Cat. No. | Name/Description | Purity |
---|---|---|
A206371 | GNE0877 | 99% |
A408166 | CZC-54252 | 98% |
A210153 | GNE-7915 | 98% |
A248253 | JH-II-127 | 98+% |
A125109 | PF-06447475 | 98+% |
A1601847 | EB-42486 | 98% |
A269266 | CZC-25146 | 98% |
A1177088 | PFE-360 | 98% |
A1500046 | CZC-54252 HCl | 98% |
A142087 | GSK2578215A | 98% |
A930369 | IKK 16 | 98% |
A303998 | MLi-2 | 98% |
A281167 | LRRK2-IN-1 | 98% |
A369305 | GNE-9605 | 98% |
A1680467 | GSK2646264 | 98% |
A2288218 | LRRK2-IN-6 | 98% |
A1467726 | PF-06371900 | |
A1810532 | LRRK2-IN-7 | 98% |
A1717527 | PF-06455943 | 98% |
A2250173 | (R,R)-LRRK2-IN-7 | 98% |
Name/Description | LRRK2 ↓ ↑ | Other Targets | Purity | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
GNE-7915 |
++++
LRRK2, Ki: 1 nM LRRK2, IC50: 9 nM |
99%+ | |||||||||||||||||
GNE-9605 |
+++
LRRK2, Ki: 2 nM LRRK2, IC50: 19 nM |
99%+ | |||||||||||||||||
GSK2578215A |
++
LRRK2 (G2019S), IC50: 8.9 nM LRRK2 (WT), IC50: 10.9 nM |
99%+ | |||||||||||||||||
URMC-099 |
+
LRRK2, IC50: 11 nM |
99%+ | |||||||||||||||||
PF-06447475 |
+++
LRRK2, IC50: 3nM |
99%+ | |||||||||||||||||
LRRK2-IN-1 |
++
LRRK2 (G2019S), IC50: 6 nM LRRK2 (WT), IC50: 13 nM |
99%+ | |||||||||||||||||
GNE0877 |
++++
LRRK2, Ki: 0.7 nM |
99%+ | |||||||||||||||||
1. Hovering the mouse over the "+" can display the specific value of the relevant IC50. The more "+", the stronger the inhibitory effect. 2. "✔" Indicates that the compound has inhibitory effects on the corresponding subtypes, but there is currently no relevant data on the intensity of inhibition. |