Chemistry Organic Building Blocks Hydrazides
Hydrazides, in the realm of organic chemistry, are a category of organic compounds denoted by the formula RNHNH2, where R represents acyl (R'CO-), sulfonyl (R'SO2-), or phosphoryl (R'2P(O)-) groups.
Hydrazide analogues exhibit diverse biological activities, including but not limited to antidepressant, anticonvulsant, anti-inflammatory, antibacterial, antimalarial, anticancer, and antimicrobial properties.
Hydrazides are typically synthesized through the reaction of acid derivatives, such as esters, acid chlorides, or amides, with hydrazine.
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N'-((2S,3S)-2-(Benzyloxy)pentan-3-yl)formohydrazide oxalate
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7-Diethylaminocoumarin-3-carbohydrazide
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1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine
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N-(6-Methyl-3-oxo-2,3-dihydro-1,2,4-triazin-4(5H)-yl)acetamide