Home Cart 0 Sign in  

[ CAS No. 169624-67-3 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 169624-67-3
Chemical Structure| 169624-67-3
Structure of 169624-67-3 * Storage: {[proInfo.prStorage]}
Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Quality Control of [ 169624-67-3 ]

Related Doc. of [ 169624-67-3 ]

Alternatived Products of [ 169624-67-3 ]

Product Details of [ 169624-67-3 ]

CAS No. :169624-67-3 MDL No. :MFCD01318734
Formula : C26H24N2O5 Boiling Point : -
Linear Structure Formula :- InChI Key :WJQWIPAQNBOEBX-QHCPKHFHSA-N
M.W : 444.48 Pubchem ID :11328236
Synonyms :

Safety of [ 169624-67-3 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 169624-67-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 169624-67-3 ]
  • Downstream synthetic route of [ 169624-67-3 ]

[ 169624-67-3 ] Synthesis Path-Upstream   1~7

  • 1
  • [ 35661-40-6 ]
  • [ 169624-67-3 ]
YieldReaction ConditionsOperation in experiment
16.2 mg
Stage #1: With piperidine In N,N-dimethyl-formamide at 20℃; for 0.833333 h;
Stage #2: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane; N,N-dimethyl-formamide at 20℃; for 16 h;
Stage #3: With trifluoroacetic acid In dichloromethane; N,N-dimethyl-formamide for 1 h;
General procedure: The Fmoc-amino acid-Wang resin (300 mg) was suspended in a 30percent piperidine solution in DMF and stirred 50 min at r.t (room temperature).The resin was washed with CH2Cl2 (3×2 mL), EtOAc(3×2 mL), MeOH (3×2 mL) and CH2Cl2 (2 mL), and finally dried in vacuum. The resin was suspended in 5 mL of a DMF:DCM (2:1) mixture and Fmoc-amino acid (3 equiv.), 1-hydroxybenzotriazole (3 equiv.), 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (3 equiv.) and diisopropylethylamine(3 equiv.) were successively added. The solution was stirred at r.t. for 16 h. After this, the resin was washed with DMF(3×2 mL), CH2Cl2 (3×2 mL), MeOH (3×2 mL) and CH2Cl2 (2 mL), and finally dried in vacuum. Resin was treated with 5 mL of 10percent TFA in CH2Cl2 for 1 h. The mixture was filtered and the filtrate was evaporated under reduced pressure to give the crude product.
Reference: [1] Bioorganic Chemistry, 2018, vol. 81, p. 211 - 221
  • 2
  • [ 7364-42-3 ]
  • [ 35661-40-6 ]
  • [ 169624-67-3 ]
Reference: [1] Journal of Organic Chemistry, 2012, vol. 77, # 6, p. 2689 - 2702
  • 3
  • [ 86060-92-6 ]
  • [ 56-40-6 ]
  • [ 169624-67-3 ]
Reference: [1] Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2005, vol. 44, # 11, p. 2328 - 2332
  • 4
  • [ 1316293-48-7 ]
  • [ 169624-67-3 ]
Reference: [1] Rapid Communications in Mass Spectrometry, 2011, vol. 25, # 14, p. 1949 - 1958
  • 5
  • [ 35661-40-6 ]
  • [ 169624-67-3 ]
Reference: [1] Rapid Communications in Mass Spectrometry, 2011, vol. 25, # 14, p. 1949 - 1958
  • 6
  • [ 103321-57-9 ]
  • [ 169624-67-3 ]
Reference: [1] Rapid Communications in Mass Spectrometry, 2011, vol. 25, # 14, p. 1949 - 1958
  • 7
  • [ 721-90-4 ]
  • [ 82911-69-1 ]
  • [ 169624-67-3 ]
Reference: [1] Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1995, # 4, p. 723 - 730
Same Skeleton Products
Historical Records

Related Functional Groups of
[ 169624-67-3 ]

Amino Acid

Chemical Structure| 108321-39-7

[ 108321-39-7 ]

Fmoc-D-Asparagine

Similarity: 0.87

Chemical Structure| 13122-90-2

[ 13122-90-2 ]

Boc-Phe-Phe-OH

Similarity: 0.86

Chemical Structure| 35661-60-0

[ 35661-60-0 ]

Fmoc-Leu-OH

Similarity: 0.84

Chemical Structure| 114360-54-2

[ 114360-54-2 ]

Fmoc-D-Leu-OH

Similarity: 0.84

Chemical Structure| 117322-30-2

[ 117322-30-2 ]

Fmoc-cycloleucine

Similarity: 0.83