Cat. No. | Name/Description | Purity |
---|---|---|
A134996 | Masitinib | 98% |
A1535395 | Narmafotinib | 95% |
A640498 | Batatasin III | 97% |
A103079 | PND-1186 | 98% |
A325541 | PF-431396 | 95+% |
A318281 | GSK2256098 | 98% |
A230913 | PF-573228 | 98% |
A740806 | Defactinib HCl | 98+% |
A1598840 | FAK-IN-7 | 95% |
A554072 | PF-562271 besylate | 98% |
A742025 | SU6656 | 98% |
A121000 | NVP-TAE 226 | 98+% |
A191099 | Y15 | 97% |
A173517 | CTX-0294885 | 98% |
A1598863 | FAK-IN-10 | 95% |
A143423 | Defactinib | 99% |
A1601210 | YH-306 | 98% |
A301515 | PF-562271 | 98+% |
A1441509 | PND-1186 HCl | 98% |
A1682326 | FLT3-IN-17 | 98% |
Name/Description | FAK ↓ ↑ | Other Targets | Purity | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Defactinib | ✔ | 99%+ | |||||||||||||||||
NVP-TAE 226 |
++
FAK, IC50: 5.5 nM PYK2, IC50: 3.5 nM |
IGF-1R,Insulin Receptor | 99%+ | ||||||||||||||||
PF-573228 |
+
FAK, IC50: 4 nM |
99%+ | |||||||||||||||||
PF-431396 |
++
FAK, IC50: 2 nM PYK2, IC50: 11 nM |
99%+ | |||||||||||||||||
PND-1186 |
++++
FAK, IC50: 1.5 nM |
99%+ | |||||||||||||||||
PF-562271 |
++++
FAK, IC50: 1.5 nM PYK2, IC50: 13 nM |
99%+ | |||||||||||||||||
GSK2256098 |
++++
FAK, Ki: 0.4 nM |
99%+ | |||||||||||||||||
1. Hovering the mouse over the "+" can display the specific value of the relevant IC50. The more "+", the stronger the inhibitory effect. 2. "✔" Indicates that the compound has inhibitory effects on the corresponding subtypes, but there is currently no relevant data on the intensity of inhibition. |