Life Science / Inhibitors/Agonists / Epigenetics / Histone Methyltransferase

Cat. No. Name/Description Purity
A221541 AMI-1 free acid

98%
A117299 Sorafenib Tosylate

98%
A662558 Valemetostat

99%
A1364995 VTP50469

98%
A1867696 BMF-219

98%
A550753 AZ505

99%
A1547311 MRTX9768

95%
A713137 Sinefungin

98%
A746301 3-Deazaneplanocin A HCl

98%
A345312 EZM 2302

97%
A852233 A-395

98%
A1216638 Valemetostat tosylate

98%
A933282 A-196

98%
A1176455 Onametostat

99%
A1327306 MS1943

98%
A211708 UNC0379

98%
A354382 UNC0321

98%
A567534 MS049

98%
A391113 AZ505 ditrifluoroacetate

98%
A464128 UNC0642

98%

No Data

Name/Description Histone Methyltransferase Other Targets Purity
BRD4770 99%+
UNC1999 +++

EZH2, IC50: 2 nM

EZH1, IC50: 45 nM

99%+
EPZ005687 ++

EZH2, Ki: 24 nM

99%+
EPZ015666 +++

PRMT5, Ki: 5 nM

99%+
3-Deazaneplanocin A HCl ++++

S-adenosylhomocysteine hydrolase, Ki: 50 pM

99%+
EPZ6438 +++

EZH2, IC50: 11 nM

EZH2, Ki: 2.5 nM

98%
GSK126 ++

EZH2, IC50: 9.9 nM

99%+
MI-3 +

Menin-MLL, IC50: 648 nM

98+%
MM-102 ++

MLL1, IC50: 0.4 μM

99%
EI1 ++

EZH2 (Y641F), IC50: 13 nM

Ezh2 (wild-type), IC50: 15 nM

99%+
SGC0946 ++++

DOT1L, IC50: 0.3 nM

99%+
PFI-2 HCl ++++

SETD7, Ki: 0.33 nM

SETD7, IC50: 2 nM

99%+
Pinometostat ++++

DOT1L, Ki: 80 pM

99%+
EPZ004777 +++

DOT1L, IC50: 0.4 nM

99%+
Entacapone ++

COMT, IC50: 151 nM

95%
UNC0379 +

SETD8, IC50: 7.9 μM

99%+
Menin-MLL inhibitor MI-2 +

Menin-MLL, IC50: 446 nM

98+%
GSK343 +++

EZH2, IC50: 4 nM

EZH1, IC50: 240 nM

99%+
BIX-01294 3HCl +

G9a, IC50: 2.7 μM

99%+
1. Hovering the mouse over the "+" can display the specific value of the relevant IC50. The more "+", the stronger the inhibitory effect. 2. "✔" Indicates that the compound has inhibitory effects on the corresponding subtypes, but there is currently no relevant data on the intensity of inhibition.