboronOrganogermaniumOrganolithiumOrganomercuryOrganosiliconOrganotinSpecialty Synthesis >>Enzyme-Mediated SynthesisFluorous SynthesisIonic Liquids
Solid Supported SynthesisStains and Dyes >>Acid DyesAzoic DyesBasic DyesDirect DyesDisperse DyesDye IntermediatesMordant DyesOil DyesOther Stains and DyesSynthetic Reagents >>Acids and BasesC-C Bond FormationC-X Bond Formation (Halogen)C-X Bond Formation (Non-Halogen)Chelation and Complexation CompoundsCondensation AgentsCouplingDehydrating ReagentsFluorination Reagent
Pharmaceutical Intermediates
Analgesics >>BenzhydrocodoneBicifadineCapsaicinCelecoxibDebio-0827DexamethasoneElagolix SodiumEsketamine HydrochlorideIbuprofen SodiumAnesthetics >>CiprofolEsketamine HydrochlorideFospropofol Fospropofol DisodiumLevobupivacaine RemimazolamRemimazolam BesilateRemimazolam BesylateRopivacaineAnti-Addiction Agents >>Kakonein
Lofexidine HydrochlorideVarenicline Anti-inflammatory Agents >>ApremilastAsunaprevirATB-346 RelatedBalsalazide BaricitinibBencycloquidium BromideBudesonideCefiderocol Sulfate TosylateCeftaroline Fosamil AcetateAntibacterials >>AFN-1252 RelatedAlatrofloxacin Bedaquiline FumarateBesifloxacin BrilacidinCaspofungin AcetateCefiderocol Sulfate TosylateCefilavancinCeftaroline Fosamil
Anticonvulsants >>BrivaracetamCannabidiolEscitalopram OxalateEslicarbazepine Acetate RelatedFosphenytoinGabapentin EnacarbilJNJ-10234094LacosamideLevetiracetam RelatedAntidementia Agents >>Azeliragon RelatedDavunetideDonepezil HydrochlorideDonepezil RelatedEnsaculinFlorbetaben Flortaucipir F 18Flutemetamol IdalopirdineAntidepressants >>4-Chlorokynurenine
AgomelatineAgomelatine RelatedAllopregnanolone RelatedAmibegronAmitifadineAripiprazole RelatedBasimglurantBefloxatoneAntiemetics >>AprepitantAprepitant RelatedDolasetron RelatedDolasetron Mesylate HydrateFosaprepitant DimeglumineFosaprepitant RelatedOlanzapinePalonosetron RelatedPalonosetron HydrochlorideAntifungals >>Anidulafungin RelatedCabotegravirMore >>
Inhibitors/Agonists
ADC >>ADC AntibodyADC LinkerADC Linker with PayloadADC ToxinAntibody-Drug Conjugates (ADCs)Drug-Linker Conjugates for ADCAngiogenesis >>ALKBcr-AblBTKEGFRFAKFGFRFLT3HER2HIFAnti-infection >>3CLproAntibacterialAntibioticAntifungal
AntiparasiticAntiprotozoalAntiviralArenavirusBVDVApoptosis >>Apoptosis InducerBcl-2Bcl-6BRKc-Mycc-RETC/EBPCARDCaspaseAutophagy >>Atg4ATG4BATTECsAUTACsAutophagyBeclin1
FKBPLC3LRRK2Biochemical Reagent >>Cell Cycle >>AntifolateAPCAurora KinaseBUBCasein KinaseCdc25CDKChkCRISPR/Cas9Cytoskeleton >>ActinArp2/3 ComplexCYTHCytoplasmic DyneinDynaminFAKMore >>
Material Science
Aggregation-Induced Emission >>Other AIE BlocksTetraphenylethylene SeriesCOFs Linkers >>Aldehyde COFs LinkersAlkynyl COFs LinkersAmine COFs LinkersBoric COFs LinkersCyano COFs LinkersMultifunctional COFs linkersOther COFs linkersTriptycene SeriesElectronic Materials >>Battery MaterialsDye-Sensitized Solar Cell (DSSC) MaterialsElectronic MaterialLiquid Crystal (LC) MaterialsMolecular ConductorsOrganic Light-Emitting Diode (OLED) MaterialsOrganic Solar Cell (OPV) MaterialsOrganic Transistor (OFET) MaterialsPerovskite Solar Cell (PSC) MaterialsMagnetic Materials >>Magnetic Ionic LiquidsMagnetic MaterialMagnetic Metal Complexes
Organic Radicals Material Chemical Compounds >>Ligands for Functional Metal ComplexesLiquid Crystal (LC) Building BlocksPhthalocyanine Building BlocksPolymer and Macromolecule Semiconductor Building BlocksSmall Molecule Semiconductor Building BlocksSolubility Enhancing Reagents Supramolecular Host Materials MOF Ligands >>Carboxylic Acid MOF LigandsCarboxylic Acid Nitrogen-Containing Mixed MOF LigandsNitrogen-Containing MOF LigandsOther MOF LigandsNanomaterials >>Carbon NanomaterialsCeramic MembranesDendrimersGold NanoparticlesIron Oxide NanoparticlesMaterials by ApplicationMesoporous MaterialsMetals and Metal AlloysNano Minerals: NanoclaysOLED Materials >>Dopant
HostHTMOLED IntermediatesOther OLED related materialsOptical Materials >>Coumarin DyesCyanine and Squarylium DyesDCM DyesDipyrromethene DyesFluorescence MaterialsFluorescent ProbesHeat and Pressure Sensitive DyesNear-Infrared (NIR) DyesOrganic Non-Linear Optical (NLO) MaterialsOrganic Pigments >>Organic PigmentOther Materials >>Mateial OtherPolymer Science >>MonomersPolymer AdditivesPolymerization ReagentsPolymersResins
Contact Us
Home Cart 0 Sign in  
Chemistry
Heterocyclic Building Blocks
Benzofurans
4-Methylbenzofuran
Chemistry
Heterocyclic Building Blocks
Benzofurans

