Life Science / Inhibitors/Agonists / MAPK/ERK Pathway / p38 MAPK

Cat. No. Name/Description Purity
A1949381 Butyzamide

98%
A126618 Skatole

98%
A538658 SD-169

97%
A456071 Dihydrocaffeic acid

95%
A189058 Neflamapimod

98%
A189540 Pexmetinib

98%
A1251279 Aurantiamide

98%
A239560 Dehydrocorydaline chloride

98%
A1371131 Cornuside

98%
A341610 5,6,7-Trimethoxyflavone

97%
A1327469 Dehydromiltirone

98%
A103377 Doramapimod

99%
A277214 SB 202190

98%
A530681 PD 169316

95%
A756758 VX-702

99%
A100781 Losmapimod

98%
A725060 p38-α MAPK-IN-1

98%
A342976 Skepinone-L

98%
A468778 4-Hydroxylonchocarpin

98%
A248150 SB 203580

98%

No Data

Name/Description p38 MAPK p38α p38β Other Targets Purity
BMS-582949 +++

p38 MAPK, IC50: 13 nM

98%
SB 203580 99%+
Pexmetinib Tie-2 99%+
Skepinone-L ++++

p38α, IC50: 5 nM

99%+
Doramapimod ++++

p38α, Kd: 0.1 nM

p38α, IC50: 38 nM

99%+
SB 202190 ++

p38α, IC50: 50 nM

++

p38β, IC50: 100 nM

99%+
Losmapimod ++++

p38α, pKi: 8.1

+++

p38β, pKi: 7.6

99%+
Neflamapimod +++

p38α, IC50: 10 nM

+

p38β, IC50: 220 nM

99%+
PH-797804 ++

p38α, IC50: 26 nM

+

p38β, IC50: 102 nM

98%
TAK-715 ++++

p38α, IC50: 7.1 nM

+

p38β, IC50: 0.20 μM

99%+
VX-702 99%+
Ralimetinib dimesylate ++++

p38α, IC50: 7 nM

98+%
SB 239063 ++

p38α, IC50: 44 nM

++

p38β, IC50: 44 nM

99%+
Pamapimod +++

p38α, IC50: 0.014 μM

+

p38β, IC50: 0.48 μM

99%+
1. Hovering the mouse over the "+" can display the specific value of the relevant IC50. The more "+", the stronger the inhibitory effect. 2. "✔" Indicates that the compound has inhibitory effects on the corresponding subtypes, but there is currently no relevant data on the intensity of inhibition.