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[ CAS No. 1319720-64-3 ] {[proInfo.proName]}

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Cat. No.: {[proInfo.prAm]}
Chemical Structure| 1319720-64-3
Chemical Structure| 1319720-64-3
Structure of 1319720-64-3 * Storage: {[proInfo.prStorage]}
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Product Details of [ 1319720-64-3 ]

CAS No. :1319720-64-3 MDL No. :MFCD27980034
Formula : C21H18BrN Boiling Point : -
Linear Structure Formula :- InChI Key :-
M.W : 364.28 Pubchem ID :-
Synonyms :

Safety of [ 1319720-64-3 ]

Signal Word:Warning Class:
Precautionary Statements:P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 UN#:
Hazard Statements:H315-H319 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 1319720-64-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1319720-64-3 ]

[ 1319720-64-3 ] Synthesis Path-Downstream   1~5

  • 3
  • [ 1319720-64-3 ]
  • [ 531-91-9 ]
  • C66H54N4 [ No CAS ]
YieldReaction ConditionsOperation in experiment
With tri-tert-butyl phosphine; potassium tert-butylate; palladium diacetate; In 5,5-dimethyl-1,3-cyclohexadiene; at 120℃; for 24h;Inert atmosphere; A 1 L three-necked flask was charged with Compound1-4, benzidine, potassium tert-butoxide,Tri-tert-butylphosphine, xylene was added, and under nitrogen protectionHeated to 120 DEG C for 24 hours, cooled to 100 DEG C,After filtration, the filtrate was concentrated under reduced pressureAnd column chromatography was used to obtain Compound 2.
With tri-tert-butyl phosphine; potassium tert-butylate; In 5,5-dimethyl-1,3-cyclohexadiene; at 120℃; for 24h;Inert atmosphere; In 1L of three compound is added in the flask 1 - 4 and biphenyl diamine, tertiary butyl alcohol potassium, tri-butyl phosphate, xylene, under the protection of nitrogen, heated to 120 degrees 24 hours, cooled to 100 degrees, filtration, filtrate under reduced pressure to remove the solvent, then over the column for column chromatography separation to obtain compound 2
  • 4
  • [ 1319720-64-3 ]
  • [ 955959-89-4 ]
  • [ 2286381-57-3 ]
YieldReaction ConditionsOperation in experiment
With tri-tert-butyl phosphine; palladium diacetate; sodium t-butanolate In toluene 1 Example 1 2-Bromo-9,9-dimethyl-10-phenyl-9,10-dihydroacridine 10 mmol and N-(4-(dibenzo[b,d]furan-4-yl)phenyl )-[1,1'-biphenyl]-4-amine 15mmol,Palladium acetate 0.3 mmol, tri-tert-butylphosphine 0.3 mmol, sodium tert-butoxide25mmol, 30ml of toluene,8mmol of the target product is obtained,After the completion of the reaction, the mixture was stirred with ultrapure water, suction filtered, washed with ethanol and ultrapure water, and dried to give compound 1,
  • 5
  • [ 1319720-64-3 ]
  • [ 1372778-68-1 ]
  • [ 2375827-83-9 ]
YieldReaction ConditionsOperation in experiment
67.8% With tris-(dibenzylideneacetone)dipalladium(0); tri-tert-butyl phosphine; sodium t-butanolate In toluene at 105℃; for 24h; Inert atmosphere; 3 Example 3: Synthesis of Compound 8: In a 250 ml three-necked flask, 0.01 mol of raw material 2 was added under nitrogen protection.0.012 mol of intermediate B3, 150 ml of toluene was stirred and mixed.Then add 0.03molSodium tert-butoxide, 5 x 10-5 mol Pd2 (dba) 3, 5 x 10-5 mol tri-tert-butylphosphine,Heat to 105 ° C, reflux reaction for 24 hours, sample the plate, showing no bromine residue,The reaction is complete; it is naturally cooled to room temperature, filtered, and the filtrate is steamed under reduced pressure.(-0.09MPa, 85°C), passed through a neutral silica gel column to obtain the target product.HPLC purity 98.5%, yield 67.8%;
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