[ CAS No. 5670-23-5 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 5670-23-5
Chemical Structure| 5670-23-5
Structure of 5670-23-5 * Storage: {[proInfo.prStorage]}
Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

For Research Only 110K+ Compounds Competitive Price 1-2 Day Shipping

Quality Control of [ 5670-23-5 ]

COA NMR CNMR HPLC LC-MS

Related Doc. of [ 5670-23-5 ]

SDS Specification
Alternatived Products of [ 5670-23-5 ]

Product Details of [ 5670-23-5 ]

CAS No. :5670-23-5 MDL No. :MFCD18450776
Formula : C9H8O Boiling Point : -
Linear Structure Formula :- InChI Key :-
M.W : 132.16 Pubchem ID :-
Synonyms :

Safety of [ 5670-23-5 ]

Signal Word: Class:
Precautionary Statements: UN#:
Hazard Statements: Packing Group:

Application In Synthesis of [ 5670-23-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 5670-23-5 ]

[ 5670-23-5 ] Synthesis Path-Downstream   1~4

  • 1
  • [ 18362-36-2 ]
  • [ 5670-23-5 ]
Reference： [1]Bollettino Scientifico della Facolta di Chimica Industriale di Bologna,1952,vol. 10,p. 168
  • 2
  • [ 14847-51-9 ]
  • [ 5670-23-5 ]
Reference： [1]Patent: WO2016/201168,2016,A1
  • 3
  • [ 799766-13-5 ]
  • [ 5670-23-5 ]
YieldReaction ConditionsOperation in experiment
75% To a solution of <strong>[799766-13-5]7-bromo-4-methylbenzofuran</strong> (9.61 g) in THF (228 mL) at -78 °C was slowly added 2.5 M nBuLi in hexanes (21.9 mL, 54.6 mmol, 1.2 equiv). The resultant reaction mixture was stirred for 1 h, then quenched by the addition of water. The mixture was allowed to warm to RT extracted with EtOAc. The organic extracts were dried over Na2SO4 and evaporated. The oily residue was heated at 80 °C in the presence of CaH2, then distilled under vacuum at 110 °C to afford the product as a clear oil(4.51 g, 75percent). ?H NMR (500 MHz, CDC13) (57.64 (d, I = 2.2 Hz, 1H), 7.40 (d, I = 7.8 Hz, 1H), 7.22 (dd, I = 8.2, 7.3 Hz, 1H), 7.06 (m, 1H), 6.81 (d, I = 2.2 Hz, 1H), 2.54 (s, 3H).
Reference： [1]Patent: WO2016/201168,2016,A1 .Location in patent: Paragraph 0252
  • 4
  • [ 110-00-9 ]
  • [ 534-22-5 ]
  • [ 271-89-6 ]
  • [ 17059-52-8 ]
  • [ 5670-23-5 ]
  • [ 59020-74-5 ]
  • [ 4265-25-2 ]
YieldReaction ConditionsOperation in experiment
2.8%; 1.9%; 2.7% With aluminum (III) chloride; acetic acid; In water; at 140℃; for 3h; Preparing an aqueous acetic acid solution having a volume ratio of acetic acid to water of 3:1,2 mL of this aqueous acetic acid solution was added to a 10 ml reaction tube, and 0.01 g of furan, 0.01 g of 2-methylfuran and 0.1 g of an aluminum chloride catalyst were added to the reaction tube.The reaction tube was reacted at 140 C for 3 hours, and the reaction product was dissolved in dichloromethane.The product was analyzed by GC/MS (see Figure 5), and the product contained 2-methylbenzofuran.4-methylbenzofuran and 7-methylbenzofuran,There are also benzofuran (obtained from furan itself) and 2,7-dimethylbenzofuran (obtained by self-reaction of 2-methylbenzofuran). Quantitative analysis using GC-FID,The yield of 2-methylbenzofuran was 2.7%, and the yield of 4-methylbenzofuran was 1.9%.The yield of 7-methylbenzofuran was 2.8%.The aqueous acetic acid solution and the main product can be separated and recovered by distillation.
Reference： [1]Patent: CN109503531,2019,A .Location in patent: Paragraph 0106-0109

Tags: 5670-23-5 synthesis path| 5670-23-5 SDS| 5670-23-5 COA| 5670-23-5 purity| 5670-23-5 application| 5670-23-5 NMR| 5670-23-5 COA| 5670-23-5 structure

Same Skeleton Products
Related Products
Categories
Chemistry
Heterocyclic Building Blocks
Benzofurans
Historical Records