There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type
HazMat fee for 500 gram (Estimated)
Excepted Quantity
USD 0.00
Limited Quantity
USD 15-60
Inaccessible (Haz class 6.1), Domestic
USD 80+
Inaccessible (Haz class 6.1), International
USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic
USD 100+
Accessible (Haz class 3, 4, 5 or 8), International
USD 200+
Structure of 101-79-1 * Storage: {[proInfo.prStorage]}
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Stage #1: With hydrazine hydrate In ethanol at 28 - 30℃; for 0.166667 h; Stage #2: at 50 - 60℃;
General procedure: A mixture of 1-substituted-4-nitrobenzene (9.3mmol) and N2H4*H2O (27.9 mmol) in 20 ml ethanol was stirred for 10 min at 28-30 °C. The suspension of Raney-Ni in water (0.02 g, 4.41 ml) was added by stirring in three portions at 10 minute intervals. After 30 min, when reaction had subsided, stirring was continued for further 6 h at 50-60 °C. The catalyst was removed by filtration. The solvent was evaporated to obtain compounds 6-10:
Reference：
[1] Green Chemistry, 2017, vol. 19, # 14, p. 3400 - 3407
[2] Bioorganic and Medicinal Chemistry Letters, 2017, vol. 27, # 7, p. 1588 - 1592
[3] Journal of Medicinal Chemistry, 2013, vol. 56, # 11, p. 4811 - 4815
[4] Pharmazie, 1980, vol. 35, # 2, p. 78 - 80
[5] Pharmazie, 1980, vol. 35, # 2, p. 78 - 80
[6] Journal of the Chemical Society, 1927, p. 1171
[7] Journal of the Chemical Society, 1929, p. 2367
[8] Journal of the Chemical Society, 1929, p. 2367
[9] Bioorganic and Medicinal Chemistry, 2004, vol. 12, # 16, p. 4477 - 4492
[10] Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1978, vol. 16, p. 810 - 814
[11] Chemical and Pharmaceutical Bulletin, 1986, vol. 34, # 2, p. 701 - 712
[12] Journal of Medicinal Chemistry, 2002, vol. 45, # 1, p. 219 - 232
[13] Patent: US5312830, 1994, A,
[14] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 14, p. 3895 - 3898
[15] Patent: WO2013/60029, 2013, A1, . Location in patent: Paragraph 0138
[16] Patent: WO2013/63100, 2013, A1, . Location in patent: Paragraph 0138
[17] MedChemComm, 2015, vol. 6, # 4, p. 671 - 676
[18] European Journal of Medicinal Chemistry, 2016, vol. 113, p. 273 - 292
[19] Journal of Materials Chemistry A, 2018, vol. 6, # 34, p. 16680 - 16689
[20] Chemistry - A European Journal, 2018, vol. 24, # 54, p. 14418 - 14424
[21] Chem.Abstr., 1976, vol. 85, # 20843,
[22] Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 9, p. 322
2
[ 106-48-9 ]
[ 101-79-1 ]
Reference：
[1] Bioorganic and Medicinal Chemistry, 2004, vol. 12, # 16, p. 4477 - 4492
[2] Journal of Medicinal Chemistry, 2002, vol. 45, # 1, p. 219 - 232
[3] Journal of Medicinal Chemistry, 2013, vol. 56, # 11, p. 4811 - 4815
[4] MedChemComm, 2015, vol. 6, # 4, p. 671 - 676
[5] European Journal of Medicinal Chemistry, 2016, vol. 113, p. 273 - 292
[6] Bioorganic and Medicinal Chemistry Letters, 2017, vol. 27, # 7, p. 1588 - 1592
[7] Chem.Abstr., 1976, vol. 85, # 20843,
3
[ 350-46-9 ]
[ 101-79-1 ]
Reference：
[1] Bioorganic and Medicinal Chemistry, 2004, vol. 12, # 16, p. 4477 - 4492
[2] Journal of Medicinal Chemistry, 2002, vol. 45, # 1, p. 219 - 232
[3] Journal of Medicinal Chemistry, 2013, vol. 56, # 11, p. 4811 - 4815
[4] MedChemComm, 2015, vol. 6, # 4, p. 671 - 676
[5] European Journal of Medicinal Chemistry, 2016, vol. 113, p. 273 - 292
[6] Bioorganic and Medicinal Chemistry Letters, 2017, vol. 27, # 7, p. 1588 - 1592
4
[ 100-00-5 ]
[ 101-79-1 ]
Reference：
[1] Journal of the Chemical Society, 1929, p. 2367
[2] Journal of the Chemical Society, 1929, p. 2367
[3] Journal of the Chemical Society, 1927, p. 1171
[4] Chem.Abstr., 1976, vol. 85, # 20843,
Chemistry
Pharmaceutical Intermediates
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Material Science
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110K+ Compounds
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