Cat. No. | Name/Description | Purity |
---|---|---|
A1949381 | Butyzamide | 98% |
A126618 | Skatole | 98% |
A538658 | SD-169 | 97% |
A456071 | Dihydrocaffeic acid | 95% |
A189058 | Neflamapimod | 98% |
A189540 | Pexmetinib | 98% |
A1251279 | Aurantiamide | 98% |
A239560 | Dehydrocorydaline chloride | 98% |
A1371131 | Cornuside | 98% |
A341610 | 5,6,7-Trimethoxyflavone | 97% |
A1327469 | Dehydromiltirone | 98% |
A103377 | Doramapimod | 99% |
A277214 | SB 202190 | 98% |
A530681 | PD 169316 | 95% |
A756758 | VX-702 | 99% |
A100781 | Losmapimod | 98% |
A725060 | p38-α MAPK-IN-1 | 98% |
A342976 | Skepinone-L | 98% |
A468778 | 4-Hydroxylonchocarpin | 98% |
A248150 | SB 203580 | 98% |
Name/Description | p38 MAPK ↓ ↑ | p38α ↓ ↑ | p38β ↓ ↑ | Other Targets | Purity | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
BMS-582949 |
+++
p38 MAPK, IC50: 13 nM |
98% | |||||||||||||||||
SB 203580 | 99%+ | ||||||||||||||||||
Pexmetinib | ✔ | Tie-2 | 99%+ | ||||||||||||||||
Skepinone-L |
++++
p38α, IC50: 5 nM |
99%+ | |||||||||||||||||
Doramapimod |
++++
p38α, Kd: 0.1 nM p38α, IC50: 38 nM |
99%+ | |||||||||||||||||
SB 202190 |
++
p38α, IC50: 50 nM |
++
p38β, IC50: 100 nM |
99%+ | ||||||||||||||||
Losmapimod |
++++
p38α, pKi: 8.1 |
+++
p38β, pKi: 7.6 |
99%+ | ||||||||||||||||
Neflamapimod |
+++
p38α, IC50: 10 nM |
+
p38β, IC50: 220 nM |
99%+ | ||||||||||||||||
PH-797804 |
++
p38α, IC50: 26 nM |
+
p38β, IC50: 102 nM |
98% | ||||||||||||||||
TAK-715 |
++++
p38α, IC50: 7.1 nM |
+
p38β, IC50: 0.20 μM |
99%+ | ||||||||||||||||
VX-702 | 99%+ | ||||||||||||||||||
Ralimetinib dimesylate |
++++
p38α, IC50: 7 nM |
98+% | |||||||||||||||||
SB 239063 |
++
p38α, IC50: 44 nM |
++
p38β, IC50: 44 nM |
99%+ | ||||||||||||||||
Pamapimod |
+++
p38α, IC50: 0.014 μM |
+
p38β, IC50: 0.48 μM |
99%+ | ||||||||||||||||
1. Hovering the mouse over the "+" can display the specific value of the relevant IC50. The more "+", the stronger the inhibitory effect. 2. "✔" Indicates that the compound has inhibitory effects on the corresponding subtypes, but there is currently no relevant data on the intensity of inhibition. |